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Analgesia Followed By Long-Term Hyperalgesia Generated By Disinhibition Of The Basolateral Amygdala, Derek Atchley
Analgesia Followed By Long-Term Hyperalgesia Generated By Disinhibition Of The Basolateral Amygdala, Derek Atchley
Wayne State University Theses
Stress produces bimodal effects on pain peception. During exposure to a stressor pain responses are inibited (i.e. stress-induced analgesia). However, following long-term exposure to a stressor increases in responsiveness to painful stimuli may develop (i.e. stress-induced hyperalgesia). Here I evaluated how a key component of the subcortical defense circuit and target of stress hormones contributes to the development of both stress-induced analgesia and hyperalgesia. Bicuculline methiodide, a GABAA antagonist, injected into the basolateral amygdala was used to mimic the neural effects of a stressor or threat exposure. Immediately following injection pain responsiveness was decreased as measured by vocalizations after discharge …
The Relationship Between Generalized Anxiety Disorder In Women And Hormonal Imbalances, Self-Efficacy And Lifestyle: Implications For Licensed Professional Counselors And Counselor Educators, Gillian Bernadette Robbins
The Relationship Between Generalized Anxiety Disorder In Women And Hormonal Imbalances, Self-Efficacy And Lifestyle: Implications For Licensed Professional Counselors And Counselor Educators, Gillian Bernadette Robbins
Wayne State University Dissertations
The intent of the study was to conduct a preliminary enquiry of the relationship between Generalized Anxiety Disorder (GAD) in women and hormonal imbalances, self-efficacy, and lifestyle. Key consideration was given to the study as it points to implications for licensed professional counselors and counselor educators. A nonexperimental, correlation design was used in the study and conducted in a large urban city in Ontario, Canada. Participants in the study were female clients receiving bio-identical hormone replacement therapy (BHRT) for a minimum of three month at a Medical Health Spa. A total of 55 participants completed a demographical survey, the Generalized …