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Full-Text Articles in Medicine and Health Sciences

Targeted Osmotic Lysis: A Novel Approach To Targeted Cancer Therapies, Harry J. Gould, Dennis Paul Apr 2022

Targeted Osmotic Lysis: A Novel Approach To Targeted Cancer Therapies, Harry J. Gould, Dennis Paul

School of Medicine Faculty Publications

The conventional treatment of cancer has been based on the delivery of non-selective toxins and/or ionizing energy that affect both the cancer and normal tissues in the hope of destroying the offending disease before killing the patient. Unfortunately, resistance often develops to these treatments and patients experience severe, dose-limiting adverse effects that reduce treatment efficacy and compromise quality of life. Recent advances in our knowledge of the biology of tumor cells and their microenvironment, the recognition of surface proteins that are unique to specific cancers and essential to cell growth and survival and signaling pathways associate with invasion and metastasis …


A Literature Resource For Those Supporting Patients With Autism Spectrum Disorder And Cancer, Kaylee James Jan 2022

A Literature Resource For Those Supporting Patients With Autism Spectrum Disorder And Cancer, Kaylee James

Psychology Doctoral Specialization Projects

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that impacts both social interaction and patterns of behavior. ASD is rooted in genetic, biological, and environmental causes. Cancer begins when cells grow out of control and there is also a genetic and biological cause of cancer. There is an overlap between the genetic and biological causes of ASD and cancer. As a result, evidence supports an increased risk of developing some types of cancer as well as protective factors for some times of cancer for individuals with ASD. Therefore, individuals with ASD may be at a heightened risk to develop cancer, …