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Articles 1 - 30 of 243
Full-Text Articles in Medicine and Health Sciences
Host Range, Biology, And Species Specificity Of Seven-Segmented Influenza Viruses—A Comparative Review On Influenza C And D, Chithra Sreenivasan, Zizhang Sheng, Dan Wang, Feng Li
Host Range, Biology, And Species Specificity Of Seven-Segmented Influenza Viruses—A Comparative Review On Influenza C And D, Chithra Sreenivasan, Zizhang Sheng, Dan Wang, Feng Li
Maxwell H. Gluck Equine Research Center Faculty Publications
Other than genome structure, influenza C (ICV), and D (IDV) viruses with seven-segmented genomes are biologically different from the eight-segmented influenza A (IAV), and B (IBV) viruses concerning the presence of hemagglutinin–esterase fusion protein, which combines the function of hemagglutinin and neuraminidase responsible for receptor-binding, fusion, and receptor-destroying enzymatic activities, respectively. Whereas ICV with humans as primary hosts emerged nearly 74 years ago, IDV, a distant relative of ICV, was isolated in 2011, with bovines as the primary host. Despite its initial emergence in swine, IDV has turned out to be a transboundary bovine pathogen and a broader host range, …
Cyathostomin Resistance To Moxidectin And Combinations Of Anthelmintics In Australian Horses, Ghazanfar Abbas, Abdul Ghafar, John Hurley, Jenni Bauquier, Anne Beasley, Edwina J. A. Wilkes, Caroline Jacobson, Charles El-Hage, Lucy Cudmore, Peter Carrigan, Brett Tennent-Brown, Charles G. Gauci, Martin K. Nielsen, Kristopher J. Hughes, Ian Beveridge, Abdul Jabbar
Cyathostomin Resistance To Moxidectin And Combinations Of Anthelmintics In Australian Horses, Ghazanfar Abbas, Abdul Ghafar, John Hurley, Jenni Bauquier, Anne Beasley, Edwina J. A. Wilkes, Caroline Jacobson, Charles El-Hage, Lucy Cudmore, Peter Carrigan, Brett Tennent-Brown, Charles G. Gauci, Martin K. Nielsen, Kristopher J. Hughes, Ian Beveridge, Abdul Jabbar
Veterinary Science Faculty Publications
BACKGROUND: Cyathostomins are the most important and common parasitic nematodes of horses, with > 50 species known to occur worldwide. The frequent and indiscriminate use of anthelmintics has resulted in the development of anthelmintic resistance (AR) in horse nematodes. In this study we assessed the efficacy of commonly used anthelmintics against cyathostomins in Australian thoroughbred horses.
METHODS: Two drug efficacy trials per farm were conducted on two thoroughbred horse farms in the state of Victoria, Australia. In the first trial, the horses on Farm A were treated with single and combinations of anthelmintics, including oxfendazole (OFZ), abamectin (ABM), abamectin and morantel …
Landscape Transformations Produce Favorable Roosting Conditions For Turkey Vultures And Black Vultures, Jacob E. Hill, Kenneth F. Kellner, Bryan M. Kluever, Michael L. Avery, John S. Humphrey, Eric A. Tillman, Travis L. Devault, Jerrold L. Belant
Landscape Transformations Produce Favorable Roosting Conditions For Turkey Vultures And Black Vultures, Jacob E. Hill, Kenneth F. Kellner, Bryan M. Kluever, Michael L. Avery, John S. Humphrey, Eric A. Tillman, Travis L. Devault, Jerrold L. Belant
USDA Wildlife Services: Staff Publications
Recent increases in turkey vulture (Cathartes aura) and black vulture (Coragyps atratus) populations in North America have been attributed in part to their success adapting to human-modified landscapes. However, the capacity for such landscapes to generate favorable roosting conditions for these species has not been thoroughly investigated. We assessed the role of anthropogenic and natural landscape elements on roosting habitat selection of 11 black and 7 turkey vultures in coastal South Carolina, USA using a GPS satellite transmitter dataset derived from previous research. Our dataset spanned 2006–2012 and contained data from 7916 nights of roosting. Landscape …
Towards A More Comprehensive Understanding Of Wild Pig (Sus Scrofa) Impacts On Agricultural Producers: Insights From A Texas Case Study, Keith M. Carlisle, Nicole Didero, Sophie Mckee, Julie Elser, Stephanie A. Shwiff
Towards A More Comprehensive Understanding Of Wild Pig (Sus Scrofa) Impacts On Agricultural Producers: Insights From A Texas Case Study, Keith M. Carlisle, Nicole Didero, Sophie Mckee, Julie Elser, Stephanie A. Shwiff
USDA Wildlife Services: Staff Publications
This research investigates the impacts of invasive wild pigs (Sus scrofa Linneaus) on agricultural producers in Texas, with the aim of identifying and describing all categories of wild pig impacts and quantifying the extent of producers’ over- or underestimation of their total wild pig-related costs in 2018, as compared to calculations based upon data subsequently provided by the producers about individual wild pig-related costs and losses. Based on interviews with 23 producers in 16 Texas counties, we identified more than 20 discrete categories of negative impacts and negligible positive impacts associated with wild pigs. Among them were categories that have …
Sex And Nest Type Influence Avian Blood Parasite Prevalence In A High-Elevation Bird Community, Marina D. Rodriguez, Paul F. Doherty, Antoinette J. Piaggio, Kathryn P. Huyvaert
Sex And Nest Type Influence Avian Blood Parasite Prevalence In A High-Elevation Bird Community, Marina D. Rodriguez, Paul F. Doherty, Antoinette J. Piaggio, Kathryn P. Huyvaert
USDA Wildlife Services: Staff Publications
Background: The prevalence of avian haemosporidian parasites and the factors influencing infection in the Colorado Rocky Mountains are largely unknown. With climate change expected to promote the expansion of vector and avian blood parasite distributions, baseline knowledge and continued monitoring of the prevalence and diversity of these parasites is needed.
