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Full-Text Articles in Medicine and Health Sciences
The Effect Of Heterogeneous Infectious Period And Contagiousness On The Dynamics Of Salmonella Transmission In Dairy Cattle, Cristina Lanzas, S Brien, R Ivanek, Y Lo, P P. Chapagain, K A. Ray, P Ayscue, L D. Warnick, Y T. Grohn
The Effect Of Heterogeneous Infectious Period And Contagiousness On The Dynamics Of Salmonella Transmission In Dairy Cattle, Cristina Lanzas, S Brien, R Ivanek, Y Lo, P P. Chapagain, K A. Ray, P Ayscue, L D. Warnick, Y T. Grohn
Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences
The objective of this study was to address the impact of heterogeneity of infectious period and contagiousness on Salmonella transmission dynamics in dairy cattle populations. We developed three deterministic SIR-type models with two basic infected stages (clinically and subclinically infected). In addition, model 2 included long-term shedders, which were defined as individuals with low contagiousness but long infectious period, and model 3 included super-shedders (individuals with high contagiousness and long infectious period). The simulated dynamics, basic reproduction number (R0) and critical vaccination threshold were studied. Clinically infected individuals were the main force of infection transmission for models 1 and 2. …
The Risk And Control Of Salmonella Outbreaks In Calf-Raising Operations: A Mathematical Modeling Approach, Cristina Lanzas, L D. Warnick, R Ivanek, P Ayscue, D V. Nydam, Y T. Grohn
The Risk And Control Of Salmonella Outbreaks In Calf-Raising Operations: A Mathematical Modeling Approach, Cristina Lanzas, L D. Warnick, R Ivanek, P Ayscue, D V. Nydam, Y T. Grohn
Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences
Salmonellosis in calves has economic and welfare implications, and serves as a potential source of human infections. Our objectives were to assess the risk of Salmonella spread following its introduction into a herd of pre-weaned calves and to evaluate the efficacy of control strategies to prevent and control outbreaks. To meet these objectives, we developed a model of Salmonella transmission within a pre-weaned group of calves based on a well documented outbreak of salmonellosis in a calf-raising operation and other literature. Intervention scenarios were evaluated in both deterministic and stochastic versions of the model. While the basic reproduction number (R0) …
The Effect Of Heterogeneous Infectious Period And Contagiousness On The Dynamics Of Salmonella Transmission In Dairy Cattle, Cristina Lanzas, S Brien, R Ivanek, Y Lo, P P. Chapagain, K A. Ray, P Ayscue, L D. Warnick, Y T. Grohn
The Effect Of Heterogeneous Infectious Period And Contagiousness On The Dynamics Of Salmonella Transmission In Dairy Cattle, Cristina Lanzas, S Brien, R Ivanek, Y Lo, P P. Chapagain, K A. Ray, P Ayscue, L D. Warnick, Y T. Grohn
Cristina Lanzas
The objective of this study was to address the impact of heterogeneity of infectious period and contagiousness on Salmonella transmission dynamics in dairy cattle populations. We developed three deterministic SIR-type models with two basic infected stages (clinically and subclinically infected). In addition, model 2 included long-term shedders, which were defined as individuals with low contagiousness but long infectious period, and model 3 included super-shedders (individuals with high contagiousness and long infectious period). The simulated dynamics, basic reproduction number (R0) and critical vaccination threshold were studied. Clinically infected individuals were the main force of infection transmission for models 1 and 2. …
The Risk And Control Of Salmonella Outbreaks In Calf-Raising Operations: A Mathematical Modeling Approach, Cristina Lanzas, L D. Warnick, R Ivanek, P Ayscue, D V. Nydam, Y T. Grohn
The Risk And Control Of Salmonella Outbreaks In Calf-Raising Operations: A Mathematical Modeling Approach, Cristina Lanzas, L D. Warnick, R Ivanek, P Ayscue, D V. Nydam, Y T. Grohn
Cristina Lanzas
Salmonellosis in calves has economic and welfare implications, and serves as a potential source of human infections. Our objectives were to assess the risk of Salmonella spread following its introduction into a herd of pre-weaned calves and to evaluate the efficacy of control strategies to prevent and control outbreaks. To meet these objectives, we developed a model of Salmonella transmission within a pre-weaned group of calves based on a well documented outbreak of salmonellosis in a calf-raising operation and other literature. Intervention scenarios were evaluated in both deterministic and stochastic versions of the model. While the basic reproduction number (R0) …
Amyloid Fibrils: Potential Food Safety Implications, Michael Greger
Amyloid Fibrils: Potential Food Safety Implications, Michael Greger
Human Health Collection
The demonstration of oral Amyloid-A (AA) fibril transmissibility has raised food safety questions about the consumption of amyloidotic viscera. In a presumed prion-like mechanism, amyloid fibrils have been shown to trigger and accelerate the development of AA amyloidosis in rodent models. The finding of amyloid fibrils in edible avian and mammalian food animal tissues, combined with the inability of cooking temperatures to eliminate their amyloidogenic potential, has led to concerns that products such as pâté de foie gras may activate a reactive systemic amyloidosis in susceptible consumers. Given the ability of amyloid fibrils to cross-seed the formation of chemically heterologous …