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Full-Text Articles in Medicine and Health Sciences
Effects Of Benzyl Isothiocyanate And Papain On The Hatching And Migration Of Equine Cyathostomes, Jessie Kmietsch
Effects Of Benzyl Isothiocyanate And Papain On The Hatching And Migration Of Equine Cyathostomes, Jessie Kmietsch
Undergraduate Honors Thesis Projects
Cyathostomes are widespread and can affect horses of any life stage. Many common anthelmintics are no longer effective at treating cyathostomes due to parasitic resistance. The objective of this in vitrostudy was to use egg hatch and larval migration tests to determine if compounds found in papaya seeds (papain or benzyl isothiocyanate) reduce cyathostome egg hatching and migration. The experiments were conducted between August 2016 and March 2018. Cyathostome eggs were obtained from horse fecal samples. Egg hatch tests were performed by adding papain and benzyl isothiocyanate (BITC) to wells separately at different concentrations in triplicate. After incubation, the …
The Use Of Papain And Benzyl Isothiocyanate As Anthelmintics For Equine Strongyles, Abigail Maxey
The Use Of Papain And Benzyl Isothiocyanate As Anthelmintics For Equine Strongyles, Abigail Maxey
Undergraduate Honors Thesis Projects
Seeds of Carica papaya L. (Caricaceae) are a promising source of investigation for a novel anthelmintic to treat equine strongyle infestation. Strongyles are small redworms that attach to the intestinal wall in the equine. They can cause colic, poor hair coat, poor body condition, and, in severe cases, death. The objective of this study was to determine if benzyl isothiocyanate (BITC) and papain, two compounds found in papaya seeds, could be used to prevent migration of third stage cyathostome larvae (L3) in vitro using larval migration inhibition assays. The assays involved incubating larvae in solution, followed by larval migration through …