Medicine and Health Sciences Commons^™

Synthesis Of Dihydroisoquinolines And Tetrahydroisoquinolines, John J. Schlager

Chemistry & Biochemistry Theses & Dissertations

Dihydroisoquinolines and tetrahydroisoquinolines are compounds which possess a variety of pharmacological activities. New easier methods of synthetic manipulations of these structures is of constant interest in the pharmaceutical industry.

This paper describes a new three step method of preparing 1-alkyl- and 1-aryl-tetrahydroisoquinolines from a tetrahydroisoquinoline. The synthesis involves the N-chlorination of tetrahydroisoquinoline followed by dehydrohalogenation with potassium superoxide. The reaction products are the dihydroisoquinolines. Overall yields range from 85-96%. The unsubstituted, 1-methyl-, and 1-phenyl-J,4-dihydroisoquinolines have been formed. Organometallation of the unsubstituted dihydroisoquinoline provides the 1-substituted tetrahydroisoquinoline. The 1-benzyl-, 1-n-butyl-, 1-ethyl-, 1-methyl-, and 1-phenyl-1,2,J,4-tetrahydroisoquinolines were prepared. The use of Grignard and …

Algal Dynamics In A Cypress Stand In The Seasonally Flooded Great Dismal Swamp, Joseph A. Atchue Iii

Biological Sciences Theses & Dissertations

The dynamics of epiphytic algae and phytoplankton were studied at a cypress stand in the Great Dismal Swamp, Virginia. Mean epiphytic algal biomass was 19.9 g m^-2 and mean planktonic biomass was 3.4 g m^-2.Nutrient concentrations in the epiphytic algae and the litter were determined. The algae had mean concentrations of 1.67% and 0.18%. They were found to immobilize as much as 0.5 g N m^-2 and 0.06 g P m^-2. This suggests that the algae are important as nutrient conservers. The phytoplankton were composed primarily of Bacillariophyceae. They exhibited a more or less …

Santa Clara Magazine, Volume 24 Number 1, Fall 1981, Santa Clara University

Santa Clara Magazine

3- MEDIA AND MASS PSYCHOLOGY A not too gentle probe of the news media today. By Jerome Kroth.

9 - SAINTS, DIAMONDS AND BEARS A thoughtful comparison of education , today and 40 years ago. By William J. Rewak, S.J.

12 - SANTA CLARA POTPOURRI A chance to test your memory of campus features.

14 - THREE FOR ALL SEASONS Examining the interrelationship of three great Christian humanists. By Christiaan T. Lievestro.

18 - WHERE IS LOVE? Defining love in the new Catholic marriage law. By Theodore Mackin, S.J.

23 - TRACKING THE HIGH TECH BOOM The Silicon Valley is …

Low Pressure Membrane Separation Process To Remove Heavy Metal Complexes, Dibakar Bhattacharyya, Chin-Shun Cheng

KWRRI Research Reports

The overall objective of this investigation is to establish the rejection behavior of heavy metals in the presence of complexing agents, utilizing negatively charged ultrafiltration membranes. An extensive experimental investigation is conducted with Zn²⁺, Cd²⁺, Cu²⁺, and Cu¹⁺ in the presence of cyanide, ethylenediamine tetraacetic acid, and oxalates, under insignificant concentration polarization condition. The rejection dependence of the heavy metals is found to be a function of feed metal concentration, metal types, complexing agent to metal feed molar ratio, pH and ionic strength. The dependence of rejection behavior of heavy metals and complexing …

The Effect Of Hypercholesterolemia On The Membrane Lipids, 3-0-[¹⁴C] Methylglucose Transport, And 2,3-Diphosphoglycerate Levels In Rat Erythrocytes, Edwin J. Lester Jr.

Loma Linda University Electronic Theses, Dissertations & Projects

An increase in dietary cholesterol and cholic acid will produce hypercholesterolemia in rats. For ten months, two groups of rats (six in each group) were fed commercial rat pellets (control group) or rat pellets plus cholesterol (1%) and cholic acid (0.25%) (experimental group). A blood sample from each animal was divided into three aliquots for three separate experiments on the erythrocytes: a membrane cholesterol and phospholipid determination, a 3-0-[¹⁴C] methylglucose (30MG) transport determination, and a 2,3-diphosphoglycerate (2,3 DPG) determination. The 30MG transport and 2,3 DPG aliquots were each incubated in the same five concentrations of 30MG and glucose …

Petroleum-Utilizing Bacteria: The Biological Line Defense Against Oil Pollution, Steven W. Sokolowski

Biological Sciences Theses & Dissertations

A silica gel-petroleum (SGP) medium was developed which is reliable, approximately the same cost as that of the corresponding agar-based petroleum medium, and can be made sufficiently firm to use in streaking or the spread-plate technique. Advantages of the medium include: the incorporation of all of the major ions of seawater in accordance with Dittmar's Law (the salinity of which can easily be varied from 0 to 35 parts per thousand); a wide workable pH range (5.5 to 11.6); negligable pH drift(~ 0.2 pH units after 166 days); the elimination of all but negligable amounts of syneresis, the ability to …

Support Systems Of Mexican-American Women And Their Attitudes Regarding Infant Feeding, Susan Marie Krantz

Loma Linda University Electronic Theses, Dissertations & Projects

This was a descriptive study of 37 recently migrated to the United States, Spanish-speaking, Mexican-American women. Attitudes and support systems associated with their choice to breast or bottle feed their infants were studied. The purpose of this research was to answer the following questions:

1. What are the differences in the attitudes of Mexican- American primiparas who choose to breast feed and those who choose to bottle feed?

