Medicine and Health Sciences Commons^™

Public Health Research Day 2020, George Washington University

GW Research Days 2016 - 2020

No abstract provided.

Intersex Wildlife As Sentinels For Human Health And Endocrine Disruption Near Superfund Sites: A Systematic Review, Olivia Anderson, Melissa Perry

GW Research Days 2016 - 2020

Fish and wildlife are often used as sentinels for human health. This systematic review examines one aspect of wildlife health, intersex (both ovarian and testicular tissue) animals and their prevalence or severity near Superfund sites (EPA designated toxic waste sites). The body of evidence demonstrates some evidence of this indicator and more research is needed, specifically a meta-analysis that is outside the scope of this study.

Florida Red Tide Exposure: Analyzing The Respiratory Effects Experienced By The Gulf Coast Population, Katrina Zdanowicz, Cindy Liu

GW Research Days 2016 - 2020

Background: Florida red tide occurs in the Gulf of Mexico annually and has been linked to complaints of negative respiratory symptoms. Little is known about the exact association and long term effects of the exposure. Objectives: We applied the Navigation Guide to conduct a systematic review of the existing body of literature on Florida red tide exposure and respiratory effects. Methods: We applied inclusion criteria to studies found through searches of 5 scientific databases. Included studies were analyzed for risk of bias and overall strength and quality of evidence. Included studies provided self-reported symptoms and quantitative measurements of pulmonary function …

(Video) Latino Immigration And Chronic Disease: A Critical Analysis Of Socioeconomic And Psychological Mediators, Frances Anne Fernando

GW Research Days 2016 - 2020

A critical analysis of chronic disease among Latino immigrants demonstrates the interplay between the individual, socioeconomic, and pathophysiological mediators of disease. To identify the major factors involved, a conceptual framework was developed to explain the relationship between Latino immigration to the US and the manifestation of diabetes and cardiovascular disease. Mediating factors include: self-efficacy, stress, social support, access to healthcare, pathophysiological risk factors and the familial and cultural environment. As the Latino population is the fastest growing and largest minority group in America, increased support among the identified factors will target interventions with broad health and economic implications for the …

The Effects Of Spiritual Experience And Church Commitment On Mental Health And Work Performance Among A Sample Of South Korean Immigrants In The United States: A Mixed Methods Study, Chulwoo Park, Mark Edberg

GW Research Days 2016 - 2020

This sequential mixed methods study measured the effects of spiritual experience and church commitment on mental health and work performance among a sample of South Korean immigrants in the United States. It included the screening survey for assessing level of religious belief and involvement in church activities (quantitative) followed by in-depth qualitative interviews about the relationship between church attachment and mental health as well as work/school performance (qualitative), in order to obtain preliminary findings and generate insights regarding future research. High-active believers who engage in church activities were assigned as Group 1, and inactive/low-active members who still have high-level belief …

Effects Of Alcohol Consumption On Nephropathy, Retinopathy, And Neuropathy In Type 1 Diabetes In The Diabetes Control And Complications Trial (Dcct), Victoria Trapani

GW Research Days 2016 - 2020

Effects of long-term alcohol consumption have not been well studied in populations with diabetes, though regular alcohol consumption is common among American adults and it is estimated that at least 10% of Americans have diabetes. Individuals living with diabetes who are heavy alcohol consumers may be at heightened risk for diabetic complications. Using the well-phenotyped Diabetes Control and Complications Trial (DCCT) cohort of 1,246 adult subjects with type 1 diabetes, a secondary analysis was conducted to determine if relationships exist between alcohol consumption and nephropathy, retinopathy, and neuropathy at baseline, follow-up year 5, and DCCT closeout. This secondary analysis found …

Measuring The Effects Of Thc On Human Sperm Parameters Using Biomonitoring Analysis, Roxana Amaya-Fuentes, Heather Young, Courtney Irwin, Jonathan Crites, David Moody, Melissa Perry

GW Research Days 2016 - 2020

Marijuana is one of the most common substances used in the United States with more men utilizing marijuana compared to women. The effects of marijuana on the brain are well known, however, there is limited research on its effects on human sperm parameters. We examined the association between THC and human sperm parameters in participants in the Washington D.C. area. Our preliminary results suggested that THC was associated with low sperm morphology.

