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Full-Text Articles in Medicine and Health Sciences

Assessing Risk In Focal Arboviral Infections: Are We Missing The Big Or Little Picture?, A D. Haddow, Agricola Odoi, C J. Jones Sep 2009

Assessing Risk In Focal Arboviral Infections: Are We Missing The Big Or Little Picture?, A D. Haddow, Agricola Odoi, C J. Jones

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

BACKGROUND: Focal arboviral infections affecting a subset of the overall population present an often overlooked set of challenges in the assessment and reporting of risk and the detection of spatial patterns. Our objective was to assess the variation in risk when using different at-risk populations and geographic scales for the calculation of incidence risk and the detection of geographic hot-spots of infection. We explored these variations using a pediatric arbovirus, La Crosse virus (LACV), as our model. METHODS AND FINDINGS: Descriptive and cluster analyses were performed on probable and confirmed cases of LACV infections reported to the Tennessee Department of …


Development Of A Mechanistic Model To Represent The Dynamics Of Particle Flow Out Of The Rumen And To Predict Rate Of Passage Of Forage Particles In Dairy Cattle., S Seo, Cristina Lanzas, L O. Tedeschi, A Pell, D G. Fox Aug 2009

Development Of A Mechanistic Model To Represent The Dynamics Of Particle Flow Out Of The Rumen And To Predict Rate Of Passage Of Forage Particles In Dairy Cattle., S Seo, Cristina Lanzas, L O. Tedeschi, A Pell, D G. Fox

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

A mechanistic and dynamic model was developed to represent physiological aspects of particle dynamics in the reticulo-rumen (RR) and to predict rate of passage out of the RR (Kp) of forage particles quantitatively. The model consists of 2 conceptual pools with 3 spatial compartments of particles; the compartment the particle enters is based on functional specific gravity (FSG). The model assumes 2 major pressure gradient-driven flows of particles out of the RR through the reticulo-omasal orifice between 2 consecutive primary reticular contractions. One is associated with the second phase of primary reticular contraction and involves propulsion of particles in the …


Modeling On-Farm Escherichia Coli O157:H7 Population Dynamics, P Ayscue, Cristina Lanzas, R Ivanek, Y T. Grohn May 2009

Modeling On-Farm Escherichia Coli O157:H7 Population Dynamics, P Ayscue, Cristina Lanzas, R Ivanek, Y T. Grohn

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Escherichia coli O157:H7 is a potentially fatal foodborne pathogen with a putative reservoir for human infection in feedlot cattle. In order to more effectively identify targets for intervention strategies, we aimed to (1) assess the role of various feedlot habitats in E. coli O157:H7 propagation and (2) provide a framework for examining the relative contributions of animals and the surrounding environment to observed pathogen dynamics. To meet these goals we developed a mathematical model based on an ecological metapopulation framework to track bacterial population dynamics inside and outside the host. We used E. coli O157:H7 microbiological and epidemiological literature to …


Comparison Of A Human Portable Blood Glucose Monitor, A Veterinary Portable Blood Glucose Monitor And An Automated Chemistry Analyzer For Measuring Canine Blood Glucose Concentration, B M. Johnson, Michael M. Fry, B Flatland, C A. Kirk Jan 2009

Comparison Of A Human Portable Blood Glucose Monitor, A Veterinary Portable Blood Glucose Monitor And An Automated Chemistry Analyzer For Measuring Canine Blood Glucose Concentration, B M. Johnson, Michael M. Fry, B Flatland, C A. Kirk

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

OBJECTIVE: To compare blood glucose concentrations measured with 2 portable blood glucose meters (PBGMs) validated for use in dogs (PBGM-D) and humans (PBGM-H) and an automated chemistry analyzer. DESIGN: Validation study. SAMPLE POPULATION: 92 samples of fresh whole blood and plasma from 83 dogs with various diseases. PROCEDURES: Each PBGM was used to measure whole blood glucose concentration, and the automated analyzer was used to measure plasma glucose concentration. Passing-Bablok linear regression and Bland-Altman plots were used to determine correlations and bias between the PBGMs and the automated analyzer. Calculated acceptability limits based on combined inherent instrument imprecision were used …