Methods: Using an occupancy modeling framework, we conducted a survey of haemosporidian parasite species infecting an avian community in the Colorado Rocky Mountains in order to estimate the prevalence and diversity of blood parasites and to investigate species-level and individual-level characteristics that may influence infection.
Results: We estimated the prevalence …
Reproductive Success Of Captive-Reared Allegheny Woodrats (Neotoma Magister) Released Into Genetically Depauperate Populations, Miracle M. Davis, Timothy J. Smyser, Scott A. Johnson, Joseph Duchamp, Jeffery L. Larkin, Robert K. Swihart, Jacqueline M. Doyle
Reproductive Success Of Captive-Reared Allegheny Woodrats (Neotoma Magister) Released Into Genetically Depauperate Populations, Miracle M. Davis, Timothy J. Smyser, Scott A. Johnson, Joseph Duchamp, Jeffery L. Larkin, Robert K. Swihart, Jacqueline M. Doyle
USDA Wildlife Services: Staff Publications
Habitat fragmentation and degradation have led to a proliferation of small and isolated populations that are vulnerable to genetic erosion. Reduction in habitat and concomitant declines in population connectivity can expediate the collapse of species that exist as natural metapopulations. In recent years, Allegheny woodrats (Neotoma magister) have experienced local extirpations and declines in genetic diversity across their range due to disease-related mortality, reduced food availability, and disruption of connectivity among subpopulations. In response, we developed a captive-breeding program to facilitate genetic management of isolated woodrat populations in Indiana. Between 2010 and 2012, 27 captive-reared individuals were released to four …
Economic Estimates Of Wild Hog (Sus Scrofa) Damage And Control Among Young Forest Plantations In Alabama, Micah Fern, Rebecca Barlow, Chris Slootmaker, John Kush, Stephanie Shwiff, Larry Teeter, Jim Armstrong
Economic Estimates Of Wild Hog (Sus Scrofa) Damage And Control Among Young Forest Plantations In Alabama, Micah Fern, Rebecca Barlow, Chris Slootmaker, John Kush, Stephanie Shwiff, Larry Teeter, Jim Armstrong
USDA Wildlife Services: Staff Publications
Operating as ecological engineers, the increased distribution and abundance of wild hogs (Sus scrofa) has caused considerable socio-economic impacts. The international scope of economic research providing wild hog damage estimates are often confined to agricultural crops, while damage estimates among forest plantations are lacking. In Alabama, private landowners hold the majority of timberland acreage and are less equipped to absorb financial losses from wild hog damage than their industrial counterparts. A survey was conducted to estimate the economic impact of wild hogs, namely costs of damage and control, to privately owned forestlands. The survey was distributed in the …
Responses Of Turkey Vultures To Unmanned Aircraft Systems Vary By Platform, Morgan B. Pfeiffer, Bradley F. Blackwell, Thomas W. Seamans, Bruce N. Buckingham, Joshua L. Hoblet, Patrice E. Baumhardt
Responses Of Turkey Vultures To Unmanned Aircraft Systems Vary By Platform, Morgan B. Pfeiffer, Bradley F. Blackwell, Thomas W. Seamans, Bruce N. Buckingham, Joshua L. Hoblet, Patrice E. Baumhardt
USDA Wildlife Services: Staff Publications
A challenge that conservation practitioners face is manipulating behavior of nuisance species. The turkey vulture (Cathartes aura) can cause substantial damage to aircraft if struck. The goal of this study was to assess vulture responses to unmanned aircraft systems (UAS) for use as a possible dispersal tool. Our treatments included three platforms (fixed-wing, multirotor, and a predator-like ornithopter [powered by flapping flight]) and two approach types (30 m overhead or targeted towards a vulture) in an operational context. We evaluated perceived risk as probability of reaction, reaction time, flight-initiation distance (FID), vulture remaining index, and latency to return. …
Potential Use For Serosurveillance Of Feral Swine To Map Risk For Anthrax Exposure, Texas, Usa, Rachel M. Maison, Courtney F. Pierce, Izabela K. Ragan, Vienna R. Brown, Michael J. Bodenchuk, Richard A. Bowen, Angela M. Bosco-Lauth
Potential Use For Serosurveillance Of Feral Swine To Map Risk For Anthrax Exposure, Texas, Usa, Rachel M. Maison, Courtney F. Pierce, Izabela K. Ragan, Vienna R. Brown, Michael J. Bodenchuk, Richard A. Bowen, Angela M. Bosco-Lauth