Background: Marijuana has a long history of human usage for medicinal, ceremonial, and religious purposes. As of January 2018, nine states including Washington D.C. have legalized it for …

Isoprene Emission Rates From Extreme Heat Exposure Due To Climatic Changes On Quercus And Populus Tree Genera: A Systematic Review, Isabella Kaser, Susan Anenberg

GW Research Days 2016 - 2020

This systematic literature review explores whether isoprene emission rates from common tree species would be exacerbated in a warming world. When isoprene reacts with other pollutants, such as nitrogen oxides, tropospheric ozone is formed. Ozone is harmful to human health and is shown to decrease lung function among many other negative respiratory effects. If the rates of emissions continue at their current levels, there may be increased rates of asthma-related ED visits and respiratory diseases among the general population.

Fasting Insulin, Glucose, And Hba1c Among Young Adults With Overweight And Obesity, Benjamin Shambon

GW Research Days 2016 - 2020

We compared fasting blood glucose, insulin, and hemoglobin A1c using baseline data collected from 460 young adults ages 18-35 enrolled in an ongoing randomized controlled clinical weight-loss trial. The goal was to determine differences within the subject pool for insulin insensitivity and pre-diabetes based on demographics. We further modeled both pancreatic beta cell function and insulin sensitivity using the homeostatic model assessment for insulin resistance (HOMA-IR).

A Triple Threat: Alcohol Use Disorders In The Presence Of Comorbid Chronic Pain Conditions And Depressive Disorders In The Collaborative Psychiatric Epidemiology Surveys, 2001-2003, Chelsea Boyd, Sean Cleary, Scott Quinlan, Debra Bernat

GW Research Days 2016 - 2020

Background: Frequently patients with chronic pain conditions have comorbid depressive disorders. The relationship between the diagnoses is often bidirectional, with the effects of one condition exacerbating the effects of the other. Alcohol use disorders (AUD) are also independently associated with both conditions. This study aims to determine the prevalence of alcohol use disorders among patients with comorbid chronic pain conditions and depressive disorders in a nationally representative sample of US adults and ascertain the characteristics of patients with all three diagnoses.

Methods: This cross-sectional analysis utilizes data from the Collaborative Psychiatric Epidemiology Surveys (CPES), 2001-2003. The sample includes respondents who …

Use Of The Adult Myopathy Assessment Tool As A Predictor Of Functional Abilities In People With Multiple Sclerosis, Kimberly Benson, Michael O. Harris-Love, Bryant A. Seamon, Mitchel T. Wallin, Heidi Maloni, Brian Hoover, Marc R. Blackman

GW Research Days 2016 - 2020

Background: People with multiple sclerosis (PwMS) are at greater risk for decreased muscle performance which may lead to decreased functional abilities. The Kurtzke Expanded Disability Status Scale (EDSS) is commonly used as a disability status rating scale in PwMS. Nevertheless, the EDSS is largely comprised of neurological tests and may not best reflect functional performance. A functional battery such as The Adult Myopathy Assessment Tool (AMAT) may better reflect functional performance. The AMAT was designed to assess both functional strength and endurance in clinical settings. However, the AMAT has not been validated for the assessment of PwMS.

Objective: The purpose …

Cognitive And Behavioral Effects Of Nitrogen Dioxide Exposure In Primary School Children: A Systematic Review, Dara L. Brown, Matias Attene Ramos

GW Research Days 2016 - 2020

A systematic literature review was conducted to identify relevant studies evaluating the relationship between nitrogen dioxide emissions and cognitive and behavioral health in children. Eight studies were identified, reviewed, and analyzed according to specific inclusion criteria. The results of the review show that there is strong evidence for an inverse relationship between nitrogen dioxide exposure and cognitive and behavioral health in primary school children. However, further research is needed to confirm the observed associations between nitrogen dioxide exposure and cognitive and behavioral health.

Acute Particulate Matter Exposure And Suicide In North East Asia: A Literature Review, Shannon Haines, Lance Price, Amanda Northcross

GW Research Days 2016 - 2020

A systematic literature review was conducted on research exploring the relationship between acute exposures to ambient particulate matter and changes in suicide rates in North East Asian countries. From the eight studies analyzed limited evidence was found and additional research about the association is suggested.

