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Full-Text Articles in Medicine and Health Sciences
What Are The Basic Self-Monitoring Components For Cardiovascular Risk Management?, Alison M. Ward, Carl Heneghan, Rafael Perera, Dan Lasserson, David Nunan, David Mant, Paul P. Glasziou
What Are The Basic Self-Monitoring Components For Cardiovascular Risk Management?, Alison M. Ward, Carl Heneghan, Rafael Perera, Dan Lasserson, David Nunan, David Mant, Paul P. Glasziou
Paul Glasziou
Background: Self-monitoring is increasingly recommended as a method of managing cardiovascular disease. However, the design, implementation and reproducibility of the self-monitoring interventions appear to vary considerably. We examined the interventions included in systematic reviews of self-monitoring for four clinical problems that increase cardiovascular disease risk.
Methods: We searched Medline and Cochrane databases for systematic reviews of self-monitoring for: heart failure, oral anticoagulation therapy, hypertension and type 2 diabetes. We extracted data using a pre-specified template for the identifiable components of the interventions for each disease. Data was also extracted on the theoretical basis of the education provided, the rationale given …
Corticosteroids For Pain Relief In Sore Throat: Systematic Review And Meta-Analysis, Gail Hayward, Matthew J. Thompson, Carl J. Heneghan, Rafael Perera, Paul P. Glasziou, Chris B. Del Mar
Corticosteroids For Pain Relief In Sore Throat: Systematic Review And Meta-Analysis, Gail Hayward, Matthew J. Thompson, Carl J. Heneghan, Rafael Perera, Paul P. Glasziou, Chris B. Del Mar
Paul Glasziou
Objective: To evaluate whether systemic corticosteroids improve symptoms of sore throat in adults and children. Design: Systematic review and meta-analysis. Data sources: Cochrane Central, Medline, Embase, Database of Reviews of Effectiveness (DARE), NHS Health Economics Database, and bibliographies. Outcome measures: Percentage of patients with complete resolution at 24 and 48 hours, mean time to onset of pain relief, mean time to complete resolution of symptoms, days missed from work or school, recurrence, and adverse events. Results: We included eight trials, consisting of 743 patients in total (369 children, 374 adults). 348 (47%) had exudative sore throat, and 330 (44%) were …
Event Rates, Hospital Utilization, And Costs Associated With Major Complications Of Diabetes: A Multicountry Comparative Analysis, Philip M. Clarke, Paul Glasziou, Anushka Patel, John Chalmers, Mark Woodward, Stephen B. Harrap, Joshua A. Salomon
Event Rates, Hospital Utilization, And Costs Associated With Major Complications Of Diabetes: A Multicountry Comparative Analysis, Philip M. Clarke, Paul Glasziou, Anushka Patel, John Chalmers, Mark Woodward, Stephen B. Harrap, Joshua A. Salomon
Paul Glasziou
Background: Diabetes imposes a substantial burden globally in terms of premature mortality, morbidity, and health care costs. Estimates of economic outcomes associated with diabetes are essential inputs to policy analyses aimed at prevention and treatment of diabetes. Our objective was to estimate and compare event rates, hospital utilization, and costs associated with major diabetes-related complications in high-, middle-, and low-income countries.
Methods and Findings: Incidence and history of diabetes-related complications, hospital admissions, and length of stay were recorded in 11,140 patients with type 2 diabetes participating in the Action in Diabetes and Vascular Disease (ADVANCE) study (mean age at entry …