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Faculty Publications and Other Works -- Small Animal Clinical Sciences

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Urine Sodium Concentrations Are Predictive Of Hypoadrenocorticism In Hyponatremic Dogs: A Retrospective Pilot Study, Elizabeth More Lennon, Shelly L. Vaden Apr 2018

Urine Sodium Concentrations Are Predictive Of Hypoadrenocorticism In Hyponatremic Dogs: A Retrospective Pilot Study, Elizabeth More Lennon, Shelly L. Vaden

Faculty Publications and Other Works -- Small Animal Clinical Sciences

Abstract

OBJECTIVES:

To determine if a urine sodium concentration could be used to rule out hypoadrenocorticism in hyponatraemic dogs.

MATERIALS AND METHODS:

Medical records were reviewed for hyponatraemic dogs (serum sodium/L) that had recorded urine sodium concentrations. Twenty hyponatraemic dogs were included: 11 diagnosed with classical hypoadrenocorticism and nine with non-adrenal causes of hyponatraemia. A Wilcoxon rank-sum test was used to compare results between groups.

RESULTS:

No dog with hypoadrenocorticism had a urine sodium concentration less than 30 mmol/L. Urine sodium concentration in dogs with hypoadrenocorticism was significantly higher (median 103 mmol/L, range: 41 to 225) than in dogs with …