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Zucker School of Medicine at Hofstra/Northwell
Autism spectrum disorder;; Cognition;; Emotion;; Executive function;; fMRI;; functional magnetic-resonance;; spectrum disorders;; asperger-syndrome;; behavioral-response;; spatial attention;; bipolar disorder;; fusiform;; gyrus;; cognitive set;; facial affect;; go/no-go;; Neurosciences & Neurology;; Pharmacology & Pharmacy;; Psychiatry
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Full-Text Articles in Medicine and Health Sciences
Neural Systems Mediating Decision-Making And Response Inhibition For Social And Nonsocial Stimuli In Autism, K. M. Shafritz, J. D. Bregman, T. Ikuta, P. R. Szeszko
Neural Systems Mediating Decision-Making And Response Inhibition For Social And Nonsocial Stimuli In Autism, K. M. Shafritz, J. D. Bregman, T. Ikuta, P. R. Szeszko
Journal Articles
Autism is marked by impairments in social reciprocity and communication, along with restricted, repetitive and stereotyped behaviors. Prior studies have separately investigated social processing and executive function in autism, but little is known about the brain mechanisms of cognitive control for both emotional and nonemotional stimuli. We used functional magnetic resonance imaging to identify differences in neurocircuitry between individuals with high functioning autism (HFA) and neurotypical controls during two versions of a go/no-go task: emotional (fear and happy faces) and nonemotional (English letters). During the letter task, HFA participants showed hypoactivation in the ventral prefrontal cortex. During the emotion task, …