USDA Wildlife Services: Staff Publications
Anthrax is a disease of concern in many mammals, including humans. Management primarily consists of prevention through vaccination and tracking clinical-level observations because environmental isolation is laborious and bacterial distribution across large geographic areas diffi cult to confi rm. Feral swine (Sus scrofa) are an invasive species with an extensive range in the southern United States that rarely succumbs to anthrax. We present evidence that feral swine might serve as biosentinels based on comparative seroprevalence in swine from historically defi ned anthrax-endemic and non–anthraxendemic regions of Texas. Overall seropositivity was 43.7% (n = 478), and logistic regression revealed county endemicity …
Deterring Non-Target Birds From Toxic Bait Sites For Wild Pigs, Nathan P. Snow, Joseph M. Halseth, Justin A. Foster, Michael J. Lavelle, Justin W. Fischer, Michael P. Glow, Ingrid A. Messer, Seth M. Cook, Kurt C. Vercauteren
Deterring Non-Target Birds From Toxic Bait Sites For Wild Pigs, Nathan P. Snow, Joseph M. Halseth, Justin A. Foster, Michael J. Lavelle, Justin W. Fischer, Michael P. Glow, Ingrid A. Messer, Seth M. Cook, Kurt C. Vercauteren
USDA Wildlife Services: Staff Publications
Toxic baiting of wild pigs (Sus scrofa) is a potential new tool for population control and damage reduction in the US. Field trials testing a prototype toxic bait (HOGGONE 2 containing 5% sodium nitrite [SN]), though, revealed that wild pigs spilled small particles of toxic bait outside of bait stations which subsequently created hazards for non-target species that consumed those particles, primarily passerine birds. To deter non-target birds from consuming particles of spilled bait, we tested four deterrents at mock bait sites (i.e., baited with bird seed) in north-central Colorado, USA during April–May 2020. We found a programable, inflatable deterrent …
How Do Genetic Relatedness And Spatial Proximity Shape African Swine Fever Infections In Wild Boar?, Tomasz Podgórski, Kim M. Pepin, Anna Radko, Angelika Podbielska, Magdalena Łyjak, Grzegorz Woźniakowski, Tomasz Borowik
How Do Genetic Relatedness And Spatial Proximity Shape African Swine Fever Infections In Wild Boar?, Tomasz Podgórski, Kim M. Pepin, Anna Radko, Angelika Podbielska, Magdalena Łyjak, Grzegorz Woźniakowski, Tomasz Borowik
USDA Wildlife Services: Staff Publications
The importance of social and spatial structuring of wildlife populations for disease spread, though widely recognized, is still poorly understood in many host-pathogen systems. In particular, system-specific kin relationships among hosts can create contact heterogeneities and differential disease transmission rates. Here, we investigate how distance-dependent infection risk is influenced by genetic relatedness in a novel host-pathogen system: wild boar (Sus scrofa) and African swine fever (ASF).We hypothesized that infection risk would correlate positively with proximity and relatedness to ASF-infected individuals but expected those relationships to weaken with the distance between individuals due to decay in contact rates and …
Guidance For Management Of Free-Roaming Community Cats: A Bioeconomic Analysis, Valeria A. Benka, John D. Boone, Philip S. Miller, Joyce R. Briggs, Aaron M. Anderson, Christopher Slootmaker, Margaret Slater, Julie K. Levy, Felicia B. Nutter, Stephen Zawistowski
Guidance For Management Of Free-Roaming Community Cats: A Bioeconomic Analysis, Valeria A. Benka, John D. Boone, Philip S. Miller, Joyce R. Briggs, Aaron M. Anderson, Christopher Slootmaker, Margaret Slater, Julie K. Levy, Felicia B. Nutter, Stephen Zawistowski
Publications and Research
Objectives This study used computer simulation modeling to estimate and compare costs of different free-roaming cat (FRC) management options (lethal and non-lethal removal, trap–neuter–return, combinations of these options and no action) and their ability to reduce FRC population abundance in open demographic settings. The findings provide a resource for selecting management approaches that are well matched for specific communities, goals and timelines, and they represent use of best available science to address FRC issues.
