Medicine and Health Sciences Commons^™

Medical Marijuana And Opioids (Memo) Study: Protocol Of A Longitudinal Cohort Study To Examine If Medical Cannabis Reduces Opioid Use Among Adults With Chronic Pain, Chinazo O. Cunningham, Joanna L. Starrels, Chenshu Zhang, Marcus A. Bachhuber, Nancy L. Sohler, Frances R. Levin, Haruka Minami, Deepika E. Slawek, Julia H. Arnsten

School of Medicine Faculty Publications

Introduction In the USA, opioid analgesic use and overdoses have increased dramatically. One rapidly expanding strategy to manage chronic pain in the context of this epidemic is medical cannabis. Cannabis has analgesic effects, but it also has potential adverse effects. Further, its impact on opioid analgesic use is not well studied. Managing pain in people living with HIV is particularly challenging, given the high prevalence of opioid analgesic and cannabis use. This study's overarching goal is to understand how medical cannabis use affects opioid analgesic use, with attention to Δ9-tetrahydrocannabinol and cannabidiol content, HIV outcomes and adverse events. Methods and …

Downeast Maine Mat Expansion Project: Year 2 Data Summary, Mary Lindsey Smith Phd, Evelyn Ali Bs, Tyler Egeland Ba

Substance Use Research & Evaluation

This report summarizes the Year 2 activities of the Healthy Acadia Downeast Maine MAT Expansion Project. Through a collaborative effort of Healthy Acadia, its providers, the Downeast Substance Treatment Network and Downeast Substance Use Response Coalition, the project utilized multiple evidence-based strategies to combat opioid use disorder (OUD) in Downeast Maine.

FMI: M. Lindsey Smith, PhD, m.lindsey.smith@maine.edu

Behavioral And Enhanced Perinatal Intervention (B-Epic): A Randomized Trial Targeting Tobacco Use Among Opioid Dependent Pregnant Women, Amanda Fallin-Bennett, Michelle R. Lofwall, Teresa M. Waters, Paul Nuzzo, Janine Barnett, Letitia Ducas, Andrea Mccubbin, Niraj R. Chavan, Lisa Blair, Kristin Ashford

Nursing Faculty Publications

Background

Opioid use during pregnancy is a significant public health issue. The standard of care for treating opioid use disorder during pregnancy includes medications for opioid disorder (MOUD). However, tobacco use often goes unaddressed among pregnant women on MOUD. In 2018, our team received a National Institute on Drug Abuse (NIDA) funded R34 to conduct a three year-randomized trial to test the feasibility of a novel tobacco intervention for pregnant women receiving MOUD.

Aims

The aims of this study are: (1) to determine the impact of the B-EPIC intervention on maternal tobacco use and stage of change; (2) to determine …

Predictors Of Opioid And Alcohol Pharmacotherapy Initiation At Hospital Discharge Among Patients Seen By An Inpatient Addiction Consult Service, Honora Englander, Caroline King, Christina Nicolaidis, Devin Collins, Alisa Patten, Jessica Gregg, P. Todd Korthuis

School of Social Work Faculty Publications and Presentations

Background:

Medications for opioid use disorder (MOUD) and alcohol use disorder (MAUD) are effective and under-prescribed. Hospital-based addiction consult services can engage out-of-treatment adults in addictions care. Understanding which patients are most likely to initiate MOUD and MAUD can inform interventions and deepen understanding of hospitals’ role in addressing substance use disorders (SUD).

Objective:

Determine patient- and consult-service level characteristics associated with MOUD/MAUD initiation during hospitalization.

Methods:

We analyzed data from a study of the Improving Addiction Care Team (IMPACT), an interprofessional hospital-based addiction consult service at an academic medical center. Researchers collected patient surveys and clinical data from September …

Historical Trauma Response Scores As A Function Of Unresolved Grief And Substance Use Disorder In American Indian Populations, Andrew R. Saunders

Undergraduate Research Symposium

Abstract

Researchers are interested in the outcomes of interventions, specifically, measuring historical trauma (HT) among American Indian/Alaska Native communities and the long-term distress and substance abuse as a result of historical trauma response (HTR). Previous literature has implicated limitations in the clinical conceptualization of the relationship between intergenerational transfer of HTR and substance abuse. The aim of the current study is to examine treatment efficacy of 50 homosexual, American Indian males randomized to a culturally-adapted juxtaposition of (1) Group Interpersonal Psychotherapy (IPT), (2) Cognitive Processing Therapy (CPT), and (3) Historical Trauma and Unresolved Grief Intervention (HTUG), or (4) waitlisted on …

Rurality Of Medical Provider And Race Of Patient As Risk Factors For Overdose In Opioid Use Disorder Populations, Christopher Vance, Colleen Mulligan, David Von Nordheim, Jodi Heaps-Woodruff Ph.D.

