Open Access. Powered by Scholars. Published by Universities.®
- Keyword
- Publication
-
- Other Publications in Zoonotics and Wildlife Disease (27)
- School of Veterinary and Biomedical Sciences: Faculty Publications (10)
- Michigan Bovine Tuberculosis Bibliography and Database (5)
- Veterinary Science Faculty Patents (1)
- Veterinary and Biomedical Sciences -- Department Information and History (1)
Articles 1 - 30 of 44
Full-Text Articles in Medicine and Health Sciences
Appendices, Glossary, And Index (Field Manual Of Wildlife Diseases)
Appendices, Glossary, And Index (Field Manual Of Wildlife Diseases)
Other Publications in Zoonotics and Wildlife Disease
A. Sample specimen history form
B. Sources of wildlife diagnostic assistance in the United States
C. Sources of supplies used for collecting, preserving, and shipping specimens
D. Normal brain cholinesterase activity values
E. Common and scientific names of birds in text
F. Common and scientific names other than birds
G. Chemical names
H. Conversion table
Glossary
Index
REPORT DOCUMENTATION PAGE
Parasites And Parisitic Diseases (Field Manual Of Wildlife Diseases), Rebecca A. Cole, Milton Friend
Parasites And Parisitic Diseases (Field Manual Of Wildlife Diseases), Rebecca A. Cole, Milton Friend
Other Publications in Zoonotics and Wildlife Disease
Parasitism is an intimate relationship between two different species in which one (parasite) uses the other (host) as its environment from which it derives nourishment. Parasites are a highly diverse group of organisms that have evolved different strategies for infecting their hosts. Some, such as lice and ticks, are found on the external parts of the body (ectoparasites), but most are found internally (endoparasites). Some are microscopic, such as the blood protozoans that cause avian malaria; however, many are macroscopic. Life cycles differ greatly between major types of parasites and are generally classified as direct or indirect (Table 1). Direct …
Miscellaneous Diseases (Field Manual Of Wildlife Diseases), Milton Friend, Nancy J. Thomas
Miscellaneous Diseases (Field Manual Of Wildlife Diseases), Milton Friend, Nancy J. Thomas
Other Publications in Zoonotics and Wildlife Disease
The fact that “Nature is far from benign” is clearly evident from the preceding chapters of this Manual. The diseases and other conditions described are the proverbial “tip of the iceberg” relative to the number of specific causes of ill health and death for free-ranging wild birds, but the wild bird health problems described account for most major wild bird disease conditions seen within the United States. However, the full toll from disease involves many other causes of illness and death that individually may cause substantial die-offs. Two examples of these other causes of die-offs are the deaths of Canada …
Field Manual Of Wildlife Diseases: General Field Procedures And Diseases Of Birds, Milton Friend, J. Christian Franson
Field Manual Of Wildlife Diseases: General Field Procedures And Diseases Of Birds, Milton Friend, J. Christian Franson
Other Publications in Zoonotics and Wildlife Disease
The “Field Manual of Wildlife Diseases: General Field Procedures and Diseases of Birds” presents practical, current information and insights about wild bird illnesses and the procedures to follow when ill birds are found or epidemics occur. Section 1 of the Manual provides information about general field procedures. Sections 2 through 5 describe various bird diseases. Sections 6 and 7 provide information about toxins that affect birds, and Section 8 describes miscellaneous diseases and hazards that affect birds. Manual lists institutions and laboratories that offer diagnostic services; sources of supplies for collecting, preserving, and shipping specimens; and it contains color illustrations …
The Latency-Related Gene Of Bovine Herpesvirus 1 Inhibits Programmed Cell Death, Janice Ciacci-Zanella, Melissa Stone, Gail A. Henderson, Clinton J. Jones