Methods Multiple FRC management approaches were simulated at varying intensities using a stochastic individual- based model in the software package Vortex. Itemized costs were obtained from …
Chemical And Biological Characterization Of The Anticancer Potency Of Salvia Fruticosa In A Model Of Human Malignant Melanoma, Sotiris Kyriakou, Venetia Tragkola, Michael Plioukas, Ioannis Anestopoulos, Paschalina S. Chatzopoulou, Eirini Sarrou, Dimitrios T. Trafalis, Maria V. Deligiorgi, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidi
Chemical And Biological Characterization Of The Anticancer Potency Of Salvia Fruticosa In A Model Of Human Malignant Melanoma, Sotiris Kyriakou, Venetia Tragkola, Michael Plioukas, Ioannis Anestopoulos, Paschalina S. Chatzopoulou, Eirini Sarrou, Dimitrios T. Trafalis, Maria V. Deligiorgi, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidi
School of Veterinary and Biomedical Sciences: Faculty Publications
Malignant melanoma is one of the most aggressive types of skin cancer with an increasing incidence worldwide. Thus, the development of innovative therapeutic approaches is of great importance. Salvia fruticosa (SF) is known for its anticancer properties and in this context, we aimed to investigate its potential anti-melanoma activity in an in vitro model of human malignant melanoma. Cytotoxicity was assessed through a colorimetric-based sulforhodamine-B (SRB) assay in primary malignant melanoma (A375), non-malignant melanoma epidermoid carcinoma (A431) and non-tumorigenic melanocyte neighbouring keratinocyte (HaCaT) cells. Among eight (8) different fractions of S. fruticosa extracts (SF1-SF8) tested, SF3 was found to possess …
Mt10-Cvb3 Vaccine Virus Protects Against Cvb4 Infection By Inducing Cross-Reactive, Antigen-Specific Immune Responses, Ninaad Lasrado, Rajkumar Arumugam, Mahima T. Rasquinha, Meghna Sur, David Steffen, Jay Reddy
Mt10-Cvb3 Vaccine Virus Protects Against Cvb4 Infection By Inducing Cross-Reactive, Antigen-Specific Immune Responses, Ninaad Lasrado, Rajkumar Arumugam, Mahima T. Rasquinha, Meghna Sur, David Steffen, Jay Reddy
School of Veterinary and Biomedical Sciences: Faculty Publications
Group B coxsackieviruses (CVB) containing six serotypes, B1–B6, affect various organs, and multiple serotypes can induce similar diseases such as myocarditis and pancreatitis. Yet, no vaccines are currently available to prevent these infections. Translationally, the derivation of vaccines that offer protection against multiple serotypes is highly desired. In that direction, we recently reported the generation of an attenuated strain of CVB3, termed Mt10, which completely protects against both myocarditis and pancreatitis induced by the homologous wild-type CVB3 strain. Here, we report that the Mt10 vaccine can induce cross-protection against multiple CVB serotypes as demonstrated with CVB4. We note that the …
Estrogens Regulate Placental Angiogenesis In Horses, Shingo Haneda, Pouya Dini, Alejandro Esteller-Vico, Kirsten E. Scoggin, Edward L. Squires, Mats H. T. Troedsson, Peter Daels, Yasuo Nambo, Barry A. Ball
Estrogens Regulate Placental Angiogenesis In Horses, Shingo Haneda, Pouya Dini, Alejandro Esteller-Vico, Kirsten E. Scoggin, Edward L. Squires, Mats H. T. Troedsson, Peter Daels, Yasuo Nambo, Barry A. Ball
Maxwell H. Gluck Equine Research Center Faculty Publications
A sufficient vascular network within the feto-maternal interface is necessary for placental function. Several pregnancy abnormalities have been associated with abnormal vascular formations in the placenta. We hypothesized that growth and expansion of the placental vascular network in the equine (Equus caballus) placenta is regulated by estrogens (estrogen family hormones), a hormone with a high circulating concentration during equine gestation. Administration of letrozole, a potent and specific inhibitor of aromatase, during the first trimester (D30 to D118), decreased circulatory estrone sulfate concentrations, increased circulatory testosterone and androstenedione concentrations, and tended to reduce the weight of the fetus ( …
Wildlife Responses To Livestock Guard Dogs And Domestic Sheep On Open Range, Daniel Kinka, Jeffrey T. Schultz, Julie K. Young
Wildlife Responses To Livestock Guard Dogs And Domestic Sheep On Open Range, Daniel Kinka, Jeffrey T. Schultz, Julie K. Young
USDA Wildlife Services: Staff Publications
