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Veterinary Medicine

Mark R. Ackermann

1991

Swine

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Bronchiolar Metaplasia And Ulex Europaeus Agglutinin I (Uea-I) Affinity In Mycoplasma Hyopneumoniae-Infected Lungs Of Six Pigs, Mark R. Ackermann, M. C. Debey, B. M. Debey Nov 1991

Bronchiolar Metaplasia And Ulex Europaeus Agglutinin I (Uea-I) Affinity In Mycoplasma Hyopneumoniae-Infected Lungs Of Six Pigs, Mark R. Ackermann, M. C. Debey, B. M. Debey

Mark R. Ackermann

Mycoplasma hyopneumoniae adheres to the cilia and apical plasma membrane of cells that line the trachea, bronchi, and bron ch ioles. Colonization result s in ciliostasis and peribronchial and peribronchi olar nod ular aggregates of lymphocytes and plasma cells.">Altho ugh adhesion-receptor interaction s between the organism and respiratory epithelial cells have been examined, little attention has been given to the morphologic and phenotypic changes that may occur in cells lining bron chioles during infection. In this study, we describe morphologic cha nges and differenc es in lectin staining patt ern s in the bron chi oles from lungs of …


Colonization Of The Pharyngeal Tonsil And Respiratory Tract Of The Gnotobiotic Pig By A Toxigenic Strain Of Pasteurella Multocida Type D, Mark R. Ackermann, N. F. Cheville, J. E. Gallagher Jul 1991

Colonization Of The Pharyngeal Tonsil And Respiratory Tract Of The Gnotobiotic Pig By A Toxigenic Strain Of Pasteurella Multocida Type D, Mark R. Ackermann, N. F. Cheville, J. E. Gallagher

Mark R. Ackermann

Seven-day-old gnotobiotic pigs were inoculated intranasally with Pasteurella multocida and euthanatized 2, 5, 9, and 14 days after inoculation. Tissues from the oropharynx and respiratory tract of pigs were cultured quantitatively and analyzed microscopically. Pigs remained afebrile and alert, except one that died of acute fibrinopurulent pneumonia. Pasteurella multocida was isolated in greatest numbers from the pharyngeal tonsils, but only in low numbers from turbinate, trachea, lung, spleen, and liver. Significant histologic changes were limited to the tonsil. Infected pigs developed mild tonsillitis with lymphocytic hyperplasia, and accumulation of cell debris and bacteria in crypts. Capsular antigens of P. multocida, …