Undergraduate Research Symposium

Title: Rurality of medical provider and race of patient as risk factors for overdose in opioid use disorder populations

Background

This study examines the outcomes of medication assisted treatment (MAT) for opioid use disorders (OUD) based on location of treatment and race of the individual seeking treatment. Opioid use in the United States has been disproportionately rising in the last decade and there is evidence of unequal treatment based on different social disparities, namely rurality and race. Discriminatory distribution of medication and treatment for individuals seeking OUD along the lines of race and rurality is an issue of grave importance …

Why Can't Homeless Addicts Get Help Too, Rachael D. Causland

English Department: Research for Change - Wicked Problems in Our World

Homeless people today struggle more with addiction than people who have stability in their life. Whether it’s due to financial issues, or not having a support system, homeless people struggle to get the help they need for both their addiction and their homelessness. A high number of homeless people report to have started an addiction since being homeless, and they do so to stay alive, in turn people are continuing to stay homeless and many of these people are dying of overdoses or just staying stuck in the situation they are forced to deal with alone. There are some states …

Substance Use Among Rural And Urban Youth And Young Adults, Jennifer D. Lenardson Mhs, Nathan Paluso Mph, Erika C. Ziller Phd

Mental Health / Substance Use Disorders

Rural youth and young adults have historically had higher use rates of alcohol and other substances than their urban counterparts. Recent research suggests that rates of youth and young adult alcohol and other substance use have declined over the past two decades, but we have limited knowledge of whether and how current rural and urban substance use patterns may differ. As national substance use rates decline, it is important to re-assess differences in use among rural versus urban youth and young adults. This study uses data from the National Survey of Drug Use and Health (NSDUH) to examine rural-urban differences …

A Markov Chain Approach For Forecasting Progression Of Opioid Addiction, Abhijit Gosavi, Susan L. Murray, N. Karagiannis

Engineering Management and Systems Engineering Faculty Research & Creative Works

The U.S. is currently facing an opioid crisis. Naltrexone is a common treatment for drug addiction; it reduces the desire to take opiates. However, addicts often stop treatment or continue to use opioids while in treatment. This results in increased fatalities and associated costs. A Markov-chain model is presented to analyze the progression of opioid addiction to assist the medical community in developing appropriate treatments. The model includes patients who continue opiate use while on naltrexone (blocked patients) and those who use opiates after missing naltrexone doses (unblocked patients). The other types of patients are abstinent (the best-case scenario) and …

The Relationship Between In-Play Betting And Gambling Problems In An Australian Context Of Prohibited Online In-Play Betting, Sally Melissa Gainsbury, Brett Abarbanel, Alex Blaszczynski

International Gaming Institute Faculty Publications

Internationally, Internet gambling is increasingly permitted under regulated licensing conditions; however, the specific products that are legal varies between jurisdictions. Online sports and race wagering are now legal in many jurisdictions, but in-play betting (also referred to as "live action" or "in-the-run" betting) is often restricted. In-play betting enables bets to be placed on an event after it has commenced. Prohibitionist policies often cite the potential for this type of betting to increase risk of gambling problems. This study aimed to identify which online bettors are most likely to engage in in-play betting, and to investigate the relationship between in-play …

E. Behavioral Evaluation And Addiction Management (Beam) Team, Deanne Niedziela

Year of the Nurse: Clinical Scholarship Presentations

No abstract provided.

Motivations For Treatment Engagement In A Residential Substance Use Disorder Treatment Program: A Qualitative Study, Patrick J. Dillon, Satish K. Kedia, Oluwaseyi O. Isehunwa, Manoj Sharma

Public Health Faculty Publications

Aims: The aim of this study was to explore perspectives on motivations for treatment engagement from substance use disorder (SUD) clients in a long-term residential rehabilitation program. Design and Methods: A convenience sample of 30 clients who were enrolled in a year-long SUD treatment program at a residential rehabilitation facility took part in in-depth interviews. Interview transcripts were analyzed using the directed content analysis approach. Results: Participant accounts indicated that their treatment engagement was motivated by factors that aligned with the six primary constructs of the Health Belief Model: (i) perceived susceptibility (eg, believing that their substance use required intervention …

Factors Associated With Binge Drinking During The Transition Into Adulthood: Exploring Associations Within Two Distinct Young Adult Age Ranges, Tamara Leech, Sarah Jacobs, Denis Watson

Department of Public Health Scholarship and Creative Works

Background:

Binge drinking among young adults aged 18-21 years has declined over the past decade, but binge drinking rates among people 22-25 years old have remained largely the same. This steady trend in later years represents a departure from the traditional course of maturing out of risky alcohol use, perhaps because young adults are delaying the transition into adulthood.