Domestic sheep (Ovis aries) are an attractant to carnivores; however, sheep are often accompanied by humans and livestock guardian dogs (LGDs; Canis familiaris), which defend sheep from depredation. Sheep also compete directly with wildlife for grazing resources. Although practiced for millennia in much of the world outside North America, the effect that transhumance has on wildlife is poorly understood. To test the effect of sheep bands (sheep, humans, and LGDs) on wildlife, we modeled the detection probability of wild mammals relative to the presence of sheep bands in the Northwestern United States. Sheep band presence was associated …
Mongooses (Urva Auropunctata) As Reservoir Hosts Of Leptospira Species In The United States Virgin Islands, 2019–2020, Hannah M. Cranford, A. Springer Browne, Karen Lecount, Tammy Anderson, Camila Hamond, Linda Schlater, Tod Stuber, Valicia J. Burke-France, Marissa Taylor, Cosme J. Harrison, Katia Y. Matias, Alexandra Medley, John Rossow, Nicholas Wiese, Leanne Jankelunas, Leah De Wilde, Michelle Mehalick, Gerard L. Blanchard, Keith R. Garcia, Alan S. Mckinley, Claudia D. Lombard, Nicole F. Angeli, David Horner, Thomas Kelley, David J. Worthington, Jennifer Valiulis, Bethany Bradford, Are Berentsen, Johanna S. Salzer, Renee Galloway, Ilana J. Schafer, Kristine Bisgard, Joseph Roth, Brett R. Ellis, Esther M. Ellis, Jarlath E. Nally
Mongooses (Urva Auropunctata) As Reservoir Hosts Of Leptospira Species In The United States Virgin Islands, 2019–2020, Hannah M. Cranford, A. Springer Browne, Karen Lecount, Tammy Anderson, Camila Hamond, Linda Schlater, Tod Stuber, Valicia J. Burke-France, Marissa Taylor, Cosme J. Harrison, Katia Y. Matias, Alexandra Medley, John Rossow, Nicholas Wiese, Leanne Jankelunas, Leah De Wilde, Michelle Mehalick, Gerard L. Blanchard, Keith R. Garcia, Alan S. Mckinley, Claudia D. Lombard, Nicole F. Angeli, David Horner, Thomas Kelley, David J. Worthington, Jennifer Valiulis, Bethany Bradford, Are Berentsen, Johanna S. Salzer, Renee Galloway, Ilana J. Schafer, Kristine Bisgard, Joseph Roth, Brett R. Ellis, Esther M. Ellis, Jarlath E. Nally
USDA Wildlife Services: Staff Publications
During 2019–2020, the Virgin Islands Department of Health investigated potential animal reservoirs of Leptospira spp., the bacteria that cause leptospirosis. In this cross-sectional study, we investigated Leptospira spp. exposure and carriage in the small Indian mongoose (Urva auropunctata, syn: Herpestes auropunctatus), an invasive animal species. This study was conducted across the three main islands of the U.S. Virgin Islands (USVI), which are St. Croix, St. Thomas, and St. John. We used the microscopic agglutination test (MAT), fluorescent antibody test (FAT), real-time polymerase chain reaction (lipl32 rt-PCR), and bacterial culture to evaluate serum and kidney specimens and compared the …
Rooting Out Genetic Structure Of Invasive Wild Pigs In Texas, Anna M. Mangan, Antoinette J. Piaggio, Michael J. Bodenchuk, Courtney F. Pierce, Timothy J. Smyser
Rooting Out Genetic Structure Of Invasive Wild Pigs In Texas, Anna M. Mangan, Antoinette J. Piaggio, Michael J. Bodenchuk, Courtney F. Pierce, Timothy J. Smyser
USDA Wildlife Services: Staff Publications
Invasive wild pigs (Sus scrofa), also called feral swine or wild hogs, are recognized as among the most destructive invasive species in the world. Throughout the United States, invasive wild pigs have expanded rapidly over the past 40 years with populations now established in 38 states. Of the estimated 6.9 million wild pigs distributed throughout the United States, Texas supports approximately 40% of the population and similarly bears disproportionate ecological and economic costs. Genetic analyses are an effective tool for understanding invasion pathways and tracking dispersal of invasive species such as wild pigs and have been used recently …
Decoding The Equine Genome: Lessons From Encode, Sichong Peng, Jessica L. Petersen, Rebecca R. Bellone, Theodore S. Kalbfleisch, N. B. Kingsley, Alexa M. Barber, Eleonora Cappelletti, Elena Giulotto, Carrie J. Finno
Decoding The Equine Genome: Lessons From Encode, Sichong Peng, Jessica L. Petersen, Rebecca R. Bellone, Theodore S. Kalbfleisch, N. B. Kingsley, Alexa M. Barber, Eleonora Cappelletti, Elena Giulotto, Carrie J. Finno
Veterinary Science Faculty Publications
