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Zucker School of Medicine at Hofstra/Northwell
Arid1a;; Swi/snf;; chromatin remodeling;; targeted therapy;; tumor suppressor gene
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Full-Text Articles in Medicine and Health Sciences
Prognostic Role And Implications Of Mutation Status Of Tumor Suppressor Gene Arid1a In Cancer: A Systematic Review And Meta-Analysis, C. Luchini, N. Veronese, M. Solmi, H. Cho, J. H. Kim, S. Kyo, S. Y. Lee, D. W. Kim, G. M. Yousef, C. U. Correll, +22 Additional Authors
Prognostic Role And Implications Of Mutation Status Of Tumor Suppressor Gene Arid1a In Cancer: A Systematic Review And Meta-Analysis, C. Luchini, N. Veronese, M. Solmi, H. Cho, J. H. Kim, S. Kyo, S. Y. Lee, D. W. Kim, G. M. Yousef, C. U. Correll, +22 Additional Authors
Journal Articles
Loss of the tumor suppressor gene AT-rich interactive domain-containing protein 1A (ARID1A) has been demonstrated in several cancers, but its prognostic role is unknown. We aimed to investigate the risk associated with loss of ARID1A (ARID1A-) for all-cause mortality, cancer-specific mortality and recurrence of disease in subjects with cancer. PubMed and SCOPUS search from database inception until 01/31/2015 without language restriction was conducted, contacting authors for unpublished data. Eligible were prospective studies reporting data on prognostic parameters in subjects with cancer, comparing participants with presence of ARID1A (ARID1A+) vs. ARID1A-, assessed either via immunohistochemistry (loss of expression) or with genetic …