Occupational Risk Of Migrant Farm Workers In North Carolina: A Systematic Review, Ellie Ginsberg, David Michaels

GW Research Days 2016 - 2020

Latnix Migrant Farmworkers in North Carolina face a variety of occupational hazards while working in the fields. These hazards include exposure to the natural elements, pesticides, and tobacco. Sub standard housing conditions and lack of comprehensive workers compensation coupled with these hazards create an extremely dangerous working environment for these farmworkers.

"As Parents, How On Earth Are We Going To Handle This Issue": Provider And Parent Views On Sexuality-Related Challenges During Adolescence Among International Hiv-Infected Adoptees In The U.S., Sarah Alger, Cynthia Fair

GW Research Days 2016 - 2020

As the number of internationally adopted children with HIV has increased since 2010 in the U.S., more children may have additional educational needs, particularly related to sexuality, as they mature. After conducting 48 hour-long, semi-structured interviews with parents and providers, the qualitative analysis shows that many parents' adoption decisions are driven by faith, which can influence the child's ability to gain vital sexual education given their HIV status. Parents of internationally adopted children with HIV could benefit from the support of healthcare providers to better understand the importance of sexual and reproductive health during adolescence.

Interaction Between Intellectual Disability And Cerebral Palsy On The Co-Occurrence Of Autism Spectrum Disorder And Epilepsy, Prarthana Hareesh, Sean D. Cleary

GW Research Days 2016 - 2020

Intellectual disability (ID) is possibly a reason for the higher co-occurrence of Autism Spectrum Disorder (ASD) in children with epilepsy. Cerebral Palsy (CP) has also been found to co-occur with ASD (6.9%-hypotonic, 18.4%-spastic subtype) and with epilepsy (41%), but it is unclear if the co-occurrence of ASD and epilepsy varies by the presence of both, ID and CP. The purpose of this study to evaluate effect modification of CP and ID on ASD-epilepsy co-occurrence.

Does Food Insecurity Predict Obesity And Educational Achievement: A Systematic Literature Review, Emily Youner, Ami Zota

GW Research Days 2016 - 2020

The objective of this study was to determine whether food availability predicts health outcomes among children in the U.S., such as obesity rates and academic performance. Though there was some inconsistency in the findings, based on the Navigation Guide methodology, we concluded that there is inadequate evidence of correlation between food insecurity and obesity rates, yet limited evidence of correlation between food insecurity and educational achievement. Given these findings, further research is warranted to inform policy action to mitigate the effects food insecurity.

Perceived And Experienced Mental Health Needs Among Puerto Rican Community Responders In The Aftermath Of Natural Disasters, Gabriela Madrid, Amalis Cordova, Carlos Rodriquez-Diaz

GW Research Days 2016 - 2020

For the project, I will conduct a secondary data analysis using qualitative interviews that he conducted in the first semester of 2018. I will use the data he collected to describe the perceived mental health of the community responders both on the Island and in the United States. I will also provide recommendations, informed from a literature review, to address the population's needs.

Piloting Carestart™ Rapid Diagnostic Test (Rdt) To Promote Glucose-6-Phosphate Dehydrogenase (G6pd) Screening In Malaria Endemic Community In Cambodia, Bertha Nyagaya-Wojnarski, +Several Additional Authors

GW Research Days 2016 - 2020

Background: Primaquine (PQ) is the only FDA-approved drug for radical cure of Plasmodium vivax (P.v) malaria, but treatment can result in life-threatening hemolysis if given to a glucose-6-phosphate dehydrogenase deficient (G6PDd) patient. Therefore, the G6PD status of the patient with P.v must be known prior to prescribing PQ. However, a patient’s G6PD status in rural malaria endemic settings is generally unknown, illuminating the need for reliable point of care G6PD diagnostic tests as a prerequisite to safely administer PQ. To increase community PQ access in Cambodia, performance of CareStart™ G6PD rapid diagnostic tests (RDTs) needs to …

Occupational Exposure To Solvents And Associated Neurotoxicity In Construction Painters: A Systematic Review, Allison Cailliau

GW Research Days 2016 - 2020

Background

Existing evidence suggests that occupational exposure to solvents can have devastating and adverse effects on cognitive function. Individuals in the construction industry, specifically construction painters, often come in contact with these harmful chemicals on a regular basis. A solvent is a liquid that can dissolve, suspend, or extract other materials without chemical change to the solvent itself. They are present in a wide range of industries and can be used for extraction of fats and oils, degreasing, or manufacturing of paints and plastics. Their main routes of exposure are through inhalation and skin absorption, and they have a tendency …