The horse reference genome assemblies, EquCab2.0 and EquCab3.0, have enabled great advancements in the equine genomics field, from tools to novel discoveries. However, significant gaps of knowledge regarding genome function remain, hindering the study of complex traits in horses. In an effort to address these gaps and with inspiration from the Encyclopedia of DNA Elements (ENCODE) project, the equine Functional Annotation of Animal Genome (FAANG) initiative was proposed to bridge the gap between genome and gene expression, providing further insights into functional regulation within the horse genome. Three years after launching the initiative, the equine FAANG group has generated data …
Evaluating Large Spontaneous Deletions In A Bovine Cell Line Selected For Bovine Viral Diarrhea Virus Resistance, Aspen M. Workman, Michael P. Heaton, Dennis A. Webster, Gregory P. Harhay, Theodore S. Kalbfleisch, Timothy P. L. Smith, Shollie M. Falkenberg, Daniel F. Carlson, Tad S. Sonstegard
Evaluating Large Spontaneous Deletions In A Bovine Cell Line Selected For Bovine Viral Diarrhea Virus Resistance, Aspen M. Workman, Michael P. Heaton, Dennis A. Webster, Gregory P. Harhay, Theodore S. Kalbfleisch, Timothy P. L. Smith, Shollie M. Falkenberg, Daniel F. Carlson, Tad S. Sonstegard
Maxwell H. Gluck Equine Research Center Faculty Publications
Bovine viral diarrhea virus’s (BVDV) entry into bovine cells involves attachment of virions to cellular receptors, internalization, and pH-dependent fusion with endosomal membranes. The primary host receptor for BVDV is CD46; however, the complete set of host factors required for virus entry is unknown. The Madin-Darby bovine kidney (MDBK) cell line is susceptible to BVDV infection, while a derivative cell line (CRIB) is resistant at the level of virus entry. We performed complete genome sequencing of each to identify genomic variation underlying the resistant phenotype with the aim of identifying host factors essential for BVDV entry. Three large compound deletions …
Pharmacokinetics Of Orally Administered Prednisolone In Alpacas, Ricardo Videla, Carla Sommardahl, Joseph Smith, Deanna M.W. Schaeffer, Sherry Cox
Pharmacokinetics Of Orally Administered Prednisolone In Alpacas, Ricardo Videla, Carla Sommardahl, Joseph Smith, Deanna M.W. Schaeffer, Sherry Cox
Faculty Publications and Other Works -- Large Animal Clinical Sciences
This study aimed to determine the pharmacokinetics of prednisolone following intravenous and oral administration in healthy adult alpacas. Healthy adult alpacas were given prednisolone (IV, n = 4), as well as orally (PO, n = 6). Prednisolone was administered IV once (1 mg/kg). Oral administration was once daily for 5 days (2 mg/kg). Each treatment was separated by a minimum 4 month washout period. Samples were collected at 0 (pre-administration), 0.083, 0.167, 0.25, 0.5, 0.75, 1, 2, 4, 8, 12, and 24 h after IV administration, and at 0 (pre-administration), 0.25, 0.5, 0.75, 1, 2, 4, 8, 12, 24 after …
Inheritance Of A Mutation Causing Neuropathy With Splayed Forelimbs In Jersey Cattle, A. Al-Khudhair, D. J. Null, J. B. Cole, C. W. Wolfe, David J. Steffen, P. M. Vanraden
Inheritance Of A Mutation Causing Neuropathy With Splayed Forelimbs In Jersey Cattle, A. Al-Khudhair, D. J. Null, J. B. Cole, C. W. Wolfe, David J. Steffen, P. M. Vanraden
School of Veterinary and Biomedical Sciences: Faculty Publications
A new undesirable genetic factor, neuropathy with splayed forelimbs (JNS), has been identified recently in the Jersey breed. Calves affected with JNS are unable to stand on splayed forelimbs that exhibit significant extensor rigidity and excessive lateral abduction at birth. Affected calves generally are alert at birth but exhibit neurologic symptoms, including spasticity of head and neck and convulsive behavior. Other symptoms reported include dislocated shoulders, congenital craniofacial anomalies, and degenerative myelopathy. Inheritance of an undesirable genetic factor was determined from a study of 16 affected calves reported by Jersey breeders across the United States. All of their pedigrees traced …
The Novel Orfv Protein Orfv113 Activates Lpa-P38 Signaling, Sushil Khatiwad, Gustavo Delho, Sabal Chaulagai, Daniel L. Rock
The Novel Orfv Protein Orfv113 Activates Lpa-P38 Signaling, Sushil Khatiwad, Gustavo Delho, Sabal Chaulagai, Daniel L. Rock
School of Veterinary and Biomedical Sciences: Faculty Publications
