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Full-Text Articles in Medicine and Health Sciences
Examination Of Novel Statistical Designs For Phase Ii And Phase Iii Clinical Trials, Ayanbola Olajumoke Ayanlowo
Examination Of Novel Statistical Designs For Phase Ii And Phase Iii Clinical Trials, Ayanbola Olajumoke Ayanlowo
All ETDs from UAB
Clinical trials to determine the usefulness of a new treatment are usually conducted in four (4) phases. Each phase is designed to answer a distinct research question about the usefulness of the new treatment. Phase I trials determine the safe dose range of the new treatment identify the possible side effects and other treatment associated toxicity issues, in a small group of healthy people. In phase II trials, the efficacy and safety of the new treatment is investigated in a larger group of individuals usually from the diseased population of interest. Phase III trials, conducted in large groups of people, …
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
All ETDs from UAB
Persistent infection with certain “high-risk” types of human papillomavirus (HPV) infection is central to the development of cervical cancer. Human immunodeficiency virus (HIV)-infected women are at a higher risk of HPV infection, high grade cervical intraepithelial lesions, and cervical cancer. This study examined type-specific distribution of prevalent and incident HPV infections, clearance rates, and associated factors using novel molecular assays for HPV detection and genotyping in a cohort of 280 HIVinfected women in Alabama. First, we described the cohort’s sociodemographic characteristics and behavioral risk profile for HIV and other sexually transmitted infections, and assessed the factors associated with HIV-1 viral …
Titania Coated Hollow Glass Microspheres For Environmental Applications, Mark C. Koopman
Titania Coated Hollow Glass Microspheres For Environmental Applications, Mark C. Koopman
All ETDs from UAB
The potential applicability of titania coated hollow glass microspheres (HGMs) to the photocatalytic degradation of microbiological and organic chemical water pollutants could have dramatic positive effects on improving the quality of industrial wastewaters that empty into rivers and streams, as well as potential use in economically improving the quality of drinking water. Heterogeneous photocatalysis using titania has been extensively studied since the 1990’s because of its non-toxic nature, its high quantum yield of electrons and photo-holes, and its ability to use ambient solar radiation as a power source. Although titania embodies extraordinarily attractive properties for a range of environmental applications, …