An Assessment Of Cultural Perceptions And Recognition Of Ebola Virus Disease, And Its Correlation With Traditional Burial Practice In Rural Guinea, Chulwoo Park, Amira Roess, Sally Lahm, Mamadou Kally Bah, Mohamed Campel Camara, John Sandberg

GW Research Days 2016 - 2020

Background:

In the midst of the unprecedented Ebola outbreak in West Africa during 2014-2016, the humanitarian response to control the disease was hampered in part because there was a limited understanding of local traditional rituals or indigenous medicine (ethnomedicine) on the part of the responders. The Ebola outbreak claimed 11,310 lives, more than all other outbreaks combined. West African burial funeral ceremonies and surrounding rituals may have hindered interventions that included the forceful removal of the sick or dead from the community.

Objective:

Our objective was to understand transmission associated with traditional burial practices in rural Guinea. Through the lens …

Etiology And Management Of Hospitalized And Outpatient Diarrhea Among Children Less Than 5 Years Of Age In Lambaréné, Gabon, Christina Pugliese, Natalie Byrne, Frederique Nguema, Kafui Vodounou, Mirabeau Mbong Ngwese, Gedeon Manouana, Jean Edoa, Bayode Adegbite, Jeannot Zinsou, Ayola Adegnika, Martin Grobusch, David Diemert

GW Research Days 2016 - 2020

Objectives: Diarrhea remains a significant cause of global under-5 mortality, particularly in SubSaharan Africa (SSA). To reduce morbidity and mortality, the World Health Organization (WHO) recommends oral rehydration salts (ORS), zinc supplementation, and continued feeding or breastfeeding for all children with diarrhea to prevent dehydration and malnutrition; antibiotics only for bloody diarrhea (i.e. probable shigellosis), suspected cholera, or severe non-intestinal infections (e.g. pneumonia or sepsis); and avoidance of antidiarrheals and antiemetics owing to lack of benefit and potential for harm in young children. Gabon is an upper-middle income country in SSA for which there is a lack of recent, high …

Shigellosis And Giardiasis Among People Living With Hiv In Washington, Dc, 2012-2016, Kimesha Linton, Kerri Dorsey, Sasha Mcgee, Preetha Iyengar, Garret Lum, Rupali Doshi

GW Research Days 2016 - 2020

Background: Shigellosis and giardiasis are transmitted via food, water, and fecal-oral contact. CDC has recently reported increased shigellosis among men who have sex with men (MSM) and among people living with HIV (PLWH), particularly stage 3. Our goal was to characterize the incidence and risk factors associated with shigellosis and giardiasis among PLWH in Washington, DC, in an era of robust availability of antiretroviral treatment.

Methods: We conducted a retrospective analysis of HIV, shigellosis and giardiasis cases reported to the District of Columbia Department of Health from 2012 to 2016. We used LinkPlus to probabilistically match individuals with reported …

Breastfeeding As A Predictor Of Serum Concentrations Of Per- And Polyfluorinated Alkyl Substances In Reproductive-Aged Women And Children: A Rapid Systematic Review, Brianna N. Vannoy, Juleen Lam, Ami R. Zota

GW Research Days 2016 - 2020

Purpose of Review: Per- and polyfluorinated alkyl substances (PFASs) are synthetic chemicals widely detected in human serum, and at low levels in breast milk. We conducted a rapid systematic review on breastfeeding practices and serum concentrations of PFASs – specifically PFOS and PFOA - among reproductive-aged women and young children using the Navigation Guide systematic review methodology.

Recent Findings: We included 14 studies examining associations between breastfeeding and PFASs in infants/toddlers or pregnant/postnatal women. Breastfeeding was significantly associated with lower PFASs exposure among women and higher PFASs exposure among children. Summary: We concluded there was “sufficient” evidence supporting an association …

How Climate Effects The Tick Vector Of Lyme Disease: A Critical And Systematic Review Of The Literature, Anita Desikan, Matias Attene Ramos

GW Research Days 2016 - 2020

Background

Lyme disease (LD) is a common vector-borne disease in North America. Understanding the causes behind inter-annual fluctuations of LD incidence can help warn healthcare providers of upcoming outbreaks.