The Latency-Related Gene Of Bovine Herpesvirus 1 Inhibits Programmed Cell Death, Janice Ciacci-Zanella, Melissa Stone, Gail A. Henderson, Clinton J. Jones
School of Veterinary and Biomedical Sciences: Faculty Publications
Although viral gene expression occurs in the peripheral nervous system during acute infection, bovine herpesvirus 1 (BHV-1) gene expression is extinguished, many neurons survive, and latency ensues. The only abundant viral transcript expressed during latency is the latency-related (LR) RNA, which is alternatively spliced in trigeminal ganglia during acute infection (L. Devireddy and C. Jones, J. Virol. 72:7294–7301, 1998). A subset of neurons express a protein encoded by the LR gene and the LR protein (LRP) is associated with cyclin-dependent kinase 2 (Cdk2)/cyclin complexes during productive infection (Y. Jiang, A. Hossain, M. T. Winkler, T. Holt, A. Doster, and C. …
Introduction, Foreword, Table Of Contents (Field Manual Of Wildlife Diseases)
Introduction, Foreword, Table Of Contents (Field Manual Of Wildlife Diseases)
Other Publications in Zoonotics and Wildlife Disease
Cover
credits
Title page
Foreword by Thomas M. Yuill
Introduction by Milton Friend
Table of Contents
Chemical Toxins (Field Manual Of Wildlife Diseases), Milton Friend
Chemical Toxins (Field Manual Of Wildlife Diseases), Milton Friend
Other Publications in Zoonotics and Wildlife Disease
Many kinds of potentially harmful chemicals are found in environments used by wildlife. Some chemicals, such as pesticides and polychlorinated biphenyls (PCBs), are synthetic compounds that may become environmental contaminants through their use and application. Other materials, such as selenium and salt, are natural components of some environments, but contaminants of others. Natural and synthetic materials may cause direct poisoning and death, but they also may have adverse effects on wildlife that impair certain biological systems, such as the reproductive and immune systems. This section provides information about some of the environmental contaminants and natural chemicals that commonly cause avian …
Viral Diseases (Field Manual Of Wildlife Diseases), Douglas E. Docherty
Viral Diseases (Field Manual Of Wildlife Diseases), Douglas E. Docherty
Other Publications in Zoonotics and Wildlife Disease
Historically, viral diseases have not been recognized as major causes of illness and death in North American wild birds. Until relatively recently, this may have been due to inadequate technology to culture and identify these organisms. Unlike bacteria, viruses are too small to be seen under the light microscope and they cannot be grown on artificial media. Nevertheless, studies of infectious diseases caused by viruses have often predated discovery of the causative agents by many years as evidenced by smallpox immunizations being used centuries before that virus was identified. The isolations of a tobacco mosaic virus in 1892 and foot …
Bacterial Diseases (Field Manual Of Wildlife Diseases), Milton Friend
Bacterial Diseases (Field Manual Of Wildlife Diseases), Milton Friend
Other Publications in Zoonotics and Wildlife Disease
Diseases caused by bacteria are a more common cause of mortality in wild birds than are those caused by viruses. In addition to infection, some bacteria cause disease as a result of potent toxins that they produce. Bacteria of the genus Clostridium are responsible for more wild bird deaths than are other disease agents. Clostridium botulinum, which causes avian botulism, is primarily a form of food poisoning and it is included within the section on biotoxins (see Chapter 38). Other Clostridium sp. that colonize intestinal tissues produce toxins that cause severe hemorrhaging of the intestine, thus leading to tissue …
Fungal Diseases (Field Manual Of Wildlife Diseases), Milton Friend
Fungal Diseases (Field Manual Of Wildlife Diseases), Milton Friend
Other Publications in Zoonotics and Wildlife Disease