Viruses have evolved mechanisms to subvert critical cellular signaling pathways that regulate a wide range of cellular functions, including cell differentiation, proliferation and chemotaxis, and innate immune responses. Here, we describe a novel ORFV protein, ORFV113, that interacts with the G protein-coupled receptor Lysophosphatidic acid receptor 1 (LPA1). Consistent with its interaction with LPA1, ORFV113 enhances p38 kinase phosphorylation in ORFV infected cells in vitro and in vivo, and in cells transiently expressing ORFV113 or treated with soluble ORFV113. Infection of cells with virus lacking ORFV113 (OVIA82Δ113) significantly decreased p38 phosphorylation and viral plaque size. …
Adaptation Of An Artificial Bait To An Automated Aerial Delivery System For Landscape-Scale Brown Treesnake Suppression, Rafael A. Garcia, Thomas W. Mcauliffe, Lorelie P. Bumanlag, Shane R. Siers, Bruce A. Kimball
Adaptation Of An Artificial Bait To An Automated Aerial Delivery System For Landscape-Scale Brown Treesnake Suppression, Rafael A. Garcia, Thomas W. Mcauliffe, Lorelie P. Bumanlag, Shane R. Siers, Bruce A. Kimball
USDA Wildlife Services: Staff Publications
Dead neonatal mice are currently used as bait for delivery of toxin to invasive brown treesnakes (Boiga irregularis) on Guam; once deployed in the field the mice are highly attractive to the snakes but only for about four days. An artificial bait containing a mixture of fats mimicking those in skin of the mice is also highly attractive to the snakes and remains attractive 2–3 times longer. The artificial bait, however, costs more than the mice, and is more difficult to attach to the capsules of a novel aerial bait delivery system. This paper describes a reformulation of the bait …
Threading The Needle: How Humans Influence Predator–Prey Spatiotemporal Interactions In A Multiple-Predator System, Asia Murphy, Duane R. Diefenbach, Mark Ternent, Matt Lovallo, David Miller
Threading The Needle: How Humans Influence Predator–Prey Spatiotemporal Interactions In A Multiple-Predator System, Asia Murphy, Duane R. Diefenbach, Mark Ternent, Matt Lovallo, David Miller
USDA Wildlife Services: Staff Publications
Perceived predation risk and the resulting antipredator behaviour varies across space, time and predator identity. Communities with multiple predators that interact and differ in their use of space, time of activity and hunting mode create a complex landscape for prey to avoid predation. Anthropogenic presence and disturbance have the potential to shift interactions among predators and prey and the where and when encounters occur. We examined how white-tailed deer Odocoileus virginianus fawn spatiotemporal antipredator behaviour differed along an anthropogenic disturbance gradient that had black bears Ursus americanus, coyotes Canis latrans, bobcats Lynx rufus and humans present. We quantified (a) spatial …
Variations, Validations, Degradations, And Noninvasive Determination Of Pregnancy Using Fecal Steroid Metabolites In Free-Ranging Pronghorn, Cole A. Bleke, Eric M. Gese, Susannah S. French
Variations, Validations, Degradations, And Noninvasive Determination Of Pregnancy Using Fecal Steroid Metabolites In Free-Ranging Pronghorn, Cole A. Bleke, Eric M. Gese, Susannah S. French
USDA Wildlife Services: Staff Publications
Pregnancy status is a key parameter used to assess reproductive performance of a species as it represents a starting point for measuring vital rates. Vital rates allow managers to determine trends in populations such as neonate survival and recruitment; two important factors in ungulate population growth rates. Techniques to determine pregnancy have generally involved capture and restraint of the animal to obtain blood samples for determining serum hormone levels. Non-invasive pregnancy assessment, via feces, eliminates any hazards between handler and animal, as well as removes handling-induced physiological biases. Using noninvasive fecal sampling, we conducted hormone validations, investigated pregnancy rates, and …
Satellite-Detected Ammonia Changes In The United States: Natural Or Anthropogenic Impacts, Yaqian He, Rongting Xu, Stephen A. Prior, Di Yang, Anni Yang, Jian Chen
Satellite-Detected Ammonia Changes In The United States: Natural Or Anthropogenic Impacts, Yaqian He, Rongting Xu, Stephen A. Prior, Di Yang, Anni Yang, Jian Chen
USDA Wildlife Services: Staff Publications