Aims:

This paper explores the relationship between binge drinking and aspects of the transition into adulthood that could inform interventions targeting these two distinct groups of young adults.

Methods:

We use survey data on 1,081 young adults aged 18-25 living in …

Harm Reduction In Prison Settings: A Relevant Approach To Reduce Hiv Transmission?, Amine Ghrabi

English Language Institute

Harm reduction defines a set of policies and interventions aiming to address the adverse health consequences associated with drug use. Compared to the general population, prisoners are disproportionally affected by HIV. Thanks to its strong emphasis on public health and human rights principles, harm reduction can effectively reduce transmission of HIV inside prison settings.

Mechanisms Study: Using Game Theory To Assess The Effects Of Social Norms And Social Networks On Adolescent Smoking In Schools—Study Protocol, Ruth F. Hunter, Felipe Montes, Jennifer M. Murray, Sharon C. Sanchez-Franco, Shannon C. Montgomery, Joaquín Jaramillo, Christopher Tate, Rajnish Kumar, Laura Dunne, Abhijit Ramalingam, Erik O. Kimbrough, Erin Krupka, Huiyu Zhou, Laurence Moore, Linda Bauld, Blanca Llorente, Olga L. Sarmiento, Frank Kee

Economics Faculty Articles and Research

This proof of concept study harnesses novel transdisciplinary insights to contrast two school-based smoking prevention interventions among adolescents in the UK and Colombia. We compare schools in these locations because smoking rates and norms are different, in order to better understand social norms based mechanisms of action related to smoking. We aim to: (1) improve the measurement of social norms for smoking behaviors in adolescents and reveal how they spread in schools; (2) to better characterize the mechanisms of action of smoking prevention interventions in schools, learning lessons for future intervention research. The A Stop Smoking in Schools Trial (ASSIST) …

A Mathematical Model Of The Opioid Epidemic In The State Of Maine, Cole Butler

Honors College

For the past two decades the United States has been embroiled in a prescription drug epidemic that has since grown in magnitude and complexity. The ripples of this epidemic have been especially apparent in the state of Maine, which has fought hard to mitigate the damage caused by addiction to pharmaceutical and illicit opioids. Us- ing data from state and federal sources, we construct a mathematical model capturing the dynamics of the opioid epidemic in the state of Maine, specifically as it pertains to pharmaceutical opioids and heroin. Parameter fitting is performed followed by an uncertainty analysis to quantify potential …

Life Experiences Associated With Change In Perpetration Of Domestic Violence., Avanti Adhia, Vivian H Lyons, Hannah Cohen-Cline, Ali Rowhani-Rahbar

Articles, Abstracts, and Reports

BACKGROUND: This study assessed whether several adult life experiences, including loss of support, loss of food security, loss of housing, and substance use cessation, are associated with change in domestic violence (DV) perpetration from early to later adulthood. Using 2015 to 2016 cross-sectional, self-report survey data from Medicaid enrollees in Oregon (N = 1620), we assessed change in DV perpetration from early adulthood (19-30 years) to later adulthood (≥ 31 years of age), cut points determined by existing survey questions. Multinomial logistic regression models were constructed to estimate the association between life experiences and physical DV perpetration using odds ratios …

Diet, Nutrition, And Substance Use Disorder, Mateja R. Savoie-Roskos, Ashley Yaugher, Alise Williams Condie, Gabriela Murza, Maren Wright Voss, Kandice Atisme

All Current Publications

Consuming a healthy diet can benefit everyone—especially individuals with substance use disorder (SUD), a disorder that occurs when frequent use of drugs or alcohol causes impairment, health issues, and difficulties with managing daily responsibilities (Substance Abuse and Mental Health Services Administration [SAMHSA], 2020). Although often overlooked, nutrition can play a key role in the treatment and recovery process for individuals with SUD, and should be included as part of a holistic approach toward recovery. In this fact sheet we will review how diet and nutrition are impacted during an active addiction, and the influence nutrition can have on treatment and …