Fungi are important causes of disease in wild birds and other species. Three basic types of disease are caused by these agents: mycosis, or the direct invasion of tissues by fungal cells, such as aspergillosis; allergic disease involving the development of a hypersensitivity of the host to fungal antigens; and mycotoxicosis, which results from ingestion of toxic fungal metabolites. Mycosis and allergic disease may occur together, especially when the lung is infected. This section will address only mycosis. Mycotoxicosis is addressed in Section 6, Biotoxins. Allergic disease is not well studied in wild birds and it is beyond the scope …
Biotoxins (Field Manual Of Wildlife Diseases), Tonie E. Rocke, Milton Friend
Biotoxins (Field Manual Of Wildlife Diseases), Tonie E. Rocke, Milton Friend
Other Publications in Zoonotics and Wildlife Disease
Biotoxins are usually defined as poisons that are produced by and derived from the cells or secretions of living organisms. These natural poisons include some of the most toxic agents known and they are found within a wide variety of life forms. Organisms that produce such toxins are generally classified as being venomous or poisonous. The classification of venomous is usually associated with animal life forms such as poisonous reptiles and insects that have highly developed cellular mechanisms for toxin production and that deliver their toxins during a biting (rattlesnake) or stinging (black widow spider) act. Poisonous organisms are generally …
Introduction To General Field Procedures (Field Manual Of Wildlife Diseases), J. Christian Franson, Milton Friend, Dale E. Toweill, Robert L. Brownell Jr., Victor F. Nettles, Donald S. Davis, William J. Foreyt
Introduction To General Field Procedures (Field Manual Of Wildlife Diseases), J. Christian Franson, Milton Friend, Dale E. Toweill, Robert L. Brownell Jr., Victor F. Nettles, Donald S. Davis, William J. Foreyt
Other Publications in Zoonotics and Wildlife Disease
Section 1 of the Manual provides basic information regarding general field procedures for responding to wildlife disease events. Field biologists provide a critical linkage in disease diagnostic work and greatly affect the outcome of the laboratory efforts by the quality of the materials and information that they provide. The chapters in this section are oriented towards providing guidance that will assist field biologists in gathering the quality of information and specimens that are needed. Readers will find information regarding what to record and how; guidance for specimen collection, preservation, and shipment; and how to apply euthanasia when such actions are …
Bovine Herpesvirus 1 Can Infect Cd4+ T Lymphocytes And Induce Programmed Cell Death During Acute Infection Of Cattle, M. T. C. Winkler, Alan R. Doster, Clinton J. Jones
Bovine Herpesvirus 1 Can Infect Cd4+ T Lymphocytes And Induce Programmed Cell Death During Acute Infection Of Cattle, M. T. C. Winkler, Alan R. Doster, Clinton J. Jones
School of Veterinary and Biomedical Sciences: Faculty Publications
Acute infection of cattle with bovine herpesvirus 1 (BHV-1) represses cell-mediated immunity, which can lead to secondary bacterial infections. Since BHV-1 can induce apoptosis of cultured lymphocytes, we hypothesized that these virus-host interactions occur in cattle. To test this hypothesis, we analyzed lymph nodes and peripheral blood mononuclear cells (PBMC) after calves were infected with BHV-1. In situ terminal deoxynucleotidyltransferase- mediated dUTP nick end-labeling (TUNEL) staining of lymphoid tissues (pharyngeal tonsil, cervical, retropharyngeal, and inguinal) was used to detect apoptotic cells. Calves infected with BHV-1 for 7 days revealed increased apoptotic cells near the corticomedullary junction in lymphoid follicles and …
Isolation Of Cilia-Associated Respiratory (Car) Bacillus From Pigs And Calves And Experimental Infection Of Gnotobiotic Pigs And Rodents, Jerome C. Nietfeld, Barry L. Fickbohm, Douglas G. Rogers, Craig L. Franklin, Lela K. Riley
Isolation Of Cilia-Associated Respiratory (Car) Bacillus From Pigs And Calves And Experimental Infection Of Gnotobiotic Pigs And Rodents, Jerome C. Nietfeld, Barry L. Fickbohm, Douglas G. Rogers, Craig L. Franklin, Lela K. Riley
