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Zucker School of Medicine at Hofstra/Northwell
Adolescent;; Adult;; Brain Mapping;; Case-Control Studies;; Cerebellum/*physiopathology;; Cerebral Cortex/*physiopathology;; Child;; Disease Progression;; Female;; Follow-Up Studies;; Functional Neuroimaging;; Humans;; Magnetic Resonance Imaging;; Male;; Neural Pathways/physiopathology;; *Prodromal Symptoms;; Psychotic Disorders/*physiopathology;; Risk;; Schizophrenia/*physiopathology;; Thalamus/*physiopathology;; Young Adult
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Full-Text Articles in Medicine and Health Sciences
Association Of Thalamic Dysconnectivity And Conversion To Psychosis In Youth And Young Adults At Elevated Clinical Risk, A. Anticevic, K. Haut, J. D. Murray, G. Repovs, B. Goodyear, K. S. Cadenhead, H. Mirzakhanian, B. A. Cornblatt, D. Olvet, T. D. Cannon, +16 Additional Authors
Association Of Thalamic Dysconnectivity And Conversion To Psychosis In Youth And Young Adults At Elevated Clinical Risk, A. Anticevic, K. Haut, J. D. Murray, G. Repovs, B. Goodyear, K. S. Cadenhead, H. Mirzakhanian, B. A. Cornblatt, D. Olvet, T. D. Cannon, +16 Additional Authors
Journal Articles
IMPORTANCE: Severe neuropsychiatric conditions, such as schizophrenia, affect distributed neural computations. One candidate system profoundly altered in chronic schizophrenia involves the thalamocortical networks. It is widely acknowledged that schizophrenia is a neurodevelopmental disorder that likely affects the brain before onset of clinical symptoms. However, no investigation has tested whether thalamocortical connectivity is altered in individuals at risk for psychosis or whether this pattern is more severe in individuals who later develop full-blown illness. OBJECTIVES: To determine whether baseline thalamocortical connectivity differs between individuals at clinical high risk for psychosis and healthy controls, whether this pattern is more severe in those …