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Theses/Dissertations

1998

Exercise-induced asthma

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The Efficacy Of A 'Spacer' In The Delivery Of Salbutamol For The Prevention Of Exercise-Induced Asthma, David G. Reed Jan 1998

The Efficacy Of A 'Spacer' In The Delivery Of Salbutamol For The Prevention Of Exercise-Induced Asthma, David G. Reed

Theses : Honours

Salbutamol is a Beta-2-agonist, commonly prescribed for the prevention and reversal of Exercise induced asthma (EIA). The purpose of this study was to compare the efficacy of a spacer device in the delivery of salbutamol for the prevention of EIA Thirteen confirmed asthmatic subjects (10 female and 3 male), completed 3 exercise test sessions consisting of three treatments a) Ventolin via MDI (metered dose inhaler) and placebo via spacer, b) Ventolin via spacer and placebo via MDI and c) Placebo via spacer and MDI, randomly administered utilising a single blind, cross--over design. Following treatment, subjects completed an asthmogenic physical challenge …