School of Veterinary and Biomedical Sciences: Faculty Publications
Filamentous, gram-negative bacteria morphologically similar to cilia-associated respiratory (CAR) bacillus of rodents and rabbits were isolated from the tracheas of 5 pigs and 4 calves. All pigs but none of the calves had histologic lesions of chronic tracheitis. In silver-stained histologic sections, CAR bacilli were adhered to the tracheal epithelium of each pig but were not found in the calves. Like CAR bacillus of rats, the bacteria displayed gliding motility and grew only in cell culture or cell culture medium supplemented with fetal serum. Initially, all isolates were contaminated by Mycoplasma spp. This contamination was eliminated from 4 pig isolates …
An Investigation Into The Possibility Of Transmission Of Tick-Borne Pathogens Via Blood Transfusion, P. M. Arguin, J. Singleton, L. D. Rotz, E. Marston, T. A. Treadwell, K. Slater, M. Chamberland, A. Schwartz, A. Tengelsen, J. G. Olson, J. E. Childs, Transfusion-Associated Tick-Borne Illness Task Force
An Investigation Into The Possibility Of Transmission Of Tick-Borne Pathogens Via Blood Transfusion, P. M. Arguin, J. Singleton, L. D. Rotz, E. Marston, T. A. Treadwell, K. Slater, M. Chamberland, A. Schwartz, A. Tengelsen, J. G. Olson, J. E. Childs, Transfusion-Associated Tick-Borne Illness Task Force
Other Publications in Zoonotics and Wildlife Disease
STUDY DESIGN AND METHODS: Donors and recipients were asked to complete questionnaires regarding symptoms and risk factors for infection and to provide blood samples for laboratory analysis.
RESULTS: Among National Guard personnel who donated blood, 12 individuals were found to have a confirmed or probable case of Rocky Mountain spotted fever or ehrlichiosis. A total of 320 units (platelets or packed red cells) from 377 donors were transfused into 129 recipients. Although 10 recipients received units from National Guard personnel with confirmed or probable infection, none became ill.
CONCLUSION: Transfusion-transmitted illness did not occur. Despite the awareness of the risk …
Optimal Replication Activity Of Vesicular Stomatitis Virus Rna Polymerase Requires Phosphorylation Of A Residue(S) At Carboxy-Terminal Domain Ii Of Its Accessory Subunit, Phosphoprotein P, Leroy N. Hwang, Nathan Englund, Tapas Das, Amiya K. Florida, Asit K. Pattnaik
Optimal Replication Activity Of Vesicular Stomatitis Virus Rna Polymerase Requires Phosphorylation Of A Residue(S) At Carboxy-Terminal Domain Ii Of Its Accessory Subunit, Phosphoprotein P, Leroy N. Hwang, Nathan Englund, Tapas Das, Amiya K. Florida, Asit K. Pattnaik
School of Veterinary and Biomedical Sciences: Faculty Publications
The phosphoprotein, P, of vesicular stomatitis virus (VSV) is a key subunit of the viral RNA-dependent RNA polymerase complex. The protein is phosphorylated at multiple sites in two different domains. We recently showed that specific serine and threonine residues within the amino-terminal acidic domain I of P protein must be phosphorylated for in vivo transcription activity, but not for replication activity, of the polymerase complex. To examine the role of phosphorylation of the carboxy-terminal domain II residues of the P protein in transcription and replication, we have used a panel of mutant P proteins in which the phosphate acceptor sites …
Activation Of Caspases And P53 By Bovine Herpesvirus 1 Infection Results In Programmed Cell Death And Efficient Virus Release, Laxminarayana R. Devireddy, Clinton J. Jones
Activation Of Caspases And P53 By Bovine Herpesvirus 1 Infection Results In Programmed Cell Death And Efficient Virus Release, Laxminarayana R. Devireddy, Clinton J. Jones
School of Veterinary and Biomedical Sciences: Faculty Publications
