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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Surgery

2014

Zucker School of Medicine at Hofstra/Northwell

Cortical stimulation;; effective connectivity;; epilepsy;; evoked;; potentials;; Brodmann's areas;; INTRINSIC FUNCTIONAL ARCHITECTURE;; CORTICAL ELECTRICAL-STIMULATION;; TEMPORAL-LOBE EPILEPSY;; COMPLEX BRAIN NETWORKS;; LIVING HUMAN BRAIN;; GRANGER CAUSALITY;; CEREBRAL-CORTEX;; LANGUAGE SYSTEM;; MOTOR CORTEX;; IN-VIVO;; Neurosciences;; Neuroimaging;; Radiology

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Full-Text Articles in Medicine and Health Sciences

Evoked Effective Connectivity Of The Human Neocortex, L. Entz, E. Toth, C. J. Keller, S. Bickel, D. M. Groppe, D. Fabo, L. R. Kozak, L. Eross, I. Ulbert, A. D. Mehta Jan 2014

Evoked Effective Connectivity Of The Human Neocortex, L. Entz, E. Toth, C. J. Keller, S. Bickel, D. M. Groppe, D. Fabo, L. R. Kozak, L. Eross, I. Ulbert, A. D. Mehta

Journal Articles

The role of cortical connectivity in brain function and pathology is increasingly being recognized. While in vivo magnetic resonance imaging studies have provided important insights into anatomical and functional connectivity, these methodologies are limited in their ability to detect electrophysiological activity and the causal relationships that underlie effective connectivity. Here, we describe results of cortico-cortical evoked potential (CCEP) mapping using single pulse electrical stimulation in 25 patients undergoing seizure monitoring with subdural electrode arrays. Mapping was performed by stimulating adjacent electrode pairs and recording CCEPs from the remainder of the electrode array. CCEPs reliably revealed functional networks and showed an …