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The Effectiveness Of Selective Serotonin Reuptake Inhibitors For Treatment Of Obsessive-Compulsive Disorder In Adolescents And Children: A Systematic Review And Meta-Analysis, Vijaya P. Kotapati, Ali M. Khan, Sara Dar, Gulshan Begum, Ramya Bachu, Mahwish Adnan, Aarij Zubair, Rizwan A. Ahmed

School of Medicine Publications and Presentations

Background: Obsessive-compulsive disorder (OCD) is a common behavioral disorder among adolescents and children. The selective serotonin reuptake inhibitors (SSRIs) are the first pharmacological choice for this condition due to mild adverse effect profile.

Objective: This systematic review was performed to evaluate the efficacy of SSRI for OCD in adolescents and children.

Methods: Search terms were entered into PubMed, PsycINFO, Scopus, CINAHL, and Google Scholar. The included studies were randomized, placebo-controlled trials of SSRIs conducted in populations of children and adolescents younger than 18 years. Change from baseline Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), end-treatment CY-BOCS with respective SD, and response and …

Trastorno Bipolar En Los Niños: Hechos Actuales [Pediatric Bipolar Disorder: Actual Facts], Víctor M. Joffre-Velázquez, Gerardo García-Maldonado, Atenogenes H. Saldívar-González, Roberto A. Cruz

School of Medicine Publications and Presentations

A general review of clinical reports about the pediatric bipolar disorder (PBD) published in the last 10 year was done, but we included some before that. Data was obtained in the bases PubMed, EbscoHost and OvidSP, using as key words: bipolar disorder, pediatric, children, adolescent and early onset. We select the reports clinical issues of special interest for the diagnosis and treatment and epidemiological reports related to PBD and we had particular care in select those with a good methodology. It was documented that the PBD has being diagnosed more often when good clinic and clinimetric tools are used. Imaging …