Programmed cell death (PCD), or apoptosis, is initiated in response to various stimuli, including virus infection. Bovine herpesvirus 1 (BHV-1) induces PCD in peripheral blood mononuclear cells at the G0/G1 phase of the cell cycle (E. Hanon, S. Hoornaert, F. Dequiedt, A. Vanderplasschen, J. Lyaku, L. Willems, and P.-P. Pastoret, Virology 232:351–358, 1997). However, penetration of virus particles is not required for PCD (E. Hanon, G. Meyer, A. Vanderplasschen, C. Dessy-Doize, E. Thiry, and P. P. Pastoret, J. Virol. 72:7638–7641, 1998). The mechanism by which BHV-1 induces PCD in peripheral blood mononuclear cells is not understood, nor …
Formulations And Methods To Treat And Prevent Equine Protozoal Myeloencephalitis, David E. Granstrom, Thomas Tobin
Formulations And Methods To Treat And Prevent Equine Protozoal Myeloencephalitis, David E. Granstrom, Thomas Tobin
Veterinary Science Faculty Patents
The present invention provides formulations useful to treat EPM. It also provides methods to treat EPM in a horse in need of such treatment, comprising administering a pharmaceutically effective amount of a triazine-based anti-coccidial. Preferred are methods to treat EPM using clazuril, diclazuril, toltrazuril or letrazuril. The present invention also provides methods to prevent S. neurona infection in horses comprising administering a prophylactic amount of a triazine-based anticoccidial. Preferred is a method to prevent S. neurona infection by using clazuril, diclazuril, toltrazuril or letrazuril, alone or in combination with other known therapeutics.
Nucleotide Sequences For Detection Of Serpulina Hyodysenteriae, Gerald E. Duhamel, Robert Elder
Nucleotide Sequences For Detection Of Serpulina Hyodysenteriae, Gerald E. Duhamel, Robert Elder
School of Veterinary and Biomedical Sciences: Faculty Publications
The invention provides a method for detecting the presence of Serpulina hyOdysenteriae in a biological Sample, an oligonucleotide primer and an S. hyodysenteriae-specific oligonucleotide probe useful in that method, and an article of manufacture that contains the primers and/or probe. Also provided are an about 2.3-kb DNA fragment derived from genomic DNA of S. hyodysenteriae and encoding for an about 56 kDa polypeptide, a recombinant expression vector containing the DNA fragment, the 56 kDa polypeptide and a monoclonal antibody reactive with the peptide, and a method of assaying for antibodies reactive with the 56 kDa peptide.
Development Of A Firefly Luciferase-Based Assay For Determining Antimicrobial Susceptibility Of Mycobacterium Avium Subsp. Paratuberculosis, Stephanie L. Williams, N. Beth Harris, Raul G. Barletta
Development Of A Firefly Luciferase-Based Assay For Determining Antimicrobial Susceptibility Of Mycobacterium Avium Subsp. Paratuberculosis, Stephanie L. Williams, N. Beth Harris, Raul G. Barletta
School of Veterinary and Biomedical Sciences: Faculty Publications
Paratuberculosis (Johne’s disease) is a fatal disease of ruminants for which no effective treatment is available. Presently, no drugs against Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis), the causative agent of Johne’s disease, are approved for use in livestock. Additionally, M. paratuberculosis has been linked to a human chronic granulomatous ileitis (Crohn’s disease). To assist in the evaluation of antimicrobial agents with potential activity against M. paratuberculosis, we have developed a firefly luciferase-based assay for the determination of drug susceptibilities. The microorganism used was M. paratuberculosis K-10(pYUB180), a clinical isolate carrying a plasmid with the firefly luciferase gene. …
Bovine Tuberculosis Eradication: Uniform Methods And Rules, Effective January 22, 1999
Bovine Tuberculosis Eradication: Uniform Methods And Rules, Effective January 22, 1999
Michigan Bovine Tuberculosis Bibliography and Database
These Uniform Methods and Rules (UMR) are the minimum standards adopted and approved by the Deputy Administrator, Veterinary Services (VS), Animal and Plant Health Inspection Service (APHIS), on January 21, 1999. They were established for the maintenance of tuberculosis-free accredited herds of cattle, captive cervids, bison, and goats, and the maintenance of State status in the U.S. Department of Agriculture’s tuberculosis eradication program.