Managing Substance Use Disorder Through A Walking/Running Training Program, Chia-Liang Dai, Ching-Chen Chen, George B. Richardson, Howard R. D. Gordon

College of Education Faculty Research

While emerging studies have demonstrated the benefit of exercise in Substance Use Disorder (SUD) recovery outcomes, lack of motivation to engage in exercise has been indicated as one of many perceived barriers that contribute to low recruitment and adherence rates in SUD treatment. The current study aimed to explore participants’ perceptions of attending a supervised exercise program (boot camp workouts, walking/running practice, and a race event) while in treatment for SUD. A total of 109 participants were recruited to a 14-week exercise training program and 61 chose to participate in, and completed, a race at the close of the program. …

Post-Traumatic Stress And Marijuana Outcomes: The Mediating Role Of Marijuana Protective Behavioral Strategies, Hallie R. Jordan, Michael B. Madson, Adrian J. Bravo, Matthew R. Pearson

Faculty Publications

Background: The present study investigated the mediating role of protective behavioral strategies for marijuana (PBSM) on the relationship between posttraumatic stress disorder (PTSD) and marijuana outcomes (i.e. marijuana use frequency, marijuana use quantity, cannabis use disorder (CUD) symptoms, and marijuana-related problems).

Methods: Participants were 1,107 traditional age college students (M_age = 20.26, SD = 3.32; 66.5% White, non-Hispanic; 68.8% female), who reported consuming marijuana at least once in the last 30 days and completed measures of PTSD symptoms, PBSM, and marijuana-related outcomes.

Results: PBSM significantly mediated the positive relationships between PTSD symptoms and both CUD symptoms and marijuana-related …

Does Early Physical Therapy Intervention Reduce Opioid Burden And Improve Functionality In The Management Of Chronic Lower Back Pain?, Shedrick Martin, Kimberly Tallian, Victoria T Nguyen, Jason Van Dyke, Harminder Sikand

Articles, Abstracts, and Reports

Introduction: Chronic lower back pain is a leading cause of disability in US adults. Opioid use continues to be controversial despite the Centers for Disease Control and Prevention guidance on chronic pain management to use nonpharmacologic and nonopioid pharmacologic interventions. The objectives of the study were to assess the impact of early physical therapy (PT) intervention on improving functionality and reducing opioid burden in patients with chronic lower back pain.

Methods: A single-center, retrospective chart review of patients receiving ≥6 PT visits and treated with either opioids first (OF) or PT first (PTF) therapy for chronic lower back pain were …

Feasibility And Acceptability Of A Culturally- And Linguistically-Adapted Smoking Cessation Text Messaging Intervention For Latino Smokers., Francisco Cartujano-Barrera, Lisa Sanderson Cox, Evelyn Arana-Chicas, Mariana Ramírez, Jaime Perales-Puchalt, Pamela Valera, Francisco J. Díaz, Delwyn Catley, Edward F. Ellerbeck, Ana Paula Cupertino

Manuscripts, Articles, Book Chapters and Other Papers

Objective: Assess the feasibility and acceptability of a culturally- and linguistically-adapted smoking cessation text messaging intervention for Latino smokers. Methods: Using a community-based strategy, 50 Latino smokers were recruited to participate in a smoking cessation pilot study. Participants received a 12-week text messaging intervention and were offered Nicotine Replacement Therapy (NRT) at no cost. We assessed biochemically verified abstinence at 12 weeks, text messaging interactivity with the program, NRT utilization, self-efficacy, therapeutic alliance, and satisfaction. Results: Participants were 44.8 years old on average (SD 9.80), and they were primarily male (66%) and had no health insurance (78%). Most of the …

Validation Of A Brief Pornography Screen Across Multiple Samples, Shane W. Kraus, Mateusz Gola, Joshua B. Grubbs, Ewelina Kowalewska, Rani A. Hoff, Michał Lew-Starowicz, Steve Martino, Steven D. Shirk, Marc N. Potenza

Psychology Faculty Research

Background and Aims To address current gaps around screening for problematic pornography use (PPU), we initially developed and tested a six-item Brief Pornography Screen (BPS) that asked about PPU in the past six months. Methods and Participants We recruited five independent samples from the U.S. and Poland to evaluate the psychometric properties of the BPS. In Study 1, we evaluated the factor structure, reliability, and elements of validity using a sample of 224 U.S. veterans. One item from the BPS was dropped in Study 1 due to low item endorsement. In Studies 2 and 3, we further investigated the five-item …

