Medicine and Health Sciences Commons^™

Identification Of Leishmania Spp. And Trypanosoma Cruzi In Sylvatic Animals In El Paso County, Texas, Mariel Christina Matamoros

Open Access Theses & Dissertations

Background Leishmaniasis and Chagas's Disease are two of the seventeen diseases considered as Neglected Tropical Diseases (NTF) by the CDC. Ten million people worldwide are at risk of being infected by Leishmaniasis and Chagas' disease affects six million people in the world; however, these are mostly cases in Latin America. The vector for Chagas' disease, triatomine, has been identified near El Paso, Texas region to be positive for Trypanosoma cruzi. Recent studies have also shown positive results for Chagas' disease and Leishmaniasis in sylvatic animals in El Paso.

Objective To determine the prevalence of Trypanosoma cruzi and/or Leishmania spp. infection …

Detecting Enzootic Leishmaniasis And American Trypanosomiasis In Stray Dogs In El Paso County, Texas And The Potential For Autochthonous Transmission To Humans, Evan James Kipp

Open Access Theses & Dissertations

Cutaneous leishmaniasis and Chagas disease (American trypanosomiasis) are two vector-borne, protozoal zoonoses whose emergence into the southern United States is a public health problem of increasing significance. Cutaneous leishmaniasis is caused by several species of intracellular protozoa in the genus Leishmania and is most often characterized by the formation of large, ulcerative skin lesions that can result in considerable scarring and permanent disfigurement. Infection with Leishmania is prevalent throughout the world in tropical and sub-tropical regions and in areas where people are regularly exposed to the hematophagous sand fly vectors that transmit the disease. Chronic infection with Trypanosoma cruzi, the …

Development Of A Novel Metallo-Lipid Microparticle Delivery System For A Leishmania Mexicana Dna Vaccine Candidate, Joanna B. Valencia

Open Access Theses & Dissertations

ABSTRACT

Background and Significance.

The leishmaniases are an important group of neglected tropical parasitic diseases caused by parasitic protozoa of the genus Leishmania. International health authorities estimate that 350 million people around the world are at risk for contracting leishmaniasis. Two million new cases occur each year and 12 million people are presently infected worldwide. Leishmaniasis is endemic throughout the Americas region including all of Central America, most of South America, Mexico and southern Texas. Leishmania is also considered a threat to the military readiness of U.S. troops deployed to the Middle East or Latin America.

First- and second-line treatments …