These minimum standards do not preclude the adoption of more stringent standards by any State, status zone within a State, or region containing multiple States.
Family Cluster Of Rocky Mountain Spotted Fever, James E. Childs, Timothy F. Jones, Allen S. Craig, Christopher D. Paddock, Don B. Mckechnie, Sherif R. Zaki, William Schaffner
Family Cluster Of Rocky Mountain Spotted Fever, James E. Childs, Timothy F. Jones, Allen S. Craig, Christopher D. Paddock, Don B. Mckechnie, Sherif R. Zaki, William Schaffner
Other Publications in Zoonotics and Wildlife Disease
Soon after a patient from Tennessee died of Rocky Mountain spotted fever (RMSF), several family members developed symptoms suggestive of the disease and were treated presumptively for RMSF. Fifty-four persons visiting the index patient's home were interviewed; serum samples were collected from 35. Three additional cases of RMSF were confirmed, all of which occurred in firstdegree relatives. Time spent at the family home and going into the surrounding woods were significantly associated with developing antibodies to Rickettsia rickettsii. Ticks were collected and examined for rickettsiae by polymerase chain reaction analysis. Because hyperendemic foci and family clusters of RMSF can …
Dusky-Footed Wood Rats (Neotoma Fuscipes) As Reservoirs Of Granulocytic Ehrlichiae (Rickettsiales: Ehrlichieae) In Northern California, William L. Nicholson, Martin B. Castro, Vicki L. Kramer, John W. Sumner, James E. Childs
Dusky-Footed Wood Rats (Neotoma Fuscipes) As Reservoirs Of Granulocytic Ehrlichiae (Rickettsiales: Ehrlichieae) In Northern California, William L. Nicholson, Martin B. Castro, Vicki L. Kramer, John W. Sumner, James E. Childs
Other Publications in Zoonotics and Wildlife Disease
Dusky-footed wood rats (Neotoma fuscipes) and Peromyscus sp. mice (P. maniculatus and P. truei) were collected from one site in Placer County, one site in Santa Cruz County, and two sites in Sonoma County in northern California. Serum or plasma samples from 260 rodents were tested for antibodies to the agent of human granulocytic ehrlichiosis. Of these, samples from 25 wood rats (34% of those tested) and 10 (8%) Peromyscus sp. mice were found to be seropositive, but only those from one site. PCR assays targeting the groESL heat shock operon were conducted on all seropositive …
Molecular Cloning And Characterization Of The Ehrlichia Chaffeensis Variable-Length Pcr Target: An Antigen-Expressing Gene That Exhibits Interstrain Variation, John W. Sumner, James E. Childs, Christopher D. Paddock
Molecular Cloning And Characterization Of The Ehrlichia Chaffeensis Variable-Length Pcr Target: An Antigen-Expressing Gene That Exhibits Interstrain Variation, John W. Sumner, James E. Childs, Christopher D. Paddock
Other Publications in Zoonotics and Wildlife Disease
A clone expressing an immunoreactive protein with an apparent molecular mass of 44 kDa was selected from an Ehrlichia chaffeensis Arkansas genomic library by probing with anti-E. chaffeensis hyperimmune mouse ascitic fluid. Nucleotide sequencing revealed an open reading frame (ORF) capable of encoding a 198-aminoacid polypeptide. The ORF contained four imperfect, direct, tandem 90-bp repeats. The nucleotide and deduced amino acid sequences did not show close homologies to entries in the molecular databases. PCR with primers whose sequences matched the sequences flanking the ORF was performed with DNA samples extracted from cell cultures infected with nine different isolates of E. …
