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Full-Text Articles in Medicine and Health Sciences
Exercise To The Rescue: An Analysis Of Altered Metabolic Gene Regulation Post-Exercise In Lean And Obese Individuals, Brandon Mudd
Exercise To The Rescue: An Analysis Of Altered Metabolic Gene Regulation Post-Exercise In Lean And Obese Individuals, Brandon Mudd
Mahurin Honors College Capstone Experience/Thesis Projects
The skeletal muscle of obese individuals exhibits a depressed ability to metabolize fats. Exercise training is thought to rescue this dampened ability to metabolize fats; mediated by a coordinated increase in the expression of a network of genes that regulate metabolism and fuel utilization. The purpose of this study is to determine the exercise-induced regulation of metabolically important genes in lean and obese individuals. Muscle biopsies (one pre-exercise/baseline and one immediately post-exercise) were obtained from 4 lean (BF% 24.4 ± 5.5; 23.5 yrs ± 1.9) and 13 obese (BF% 39.7 ± 2.4; 26.1 yrs ± 2.3), age-matched, relatively young subjects, …
The Implications Of Different Types Of Diet And Exercise On Human Health, Bethanne C. Clayton
The Implications Of Different Types Of Diet And Exercise On Human Health, Bethanne C. Clayton
Masters Theses & Specialist Projects
There is need for enhanced prevention and treatment methods to combat sedentary lifestyle, obesity, and chronic disease by investigating the impact of specific exercise modalities and dietary factors on human health. The purposes of this study were: 1) to assess self-selected and perceived exercise intensity during High-Intensity Functional Training (HIFT) between males and females and to determine variables that predict self-selected exercise intensity (%VO2max) and/or perceived intensity (RPE) and 2) to investigate the impact of obesity on skeletal muscle metabolism in response to lipid oversupply by analyzing the responses of genes linked with fatty acid oxidation and inflammation in lean …