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Full-Text Articles in Medicine and Health Sciences
The Creation Of Transgenic Animal “Models” For Human Genetic Disease, Bernard Rollin
The Creation Of Transgenic Animal “Models” For Human Genetic Disease, Bernard Rollin
Biomedicine and Animal Models in Research Collection
Transgenic animals will be created to study human genetic disease as soon as the technological capability exists to do so. Extant laws permit such animals to be created. The mindset of the research community makes it inevitable. It is also clear that such diseases can cause enormous amounts of pain and suffering. Responsible researchers need to explore all possible avenues for controlling such pain and suffering. Thus far the research community has not engaged this issue vis a vis animals. The development of methodologies for controlling pain and suffering is likely to be exportable to numerous areas of animal research, …
The Ethical Judgment Of Animal Research, Shelley L. Galvin, Harold A. Herzog
The Ethical Judgment Of Animal Research, Shelley L. Galvin, Harold A. Herzog
Experimentation Collection
One hundred sixty subjects acted as members of a hypothetical Institutional Animal Care and Use Committee and evaluated five proposals in which animals were to be used for research or educational purposes. They were asked to approve or reject the proposals and to indicate what factors were important in reaching their ethical decisions. Gender and differences in personal moral philosophy were related to approval decisions. The reasons given for the decisions fell into three main categories: metacognitive statements, factors related to the animal, and factors related to the design of the experiment.