Hidden Mortality Attributable To Rocky Mountain Spotted Fever: Immunohistochemical Detection Of Fatal, Serologically Unconfirmed Disease, James E. Childs, Patricia W. Greer, Tara L. Ferebee, Joseph Singleton Jr., Don B. Mckechnie, Tracee A. Treadwell, John W. Krebs, Matthew J. Clarke, Robert C. Holman, James G. Olson, Christopher D. Paddock, Sherif R. Zaki
Hidden Mortality Attributable To Rocky Mountain Spotted Fever: Immunohistochemical Detection Of Fatal, Serologically Unconfirmed Disease, James E. Childs, Patricia W. Greer, Tara L. Ferebee, Joseph Singleton Jr., Don B. Mckechnie, Tracee A. Treadwell, John W. Krebs, Matthew J. Clarke, Robert C. Holman, James G. Olson, Christopher D. Paddock, Sherif R. Zaki
Other Publications in Zoonotics and Wildlife Disease
Rocky Mountain spotted fever (RMSF) is the most severe tickborne infection in the United States and is a nationally notifiable disease. Since 1981, the annual case-fatality ratio for RMSF has been determined from laboratory-confirmed cases reported to the Centers for Disease Control and Prevention (CDC). Herein, a description is given of patients with fatal, serologically unconfirmed RMSF for whom a diagnosis of RMSF was established by immunohistochemical (IHC) staining of tissues obtained at autopsy. During 1996-1997, acute-phase serum and tissue samples from patients with fatal disease compatible with RMSF were tested at the CDC. As determined by indirect immunofluorescence assay, …
Population Dynamics Of A Naturally Occurring Heterogeneous Mixture Of Borrelia Burgdorferi Clones, Erick K. Hofmeister, Gregory E. Glass, James E. Childs, David H. Persing
Population Dynamics Of A Naturally Occurring Heterogeneous Mixture Of Borrelia Burgdorferi Clones, Erick K. Hofmeister, Gregory E. Glass, James E. Childs, David H. Persing
Other Publications in Zoonotics and Wildlife Disease
Two unique isolates of Borrelia burgdorferi, differing in plasmid content and outer surface protein C expression, were cultured on sequential captures of a single free-living Peromyscus leucopus mouse and were examined for differences in transmissibility. Both isolates were transmissible from inoculated C.B-17 mice to larval Ixodes scapularis ticks and, subsequently, from infected nymphal ticks to C3H/HeJ mice. Plasmid and protein analyses suggested that the original isolates were a mixed population of B. burgdorferi, and cloning by limiting dilution resulted in the identification of two clonal groups. In addition to being heterogeneous in plasmid and genomic macrorestriction analyses, the …
Isolation Of A New Subspecies, Bartonella Vinsonii Subsp. Arupensis, From A Cattle Rancher: Identity With Isolates Found In Conjunction With Borrelia Burgdorferi And Babesia Microti Among Naturally Infected Mice, David F. Welch, Karen C. Carroll, Erick K. Hofmeister, David H. Persing, Denise A. Robison, Arnold G. Steigerwalt, Don J. Brenner
Isolation Of A New Subspecies, Bartonella Vinsonii Subsp. Arupensis, From A Cattle Rancher: Identity With Isolates Found In Conjunction With Borrelia Burgdorferi And Babesia Microti Among Naturally Infected Mice, David F. Welch, Karen C. Carroll, Erick K. Hofmeister, David H. Persing, Denise A. Robison, Arnold G. Steigerwalt, Don J. Brenner
Other Publications in Zoonotics and Wildlife Disease
Bacteremia with fever due to a novel subspecies of Bartonella vinsonii was found in a cattle rancher. The subspecies shared major characteristics of the genus Bartonella in terms of most biochemical features and cellular fatty acid profile, but it was distinguishable from other subspecies of B. vinsonii by good growth on heart infusion agar supplemented with X factor and by its pattern of enzymatic hydrolysis of peptide substrates. DNA relatedness studies verified that the isolate belonged to the genus Bartonella and that it was genotypically related to B. vinsonii. The highest level of relatedness was observed with recently characterized …
