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Comparison Of Misoprostol Vs Dinoprostone In Induction Of Labour, Mofeed Fawzy Mohamed, Al-Refaai Abd El-Fattah Marai, Mahmoud Ebraheim Atia Othman

Al-Azhar International Medical Journal

Background; The practise of obstetrics includes labour induction on a regular basis. In contemporary obstetrics, it is primarily used when continuing a pregnancy could be harmful to the mother, the fetus, or both. Oxytocin infusion has historically been used to induce labor, although multiple studies have proven that when the cervix is unfavourable, it cannot offer as satisfying results, Aim and objectives: To compare effectiveness of Dinoprostone vaginal inserts versus Misoprostol vaginal inserts in induction of labor as regard mode of delivery, number of doses and induction active labour interval, and the safety of the mother as regard uterine hyperstimulation …

Comparative Study Between Oral And Vaginal Administration Of Misoprostol In The Induction Of Labour In Cases With Premature Rupture Of Membranes (Prom), Diaa Maged Fakhr, Ismael Talaat El-Garhy, Fahd Abdel-Aal Elomda, Hany Abdelhakim Abdelrahman, Nesreen Ahmed Mostafa Rashed

Al-Azhar International Medical Journal

Background: Cervical ripening is mediated by membrane-bound G-coupled receptor prostaglandins. Boost leukocyte extravasation and collagenase. Biochemical mechanisms alter the distribution of proteoglycan and collagen, allowing cervical effacement and dilatation. The use of PG gel for induction began in the 1980s. Prior to the 1990s, oral PG was avoided for induction of labour due to its unpleasant gastrointestinal effects. Oral route may improve mother satisfaction more than vaginal route. Aim: What is the difference between the effect of oral and vaginal misoprostol for induction of labor in pregnant females with PROM regarding efficacy, safety, maternal and fetal outcomes? Subject and Methods: …

Comparative Study Between The Effect Of Letrozole Prior To Misoprostol And Misoprostol Alone In Induction Of Abortion, Ashraf Hamdy Mohammed, Ahmed Mohammed Saeed, Ahmed Mostafa Yassin Ali

Al-Azhar International Medical Journal

Background: Missed abortions may be treated with a number of medicinal and surgical procedures. Surgical methods include vacuum aspiration and dilatation and curettage. Letrozole, aromatase inhibitor, binds to iron in P450 cytochrome in reversible & competitive manner, preventing aromatase from producing oestrogen. Aim: To compare impact of using letrozole before misoprostol in 1st trimester termination of non-viable pregnancy to use of misoprostol alone. Subject & techniques: This was prospective randomized clinical trial include 100 patients with history of missed abortion confirmed by ultrasonography at Al-Hussein Hospital & Al-Azhar University Cairo. Results: Curettage was significantly increased in group 1 compared with …

Misoprostol Prior To Elective Cesarean Section To Reduce Transient Tachypnea Of Newborn, Mohammed Fares Ibrahim Elnahas, Mofeed Fawzy Mohammed, Wael Solaiman Taha, Abdelsattar Abdullah Elsayeh

Al-Azhar International Medical Journal

Background: The danger of respiratory diseases in the newborn, such as respiratory distress syndrome, is increased when the mother chooses to have the baby before 39 weeks of gestation through an elective caesarean section. Prostaglandins are helpful for the developing lungs because they stimulate the release of the stress hormone catecholamines, which in turn increases the production of the protective molecule surfactant. Nonetheless, the efficacy of antenatal preventive injections of prostaglandin is still debatable in clinical practice.

Aim of the study: to assess the effectiveness of vaginal misoprostol in preventing transitory tachypnea in newborns prior to elective caesarean section.

Patients …