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Full-Text Articles in Medicine and Health Sciences

Examining Monaural And Binaural Measures Of Phase-Locking As A Function Of Age, Larissa M. Heckler May 2015

Examining Monaural And Binaural Measures Of Phase-Locking As A Function Of Age, Larissa M. Heckler

Dissertations, 2014-2019

Understanding speech in the presence of background noise is a common complaint of middle-aged and older listeners with clinically normal audiograms. There is great interest in understanding how age-related changes in auditory physiology make it harder for older adults to understand speech in difficult listening situations, compared to young listeners. It was recently reported that middle-aged and older normal-hearing listeners showed frequency-dependent, age-related declines in the behavioral and physiological detection of interaural phase differences (Grose & Mamo, 2010; Ross et al, 2007). There is also evidence of an age-related, frequency-dependent decline in the frequency-following response (FFR) (Clinard et al., 2010), …


Pre-Pulse Inhibition Assessment Of Sound Localization In Mice: Methodological, Functional, And Genetic Considerations, Megan Klingenberg May 2015

Pre-Pulse Inhibition Assessment Of Sound Localization In Mice: Methodological, Functional, And Genetic Considerations, Megan Klingenberg

Dissertations, 2014-2019

Sound localization is an important aspect of normal hearing. The Eph/ephin family of signaling proteins, studied here, is known to guide the formation of central auditory connections in early development, particularly topographic inputs from the lateral superior olive (LSO) to the inferior colliculus (IC). Processing in the LSO and its influences on the IC are known to be heavily involved in sound localization tasks. One way to study sound localization in mice is through pre-pulse inhibition (PPI). PPI is the phenomenon by which a weak prestimulus inhibits the response to a subsequent startle stimulus. In studying sound localization, the prestimulus …


Binaural Listening In Young And Middle-Aged Adults: Interaural Phase Differences And Speech-In-Noise Measures, Caitlin Cotter May 2015

Binaural Listening In Young And Middle-Aged Adults: Interaural Phase Differences And Speech-In-Noise Measures, Caitlin Cotter

Dissertations, 2014-2019

Difficulty understanding speech in the presence of noise is a common complaint of middle-aged and older adults with and without hearing loss. There is an incomplete picture of what contributes to difficulties understanding speech-in-noise in adults who have normal audiograms. As humans we listen binaurally, so declines in binaural processing may contribute to speech-in-noise difficulties. We examined the effects of age on the upper frequency limit of interaural phase difference (IPD) detection and IPD detection at fixed frequencies. We also examined a speech-in-noise measure of spatial separation across young and middle-aged, normal-hearing individuals.

Participants were young (n=12) and middle-aged (n=8) …


Effects Of Training And Lung Volume Levels On Voice Onset Control And Cortical Activation In Singers, Nicholas A. Barone May 2015

Effects Of Training And Lung Volume Levels On Voice Onset Control And Cortical Activation In Singers, Nicholas A. Barone

Dissertations, 2014-2019

Singers need to counteract respiratory elastic recoil at high and low lung volume levels (LVLs) to maintain consistent airflow and pressure while singing. Professionally trained singers modify their vocal and respiratory systems creating a physiologically stable and perceptually pleasing voice quality at varying LVLs. In manuscript 1, we compared non-singers and singers on the initiation of a voiceless plosive followed by a vowel at low (30% vital capacity, VC), intermediate (50%VC), and high (80%VC) LVLs. In manuscript 2, we examined how vocal students (singers in manuscript 1) learn to control their voice onset at varying LVLs before and after a …