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Full-Text Articles in Medicine and Health Sciences
Depression As A Prognostic Factor For Lumbar Spinal Stenosis Outcomes, Ariel M. Morales
Depression As A Prognostic Factor For Lumbar Spinal Stenosis Outcomes, Ariel M. Morales
Electronic Thesis and Dissertation Repository
Lumbar spinal stenosis (LSS) is a degenerative disease common in older adults and is associated with significantly reduced health-related quality of life and increased disability. Depression has been found to be associated with poorer health-related outcomes in patients with spinal conditions. A systematic review was conducted to examine the literature regarding the prognostic value of depression for LSS outcomes. Findings suggest small to moderate prognostic value of depressive symptoms for postoperative outcomes in patients with LSS, with strong evidence for disability. Next, a secondary analysis of a cohort study was conducted to investigate two objectives. The first objective was to …
Sexual Reward And Depression, Andrea R. Di Sebastiano
Sexual Reward And Depression, Andrea R. Di Sebastiano
Electronic Thesis and Dissertation Repository
Sexual behavior in male rats is a complex rewarding behavior and many neurotransmitters and neuropeptides play an important role in mediation of sexual performance, motivation and reward. The hypothalamic neuropeptide orexin has been shown play a key role in reward associated with food and drugs of abuse, but the role of this neuropeptide in control of sexual performance, motivation and reward is currently unclear. First, it was shown that orexin neurons in the hypothalamus are activated during sexual performance and reward. Next, using cell specific lesions of orexin neurons it was demonstrated that orexin is involved in arousal and anxiety, …