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Therapeutic Potential Of Bulgarian Propolis Against Antibiotic-Resistant Salmonella Species, Manar M. Farouk, Amal El-Molla, Fayez A. Salib, Yousef A. Soliman, Mohamed Shaalan
Therapeutic Potential Of Bulgarian Propolis Against Antibiotic-Resistant Salmonella Species, Manar M. Farouk, Amal El-Molla, Fayez A. Salib, Yousef A. Soliman, Mohamed Shaalan
The Thai Journal of Veterinary Medicine
The emergence of multidrug-resistant (MDR) Salmonella spp. has increased the need for investigation of antimicrobial alternatives. Ethanolic extract of propolis (EEP) has been identified to have wide-ranging medical applications related to its antimicrobial activity. The current study aimed to identify the major chemical components of EEP with antibacterial effects, evaluate the antibacterial efficacy of EEP against MDR Salmonella spp. isolates, and further examine the therapeutic efficacy of EEP against MDR S. Enteritidis infected mouse model. Bulgarian propolis EEP was prepared by using ethanol based extraction method. The chemical composition of EEP was characterized using the gas chromatography-mass spectroscopy (GC-MS). The …