Medicine and Health Sciences Commons^™

Transcriptomic And Metabolomic Profiling Of Chicken Adipose Tissue In Response To Insulin Neutralization And Fasting, Bo Ji, Ben Ernest, Jessica R. Gooding, Suchita Das, Arnold M. Saxton, Jean Simon, Joelle Dupont, Sonia Métayer-Coustard, Shawn R. Campagna, Brynn H. Voy

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Background

Domestic broiler chickens rapidly accumulate adipose tissue due to intensive genetic selection for rapid growth and are naturally hyperglycemic and insulin resistant, making them an attractive addition to the suite of rodent models used for studies of obesity and type 2 diabetes in humans. Furthermore, chicken adipose tissue is considered as poorly sensitive to insulin and lipolysis is under glucagon control. Excessive fat accumulation is also an economic and environmental concern for the broiler industry due to the loss of feed efficiency and excessive nitrogen wasting, as well as a negative trait for consumers who are increasingly conscious of …

Does Place Of Residence Affect Risk Of Suicide? A Spatial Epidemiologic Investigation In Kentucky From 1999 To 2008, Daniel M. Saman, Sabrina Walsh, Anna Borówko, Agricola Odoi

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Background

Approximately 32,000 people take their own lives every year in the United States. In Kentucky, suicide mortality rates have been steadily increasing since 1999. Few studies in the United States have assessed spatial clustering of suicides. The purpose of this study was to identify high-risk clusters of suicide at the county level in Kentucky and assess the characteristics of those suicide cases within the clusters.

Methods

A spatial epidemiological study was undertaken using suicide data for the period January 1, 1999 to December 31, 2008, obtained from the Kentucky Office of Vital Statistics. Descriptive analyses using Pearson's chi-square test …

Socioeconomic Determinants Of Geographic Disparities In Campylobacteriosis Risk: A Comparison Of Global And Local Modeling Approaches, Jennifer Weisent, Barton Rohrbach, John R. Dunn, Agricola Odai

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Background

Socioeconomic factors play a complex role in determining the risk of campylobacteriosis. Understanding the spatial interplay between these factors and disease risk can guide disease control programs. Historically, Poisson and negative binomial models have been used to investigate determinants of geographic disparities in risk. Spatial regression models, which allow modeling of spatial effects, have been used to improve these modeling efforts. Geographically weighted regression (GWR) takes this a step further by estimating local regression coefficients, thereby allowing estimations of associations that vary in space. These recent approaches increase our understanding of how geography influences the associations between determinants and …

In Vitro Investigation Of A Terbinafine Impregnated Subcutaneous Implant For Veterinary Use, Marcy J. Souza, Tim Cairns, Jason Yarbrough, Sherry Cox

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

No abstract provided.