Objective

Identifying what specific climate variables affects the vector, Ixodes scapularis ticks, and ultimately LD incidence.

Methods

A systematic review was carried out to understand how climate variables affect the tick population variables that are related to LD.

Results

Twenty-one studies met the inclusion criteria. Risk of bias was generally rated “low” or “probably low” and quality of evidence was rated “moderate”. Strength of evidence was assessed for tick abundance, a …

(Video) Dirty Cotton: Occupational Pesticide Exposure And Elevated Suicide Risk Among Male Cotton Farmers In India, Bethany Natalia Kondavaty

GW Research Days 2016 - 2020

Purpose: The aim of this critical analysis was to examine the association (or lack thereof) of occupational pesticide exposure and elevated suicide risk among male cotton farmers in India.

Methods: A literature review was performed using Scopus, PubMed, and Google Scholar databases. The review included documents published before and after year 2002. Children were excluded from the search as well as women, with exception to research on gender differences in suicide.

Results: Studies outside India show a positive correlation between work-related pesticide exposure and suicide. Animal studies have shown that pesticides, as organophosphates, are toxic, …

Impact Of Water, Sanitation, And Hygiene Interventions On Environmental Enteric Dysfunction In Children In Developing Countries: A Systematic Literature Review, Abdoulaye Bangoura, Susan Anenberg

GW Research Days 2016 - 2020

Environmental Enteric Dysfunction (EED) is a global disturbance of intestinal structure and function that has its origin in environmental factors (Owino et al. 2016). As a response to prolonged and persistent inflammation, the intestine morphology is altered. EED is an important contributor to poor child cognitive development, child stunting, poor oral vaccine response, acute infections, and childhood mortality globally (Trehan et al. 2016) in developing countries.

We hypothesized that WASH interventions could reduce the risk of EED, thereby positively impacting children’s overall health. The Navigation Guide review methodology and the Grading of Recommendations Assessment and Evaluation (GRADE) were followed to …

Occupational Exposure To Organophosphate Pesticides And Its Effects On Human Sperm Parameters: A Systematic Review, Roxana E. Amaya-Fuentes, Melissa J. Perry

GW Research Days 2016 - 2020

Background

Previous research has indicated there is a decrease in sperm quality in the last 40 years. There have been a few reports that have associated occupational exposure to Organophosphate pesticides with a decrease in sperm count, abnormalities in the head or tail, and motility leading to infertility over time. Organophosphates are the most common pesticides used in the United States and have been classified as toxic to bees, wildlife, and humans by the EPA even at low exposures. Furthermore, Organophosphates are considered endocrine disrupting chemicals altering the normal function of the endocrine system. This occurs by interfering with the …

Designing A Social Norms-Based Intervention To Reduce Anemia In India: A Formative Research Protocol, Aika Aluc, Erica Sedlander, Rajiv N. Rimal, Sameera A. Talegawkar, Hagere Yilma, Wolfgang Munar

GW Research Days 2016 - 2020

Background: Economic and gender inequalities are important determinants of anemia in low and middle income countries. Gender dimensions of food security contribute to the undernutrition among women. More than half of women of reproductive age in India are anemic. Anemia causes increased risk of preterm delivery, higher maternal mortality and contributes to fatigue, which influences women’s work productivity. The World Health Organization (WHO) recommends daily oral iron and folic acid (IFA) supplements during pregnancy and weekly supplements for women of reproductive age. Despite the efforts of government programs and global donors to reduce anemia in India, both initial uptake and …

Does Occupational Exposure To Swine Increase The Risk Of Influenza? A Systematic Literature Review, Courtney Youngbar, Lance Price

GW Research Days 2016 - 2020

Background Workers who have an occupational exposure to swine may have an increased risk of influenza infection.

Objective We conducted a systematic review regarding occupational exposure to swine and influenza infection in humans.

Methods We searched articles published within the past ten years at the time of writing, and included original studies that quantified exposures to swine and resulting influenza infections in swine farm workers, including veterinarians. We evaluated the risk of bias of individual studies and the overall quality and strength of the evidence according to the Navigation Guide systematic review methodology. Twelve studies met the inclusion criteria. We …