Medicine and Health Sciences Commons^™

Implementing Interventions To Improve Care For Perinatal Mothers With Substance Use Exposure, Katrina Munoz, Bsn, Rn, Rnc-Mnn, Le

St. Joseph Hospital, Orange, CA. Evidence Based Practice Conference

No abstract provided.

Opioid Abuse: Are Doctors Creating The Problem?, Nguyen Tran

Symposium of Student Scholars

Opioid abuse and overdose are serious health problems in the United States. Current research has concentrated on the treatment and prevention of opioid abuse. Using data from the Controlled Substance Utilization Review and Evaluation System (CURES) for California zip codes, my research focuses on the causes of opioid overdose by considering the relationships between the following variables within each zip code: population size, average number of prescriptions per doctor, percentage of people who receive opioid prescriptions, percentage of people receiving the same prescription drug from 3 or more doctors, average number of opioid pills per prescription and number of people …

Accidental Overdoses: Insights To Aid In Prevention, Annabel Nganga

Symposium of Student Scholars

Having lost a friend six years ago to an accidental cocaine overdose, I am very passionate about spreading awareness of accidental drug overdoses that have affected thousands of families countrywide. According to past research, deaths resulting from opiates specifically have been on the rise, and a significant number of deaths in the United States for those below fifty years are caused by drug overdoses. Data exists indicating which states have more overdoses. The data set I will be using includes variables on race, sex, age, drug with which person overdosed, location of the overdose, ultimate cause of death and year …

The Dopamine D3 Receptor Antagonist Vk4-40 Attenuates Morphine-Induced Hyperactivity But Not Cocaine-Induced Hyperactivity In Mice, Desta M. Pulley, Jessica J. Debski, Daniel Manvich

Rowan-Virtua Research Day

In light of the increasing rates of opioid abuse in the US, the search for viable medications to treat opioid abuse disorder (OUD) has become ever more urgent. Opioids exert their abuse-related effects in part by indirectly increasing dopamine (DA) neurotransmission in the mesolimbic system, a dopaminergic projection arising in the ventral tegmental area and terminating in the nucleus accumbens. The DA D3 receptor (D3R), which belongs to the D2 family of dopamine receptors (D2, D3 , D4 receptor subtypes), is highly expressed in these brain regions and has shown strong potential as a pharmacotherapeutic target for the treatment of …

Acute Flecainide Toxicity Treated With Intravenous Lipid Emulsion, Joseph S. Schreiner

Rowan-Virtua Research Day

Flecainide is a Vaughn-Williams class IC antiarrhythmic used in the treatment of supraventricular tachycardias including atrial fibrillation. While overdose is rare, its negative effects on cardiac inotropy and conduction pathways can be readily fatal. This is further complicated by the redistribution of the drug out of the plasma and deposition in tissue, rendering reversal by sodium bicarbonate (the standard first line treatment agent) relatively ineffective. A case study of the successful treatment of hemodynamic collapse using sodium bicarbonate in conjunction with intravenous lipid emulsion (ILE) in a patient who ingested a large amount of flecainide in a suicide attempt will …

Neuroactivational And Behavioral Correlates Of Psychosocial Stress-Induced Cocaine Seeking In Rats, Nicole M. Hinds, Ireneusz D. Wojtas, Desta M. Pulley, Stephany J. Mcdonald, Samantha De Guzman, Nicole E. Hubbard, Colin M. Kulick-Soper, Jessica J. Debski, Bianca Patel, Daniel Manvich

Rowan-Virtua Research Day

A prominent feature of cocaine abuse is a high risk of relapse even despite prolonged periods of abstinence. Psychosocial stress is thought to be a major contributor to the onset of cocaine craving and relapse in human substance abusers, yet most preclinical models of stress-induced relapse employ physical stressors (e.g., unpredictable footshock) or pharmacological stressors (e.g., yohimbine to elicit a drug seeking response) and do not rely upon psychosocial stress per se. Importantly, social stressors are well known to activate distinct neural circuits within the brain as compared to other stressors. It is therefore possible that currently available animal models …

Opioid Lifeline Community Service Project, Ekrem Cetinkaya, Cam'ron Klotz, Harvy Patel

Rowan-Virtua Research Day

The opioid epidemic has claimed the lives of thousands of people over the last decade due to overprescribing, synthetic opioids, and lack of treatment options. Project Opioid Lifeline was created as a mission to combat this issue by equipping the Camden County, NJ population with the necessary information to advocate for themselves and others. This project aims to find and centralize available resources for residents of Camden County by including addiction treatment centers, Narcan training and distribution, and unused medication drop off locations. Over the last nine months, partnerships were formed with community leaders and organizations, such as the Neuromusculoskeletal …

Robotripping: The Dangers Of Abusing Dextromethorphan, Tiffany Sin, James Espinosa, Dana Fichter

