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Full-Text Articles in Medicine and Health Sciences
117— The Effects Of Comorbid Alcohol And Cocaine Use On A Cognitive Maze Task, Shreyya Malik
117— The Effects Of Comorbid Alcohol And Cocaine Use On A Cognitive Maze Task, Shreyya Malik
GREAT Day Posters
In U.S., 1 out of 4 adults reported binge drinking in the past month, a prevalence that increases to over 50% in college populations. Binge drinking is a common precursor for alcohol use disorder, and risk of polydrug use also increases.Cocaine is frequently used in combination with alcohol. Little is known about the history of binge drinking and comorbid cocaine influence on memory. We developed a mouse model of alcohol and cocaine co-use to investigate how comorbidity influences performance on a working memory task. We ran two groups of mice that differed in their history of alcohol use. Group 1 …
118— Environmental Enrichment As A Treatment For Cocaine Relapse, Shreyya Malik
118— Environmental Enrichment As A Treatment For Cocaine Relapse, Shreyya Malik
GREAT Day Posters
Cocaine addiction is a problem for millions of people, however we are still lacking an effective treatment. It is characterized by compulsive behaviour which marks difficulties in remaining abstinent, with a high risk of relapse. Here, I focus on the interaction between the post-drug environment and drug-seeking by testing one potential environmental treatment, an enriched environment (EE), to reduce risk of cocaine relapse. This study proposes to investigate neural circuits involved in environmental protection of context-induced relapse. Mice exposed to cocaine will be assessed for preference of a cocaine-associated context using the conditioned place preference (CPP) paradigm. Mice will then …