The Development Of The Compulsive Sexual Behavior Disorder Scale (Csbd-19): An Icd-11 Based Screening Measure Across Three Languages, Beáta Bőthe, Marc N. Potenza, Mark D. Griffiths, Shane W. Kraus, Verena Klein, Johannes Fuss, Zsolt Demetrovics

Psychology Faculty Research

Background Compulsive Sexual Behavior Disorder (CSBD) is included in the eleventh edition of The International Classification of Diseases (ICD-11) as an impulse-control disorder. AimsThe aim of the present work was to develop a scale (Compulsive Sexual Behavior Disorder Scale–CSBD-19) that can reliably and validly assess CSBD based on ICD-11 diagnostic guidelines. Method Four independent samples of 9,325 individuals completed self-reported measures from three countries (the United States, Hungary, and Germany). The psychometric properties of the CSBD-19 were examined in terms of factor structure, reliability, measurement invariance, and theoretically relevant correlates. A potential threshold was determined to identify individuals with an …

Stigma, Help Seeking, And Substance Use, Daniel Gutierrez, Allison Crowe, Patrick R. Mullen, Laura Pignato, Shuhui Fan

Arts & Sciences Articles

Researchers used path analysis to examine self-stigma, help seeking, and alcohol and other drug (AOD) use in a community sample of individuals (N = 406) recruited through the crowdsourcing platform MTurk. Self-stigma of help seeking contributed to AOD use and was mediated by help-seeking attitudes. We discuss the implications for advocacy and stigma reduction in substance use treatment. Counselors and counselor educators can implement and advocate for interventions and training that increase positive attitudes toward seeking help, such as providing appropriate training with supervisees and counselors-in-training, providing clients and the community with mental health literacy, and engaging in more advocacy. …

Identifying And Managing Substance Abuse In The Emergency Department, Nelsy M. Zuniga

College of Pharmacy Student Research

No abstract provided.

The Stories Behind The Struggle: A Closer Look At First Experiences With Opioid Misuse, Khary K. Rigg, Shannon M. Monnat, Katherine Mclean, Ashton Verdery, Glenn Sterner

Population Health Research Brief Series

The opioid crisis is a national public health emergency. Over 47,000 people in the U.S. died of opioid overdoses in 2017. Improving our knowledge about how people first come to misuse opioids can help to inform prevention and treatment interventions. This research brief shows that opioid misuse most often begins before age 25, most people obtain the opioids they misuse from friends and family rather than a health care provider, and experimenting and coping with life stressors are the most common motivations for starting opioid misuse.

Substance Use Prevention Services In Juvenile Justice And Behavioral Health: Results From A National Survey, Rodney Funk, Hannah K. Knudsen, Larkin S. Mcreynolds, John P. Bartkowski, Katherine S. Elkington, Ellen H. Steele, Jessica M. Sales, Christy K. Scott

Behavioral Science Faculty Publications

BACKGROUND: This study examined the national availability of substance use prevention (SUP) within juvenile justice (JJ) and their primary behavioral health (BH) providers, and the relationships between the availability of SUP and agency-level measures of organizational structure, staffing, and youth characteristics. A three-stage national probability sampling process was used to select participants for a national survey that included, among other facets of community supervision (CS) and BH practices, questions on agency characteristics, youth characteristics, whether the agency/provider directly provided SUP services, and whether the agency/provider directly provided substance use and/or mental health treatment. This paper focuses on SUP services along …

2020 County Health Rankings Tennessee Data And Updated Substance Abuse 2005-2019, Kelsey L. Grabeel, Jenny Moore

Faculty Publications

No abstract provided.

Marijuana And Depression, Pratik Sharma, Ramona Stone

Public Health Sciences Student Work

Purpose: As the country struggles to address an epidemic of alcohol and E-cigarette, a wide-ranging category of natural substance “marijuana” have provoked a new sense of public urgency over the past decade. Notwithstanding the federal ban, selling and use of non-medical marijuana continues to escalate due to state legalization process. The purpose of this cross-sectional study is to determine the relationship between marijuana use and depression.

Methods: The 2013-2014 National Health and Nutrition Examination Survey (CDC) data was used to test the association between marijuana use and depression. This nationally representative weighted sample included N=62,769 adults ages 14 years or …