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Living With Fragile X Syndrome: Occupations As An Outcome Measure In A Clinical Trial, Theresa Chase, Ty Duong, Ana Baldinger, Kaylee Gothelf

Dissertations, Masters Theses, Capstones, and Culminating Projects

The purpose of this study was to evaluate the use of semi-structured interviews as an outcome measure in a clinical trial for children with fragile X syndrome (FXS). A qualitative approach was used to analyze twenty-five parent interviews with children with FXS who participated in a double-blind medication trial. Each participant received either sertraline or a placebo. The aim of this research was to assess differences in occupational functioning in the sertraline group and placebo group, that may not have been detected with the use quantitative outcome measures alone. Results showed greater improvements in the sertraline group in areas of …