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Does Exogenous Melatonin Improve Quality Of Sleep In Patients Experiencing Sleep Disturbances Secondary To Chronic Diseases?, Blessen B. Thomas
Does Exogenous Melatonin Improve Quality Of Sleep In Patients Experiencing Sleep Disturbances Secondary To Chronic Diseases?, Blessen B. Thomas
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this selective EBM review is to determine whether or not “Does exogenous melatonin improve quality of sleep in patients experiencing sleep disturbances secondary to chronic diseases?”
Study Design: Three Randomized, placebo-controlled studies (RCT) published in 2010, 2013 and 2008. Data Sources: All RCTs searched and located using PubMed database.
Outcomes Measured: Clinical outcome for all three articles using quality of sleep or quality of life questionnaires such as the Leeds Sleep Evaluation. All of which evaluated POEMs, and were self reported by participants.
Results: In a randomized control study (RCT) by Serfaty et al, sleep quality …
Is Melatonin An Effective Treatment For Sleep Problems In Autism?, Andrew J. Winkler
Is Melatonin An Effective Treatment For Sleep Problems In Autism?, Andrew J. Winkler
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not melatonin is an effective treatment for sleep problems in Autism.
STUDY DESIGN: Review of three English language, randomized controlled blinded trials published within peer-reviewed journals from 2006-2010 evaluating the efficacy of Melatonin as an oral sleep supplement in diagnosed autistic children.
DATA SOURCES: A double blind, randomized, placebo-controlled, crossover trial; a randomized controlled crossover trial; and a randomized controlled trial found using Cochrane, PubMed, and DynaMed.
OUTCOMES MEASURED: Total night’s sleep duration, number of awakenings, and sleep latency time were all measured …