Rowan-Virtua Research Day

Dextromethorphan (3-methoxy-N-methylmorphinan), also known as “DXM,” is a synthetically produced drug available in many over-the- counter (OTC) cough and cold medications as a centrally acting cough suppressant that binds to NMDA receptors. In a 2006 national survey of 50,000 students, 4, 5, and 7% of 8, 10, and 12th graders reported DXM abuse in the past year. In high doses, DXM can cause euphoria, hallucinations, dissociations, and distortion of cognition and perception. DXM abuse is also known as “Robotripping,” “Robodosing,” “Dexing,” “Tussin,” or “Triple Cs” because Robitussin® and Coricidin® Cough and Cold are most frequently abused. DXM has replaced codeine …

A Case Of Cocaine Toxicity From Body Stuffing, Justin Smith, James Lee, Alan Lucerna, James Espinosa

Rowan-Virtua Research Day

Body stuffing refers to the ingestion of an illegal substance in an effort to conceal it and avoid prosecution. This is distinct from, and more common than, the practice of body packing in which large amounts of an illegal substance are carefully packaged and ingested to be transported discreetly by smugglers [1]. While body packers tend to ingest much larger quantities of a drug, they are less prone to developing symptoms of drug toxicity due to the meticulous packaging methods used when compared with those who ingest packets of drugs in haste to avoid prosecution [2]. Many substances have been …

An Analysis Of Phenibut (Ss -Phenyl-Y-Aminobutyric Acid) Withdrawal, Michael Morris, James Espinosa, Robin Lahr, Alan Lucerna

Rowan-Virtua Research Day

Phenibut (ß -phenyl-y-aminobutyric acid) is a psychoactive GABA analogue marketed as a nutritional supplement and “nootropic” online. Phenibut consumption poses a high risk of potential abuse. Withdrawal from Phenibut mimics benzodiazepine and alcohol withdrawal. Without proper management, Phenibut withdrawal may be equally as dangerous as benzodiazepine and alcohol withdrawal. Baclofen can be prescribed for outpatient symptomatic relief of Phenibut withdrawal.

Barriers To Alternative Narcotic Education And Treatment In Young Adults In New Jersey, Shubh Bhambri

Rowan-Virtua Research Day

The purpose of this study is to determine alternative methods and programs that result in better outcomes for young adults dealing with opioid addiction in New Jersey while identifying potential barriers that prevent the implementation of these programs.

Opioid Use And Harm Reduction, Elise Bourassa, David Lee, Jason Rogers, Christian Silverthorne

Thinking Matters Symposium

Calls for various harm reduction approaches to the opioid epidemic are increasing in activist communities (Chapkis, 2020; Kennedy-Hendricks et al., 2019; Sederer & Marino, 2018). Given that harm reduction approaches, if implemented, will be provided by people in various helping professions, the current study investigates the relationship between choice of human service-focused college major and level of support for harm reduction interventions for people who use opioid drugs. A quantitative survey that aims to measure knowledge and perceptions of harm reduction strategies has been disseminated to students in social work, counseling, public health and nursing departments at the University of …

370— Treatment For Alcohol Addiction Among Native Americans In The United States, Jacob Reid

GREAT Day Posters

This poster aims to summarize some of the issues and policies surrounding alcohol addiction among Native Americans in the US.

Sexual Orientation, Substance Misuse, And Sexual Misconduct At A Conservative Christian University, Maci Chen

Honors Scholars & Undergraduate Research Poster Symposium Programs

College students in general tend to have high rates of substance use and abuse. Sexual minority college students show high rates of substance use and abuse. These findings are consistent across studies of sexual minority students and their relation to substances. Sexual minority populations are also more at-risk for becoming victims of sexual harassment and assault. Minority stress theory hypothesizes that LGBTQ+students at Christian universities may face heightened stigmatization or alienation, perhaps because of Christian norms/beliefs supporting heterosexual orientation.

Naloxone/Buprenorphine, Methadone, Naltrexone And Their Role In Medication Assisted Treatment, Robert Barrett

Capstone Showcase

Abstract

Opioid use disorder (OUD) is an increasingly common diagnosis that has drastically increased in the last 5 years. Though multiple treatment modalities exist for treating OUD (naltrexone, buprenorphine, methadone), few studies have compared treatment outcomes in adults on long term therapy. This is an important topic to understand as providers as we will undoubtedly come into contact with patients either actively abusing opioid antagonists or in recovery from opioid abuse. Since the introduction of Oxycontin and subsequent over prescription of opioid analgesics, opioid overdoses have increased by over twelve-fold. Once providers began to realize a widespread pattern of abuse, …

Opioid Use Disorder: The Timeline For Medication Assisted Therapy, Alexander Cristofori

Capstone Showcase

Opioid Use Disorder is patterns of opioid use leading to withdrawal, giving up important life events in order to use opioids, and excessive time spent using opioids, to name a few diagnostic criteria. The clinical progression of the disorder involves periods of acute exacerbation and remission that are cyclic in nature. Treatment is most effective when it includes both pharmacological and psychosocial modalities, referred to as medication assisted therapy (MAT). Three drugs used commonly in MAT-based treatment for OUD from oldest to newest include Methadone, Buprenorphine-naloxone, and Naltrexone. Treatment program models that prioritize total abstinence from the addictive substance attached …