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Full-Text Articles in Medicine and Health Sciences
Controlling Influenza A (H1n1) In China: Bayesian Or Frequentist Approach, Dejian Lai, Chiehwen Ed Hsu
Controlling Influenza A (H1n1) In China: Bayesian Or Frequentist Approach, Dejian Lai, Chiehwen Ed Hsu
Chiehwen Ed Hsu
In this article we discuss two approaches to controlling the newly identified influenza A (H1N1) via Bayesian and frequentist statistical reasoning. We reviewed the measures implemented in China as an example to illustrate these two approaches. Since May 2009, China has deployed strict controlling mechanisms based on the strong prior Bayesian assumption that the origin of influenza A (H1N1) was from outside China and as such strict border control would keep the virus from entering China. After more than two months of hard work by Chinese health professionals and officials, the number of confirmed influenza A (H1N1) has increased steadily …
Ethical Considerations Of Genetic Presymptomatic Testing For Huntington's Disease, Alberto Coustasse, Alicia Pekar, Andrew Sikula Sr., Sue Lurie
Ethical Considerations Of Genetic Presymptomatic Testing For Huntington's Disease, Alberto Coustasse, Alicia Pekar, Andrew Sikula Sr., Sue Lurie
Management Faculty Research
The aim of this literature review was to determine if there is adequate ethical justification for presymptomatic genetic testing on potential Huntington's disease patients. Huntington's disease is a neurological genetic disorder characterized by midlife onset which consists of cognitive, physical, and emotional deterioration. Although genetic testing has traditionally been guided by the principle of autonomy, severe psychological consequences such as depression, anxiety, survival guilt, and suicide have complicated the ethical issue of providing a presymptomatic yet definitive diagnosis for an incurable disease. An analysis of available articles yielded inconclusive findings, namely due to insufficient evidence, self-selection bias of test participants, …