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Full-Text Articles in Medicine and Health Sciences

Altering Endoplasmic Reticulum Stress In A Model Of Blast-Induced Traumatic Brain Injury Controls Cellular Fate And Ameliorates Neuropsychiatric Symptoms, Aric Flint Logsdon, Ryan Coddington Turner, Brandon Peter Lucke-Wold, Matthew James Robson, Zachary James Naser, Kelly Elizabeth Smith, Rae Reiko Matsumoto Jan 2014

Altering Endoplasmic Reticulum Stress In A Model Of Blast-Induced Traumatic Brain Injury Controls Cellular Fate And Ameliorates Neuropsychiatric Symptoms, Aric Flint Logsdon, Ryan Coddington Turner, Brandon Peter Lucke-Wold, Matthew James Robson, Zachary James Naser, Kelly Elizabeth Smith, Rae Reiko Matsumoto

Faculty Publications & Research of the TUC College of Pharmacy

Neuronal injury following blast-induced traumatic brain injury (bTBI) increases the risk for neuropsychiatric disorders, yet the pathophysiology remains poorly understood. Blood-brain-barrier (BBB) disruption, endoplasmic reticulum (ER) stress, and apoptosis have all been implicated in bTBI. Microvessel compromise is a primary effect of bTBI and is postulated to cause subcellular secondary effects such as ER stress. What remains unclear is how these secondary effects progress to personality disorders in humans exposed to head trauma. To investigate this we exposed male rats to a clinically relevant bTBI model we have recently developed. The study examined initial BBB disruption using Evan’s blue (EB), …


Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel Jan 2014

Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel

The Science Journal of the Lander College of Arts and Sciences

Women who have a history of eating disorders, specifically anorexia nervosa, are more prone to suffer from infertility. There are several hormones which are the driving force in this system and are therefore responsible for this. Fortunately, there are treatments which can help women with a history of eating disorders to reproduce. Using information found on Pubmed and Touro College’s database, this paper will discuss why the body cannot reproduce when it is lacking proper nutrition, as well as the various dynamics in the human reproductive system which are compromised when the body is not properly nourished.