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Cyp1a2 Genotype And Acute Effects Of Caffeine On Resistance Exercise, Jumping, And Sprinting Performance, Jozo Grgic, Craig Pickering, David Bishop, Brad J. Schoenfeld, Pavle Mikulic, Zeljko Pedisic
Cyp1a2 Genotype And Acute Effects Of Caffeine On Resistance Exercise, Jumping, And Sprinting Performance, Jozo Grgic, Craig Pickering, David Bishop, Brad J. Schoenfeld, Pavle Mikulic, Zeljko Pedisic
Publications and Research
Background: It has been suggested that polymorphisms within CYP1A2 impact inter-individual variation in the response to caffeine. The purpose of this study was to explore the acute effects of caffeine on resistance exercise, jumping, and sprinting performance in a sample of resistance-trained men, and to examine the influence of genetic variation of CYP1A2 (rs762551) on the individual variation in responses to caffeine ingestion.
Methods: Twenty-two men were included as participants (AA homozygotes n = 13; C-allele carriers n = 9) and were tested after the ingestion of caffeine (3 mg/kg of body mass) and a placebo. Exercise performance was assessed …