Ammonia (NH3) is the most abundant alkaline component and can react with atmospheric acidic species to form aerosols that can lead to numerous environmental and health issues. Increasing atmospheric NH3 over agricultural regions in the US has been documented. However, spatiotemporal changes of NH3 concentrations over the entire US are still not thoroughly understood, and the factors that drive these changes remain unknown. Herein, we applied the Atmospheric Infrared Sounder (AIRS) monthly NH3 dataset to explore spatiotemporal changes in atmospheric NH3 and the empirical relationships with synthetic N fertilizer application, livestock manure production, and climate factors across the entire US …
Cytoarchitectural Characteristics Associated With Cognitive Flexibility In Raccoons, Joanna Jacob, Molly Kent, Sarah Benson-Amram, Suzana Herculano-Houzel, Mary Ann Raghanti, Emily Ploppert, Jack Drake, Bilal Hindi, Nick R. Natale, Sarah Daniels, Rachel Fanelli, Anderson Miller, Tim Landis, Amy Gilbert, Shylo Johnson, Annie Lai, Molly Hyer, Amanda Rzucidlo, Chris Anchor, Stan Gehrt, Kelly Lambert
Cytoarchitectural Characteristics Associated With Cognitive Flexibility In Raccoons, Joanna Jacob, Molly Kent, Sarah Benson-Amram, Suzana Herculano-Houzel, Mary Ann Raghanti, Emily Ploppert, Jack Drake, Bilal Hindi, Nick R. Natale, Sarah Daniels, Rachel Fanelli, Anderson Miller, Tim Landis, Amy Gilbert, Shylo Johnson, Annie Lai, Molly Hyer, Amanda Rzucidlo, Chris Anchor, Stan Gehrt, Kelly Lambert
USDA Wildlife Services: Staff Publications
With rates of psychiatric illnesses such as depression continuing to rise, additional preclinical models are needed to facilitate translational neuroscience research. In the current study, the raccoon (Procyon lotor) was investigated due to its similarities with primate brains, including comparable proportional neuronal densities, cortical magnification of the forepaw area, and cortical gyrification. Specifically, we report on the cytoarchitectural characteristics of raccoons profiled as high, intermediate, or low solvers in a multiaccess problem-solving task. Isotropic fractionation indicated that high-solvers had significantly more cells in the hippocampus (HC) than the other solving groups; further, a nonsignificant trend suggested that this …
Movement, Space-Use And Resource Preferences Of European Golden Jackals In Human-Dominated Landscapes: Insights From A Telemetry Study, Skye Fenton, Paul R. Moorcroft, Duško Ćirović, József Lanszki, Miklós Heltai, Francesca Cagnacci, Stewart Breck, Neda Bogdanović, Ilija Pantelić, Kornél Ács, Nathan Ranc
Movement, Space-Use And Resource Preferences Of European Golden Jackals In Human-Dominated Landscapes: Insights From A Telemetry Study, Skye Fenton, Paul R. Moorcroft, Duško Ćirović, József Lanszki, Miklós Heltai, Francesca Cagnacci, Stewart Breck, Neda Bogdanović, Ilija Pantelić, Kornél Ács, Nathan Ranc
USDA Wildlife Services: Staff Publications
During the last half-century, the distribution of golden jackals (Canis aureus) has rapidly increased throughout Europe. Today, golden jackals are thriving in human-dominated landscapes across Southeastern and Central Europe. Most studies on golden jackals have focused on large-scale distribution patterns; to date, little is known about the species’ fine-scale spatial ecology. In this study, we analyzed the movement behavior, space-use and resource selection of six golden jackals fitted with GPS-GSM collars in two study areas in Hungary and Serbia. Two of the jackals were a breeding pair. We found that home range size averaged 11.2 km2 (90% …
Effects Of Translocation On Survival Of Nuisance Bears, Javan Bauder, D. Ruid, N. M. Roberts, B. Kohn, M. L. Allen
Effects Of Translocation On Survival Of Nuisance Bears, Javan Bauder, D. Ruid, N. M. Roberts, B. Kohn, M. L. Allen
USDA Wildlife Services: Staff Publications
Effective mitigation of human–wildlife conflict should aim to reduce conflicts while also minimizing wildlife mortality. Translocation is often used to mitigate human–wildlife conflict but translocated individuals may have reduced survival, which could negatively affect population growth and social acceptance of translocation as a management tool. Yet, non-translocated nuisance individuals may also have low survival due to inherent risks associated with nuisance behavior. We used a 38-year dataset of 1233 marked and translocated nuisance American black bears (Ursus americanus) as a model system with which to evaluate the impacts of translocation on nuisance bear survival. We used multi-state mark-recapture models to …