Prp Genotypes Of Captive And Free-Ranging Rocky Mountain Elk (Cervus Elaphus Nelsoni) With Chronic Wasting Disease, Katherine I. O'Rourke, T. E. Besser, M. W. Miller, T. F. Cline, T. R. Spraker, A. L. Jenny, M. A. Wild, G. L. Zebarth
Prp Genotypes Of Captive And Free-Ranging Rocky Mountain Elk (Cervus Elaphus Nelsoni) With Chronic Wasting Disease, Katherine I. O'Rourke, T. E. Besser, M. W. Miller, T. F. Cline, T. R. Spraker, A. L. Jenny, M. A. Wild, G. L. Zebarth
Other Publications in Zoonotics and Wildlife Disease
The PrP gene encodes the putative causative agent of the transmissible spongiform encephalopathies (TSEs), a heterogeneous group of fatal, neurodegenerative disorders including human Creutzfeldt–Jakob disease, bovine spongiform encephalopathy, ovine scrapie and chronic wasting disease (CWD) of North American deer and elk. Polymorphisms in the PrP gene are associated with variations in relative susceptibility, pathological lesion patterns, incubation times and clinical course of TSEs of humans, mice and sheep. Sequence analysis of the PrP gene from Rocky Mountain elk showed only one amino acid change (Met to Leu at cervid codon 132). Homozygosity for Met at the corresponding polymorphic site (Met …
In Situ Hybridization For The Detection And Localization Of Swine Chlamydia Trachomatis, C. Chae, D.-S. Cheon, D. Kwon, O. Kim, B. Kim, J. Suh, D. G. Rogers, K. D. E. Everett, A. A. Anderson
In Situ Hybridization For The Detection And Localization Of Swine Chlamydia Trachomatis, C. Chae, D.-S. Cheon, D. Kwon, O. Kim, B. Kim, J. Suh, D. G. Rogers, K. D. E. Everett, A. A. Anderson
School of Veterinary and Biomedical Sciences: Faculty Publications
Gnotobiotic piglets were inoculated intralaryngeally with swine Chlamydia trachomatis strain R33 or orally with swine C. trachmatis strain R27. Archived formalin-fixed, paraffin-embedded tissues from piglets euthanatized 4–7 days postinoculation were examined by in situ hybridization for C. trachomatis nucleic acid using a nonradioactive digoxigenin-labeled DNA probes that targeted specific ribosomal RNA or omp1 mRNA molecules of the swine C. trachomatis strains. Positive hybridization signals were detected in bronchial epithelial cells, bronchiolar epithelial cells, pneumocytes, alveolar and interstitial macrophages, and jejunal and ileal enterocytes. Chlamydia-infected cells had a strong signal that was confined to the intracytoplasmic inclusions. Positive hybridization signals were …
Observations On Animal And Human Health During The Outbreak Of Mycobacterium Bovis In Game Farm Wapiti In Alberta, P. Nick Nation, E. Anne Fanning, H. Bim Hopf, Terry L. Church
Observations On Animal And Human Health During The Outbreak Of Mycobacterium Bovis In Game Farm Wapiti In Alberta, P. Nick Nation, E. Anne Fanning, H. Bim Hopf, Terry L. Church
Michigan Bovine Tuberculosis Bibliography and Database
This report describes and discusses the history, clinical, pathologic, epidemiologic, and human health aspects of an outbreak of Mycobacterium bovis infection in domestic wapiti in Alberta between 1990 and 1993, shortly after legislative changes allowing game farming. The extent and seriousness of the outbreak of M. bovis in wapiti in Alberta was not fully known at its onset. The clinical findings in the first recognized infected wapiti are presented and the postmortem records for the herd in which the animal resided are summarized. Epidemiologic findings from the subsequent field investigation are reviewed, the results of recognition and investigation of human …