2. What are the differences in the practice, recommendations, and proximity of location of significant members of the women's support systems?

Twenty-one breast feeders and 16 bottle feeders were interviewed in Spanish …

Dickey-Lincoln School Lakes Project At Dickey, Maine : Final Environmental Statement, New England Division, United States Army Engineer Division

Dickey-Lincoln School Lakes Project

This document contains those comments and responses on the Revised Draft Environmental Impact Statement. It is a continuation of Volume II published by the Corps in 1978. In addition, it contains reproductions of those letters of comment received on the March 1980 Draft Fish and Wildlife Mitigation Plan, and the responses to these comments.

Loose Smut Of Barley. Sub-Clover Root Rot. Rapeseed Diseases., M. J. Barbetti

Experimental Summaries - Plant Research

Loose smut of barley. Fungicidal control of loose smut in barley – 81MT31, 81NA29. Sub-clover root rot. Fungicidal control of pythium sp – 81AL37, 81BU3. Rapeseed diseases. 1. Rapeseed varieties/Lancelin blackleg strain – 81MO24. 2. Rapeseed varieties/Sclerotinia disease – 81MT32. 3. White leaf spot and grey stem of rapeseed – 81MT33.

Barley Disease, Scald, Spot Type Net Blotch, Powdery Mildew, Leaf Diseases, Double Cropping, Resistance Of Cvt Barley, T N. Khan

Experimental Summaries - Plant Research

I. Barley disease survey and an unidentified disorder on forrest barley. II. Scald: crop loss assessment – 81BA20, 81A17, 81MT23, 81WH30, 81A17, 81BA20, 81MT23, 81WH30, III. Scald: epidemics in simulated populations segregating for scald resistance – 81BA22, 81MT25, 81BA22, 81MT25. IV. Scald: reactions in single plant and hill plots – 81MT24, 81MT21, 81BA21, V. Spot type net blotch: crop loss assessment – 81C17. VI. Net blotch: effect of grazing on infection levels – 81A20. VII. Powdery mildew: crop loss assessment – 81PE5. VIII. Value of whole plot scores in assessing leaf diseases. IX. Disease and yield in simulated double cropping …

Growth Regulator Trials. Part 1, M W. Perry, R N. Weir

Experimental Summaries - Plant Research

This summary covers 1981 trials on chlormequat plant growth regulant (formulated as Cycocel 750A or Halloween), ECO organic seed dressing and a range of organic foliar sprays. Rates and times of application of chlormequat on wheat. 81A22, 81BA3, 81Cl8, 81E25, 81M22, 81MT2, 81N4, 81SG36, 81WH4. Effects of chlormequat on wheat varieties (S4 trials). 81A6, 81BA7, 81C6, 81E6, 81M9, 81M13, 81MT9, 81N10, 81SG26, 81WH19. Trials comparing organic seed treatments, organic foliar sprays and plant growth regulators. 81WH61, 81LG34, 81LG48, 81ME27a, 81ME276, 81TS39, 81ES51, 81ES52, 81ES53, 81ES54, 81NA57, 81N4A, 81MT2A, 81TS38A. H. McCashney, Cadoux Un-numbered, Newdegate Research Station.

Acute Headaches; Presenting Symptoms And Diagnostic Rules To Identify Patients With Tension And Migraine Headache , Paula Diehr

Paula Diehr

Headache is the ninth most common cause of physician visits, but data on acute headaches have not been collected in a standardized manner and have not been analyzed in a multivariate fashion. We report on 726 patients presenting with acute headaches, which were diagnosed as tension (38%), migraine (25%), no diagnosis (30%), and other (6%). The prevalence of 32 signs and symptoms is shown for each group. Four of these findings were significant predictors of tension headache, and 19 were significant predictors of migraine headache (p<.05). Several diagnostic rules are developed which classify nearly 90% of the headaches correctly, using only three to seven of the findings. On a new set of patients the classification was correct over 80% of the time. It is suggested that most acute headaches could be diagnosed over the telephone or by midlevel providers, which would provide substantial cost savings.

The Gamut: A Journal Of Ideas And Information, No. 02, Winter 1981, Cleveland State University

The Gamut Archives

CONTENTS OF ISSUE NO.2, WINTER, 1981

Stuart M. Klein: The Business of City Management, 3

Anthony Addison: The Un-Person Without Whom Opera Would Not Exist, 13

Walter T. Olson: Visiting the Planets, 22

Cyril A. Dostal: Two Poems, 36

Mother and the White Slavers

Starting the Model T

Patrick de Winter: Art, Devotion and Satire -the Book of Hours of Charles the Noble, King of Navarre, 42

Helen A. Weinberg: The Novel in America Today, 60

Abe Frajndlich: Homage to Yukio Mishima -A Portfolio of Photographs, 67

Grace Butcher: Remembering Stella Walsh, 76

Earl R. Anderson: Athletic Mysticism in the …

Comparative In Vitro Studies On Bond Strength And Sealant Polymerization, Gerald E. Sievers

Loma Linda University Electronic Theses, Dissertations & Projects

A comparison of two orthodontic sealants and two adhesives was made. An experimental adhesive was tested (Unitek*) also an experimental sealant (Unitek**) was evaluated for its ability to polymerize into a thin film. An established adhesive and sealant system (Concise***) was compared with the above products.

The factors which were considered important to the study were: the strength of the bond formed; the working efficiency; the ability for these materials to bond to the lingual of teeth; and the value of using contralateral teeth when testing bond strength.

An Instron testing machine was used to record the shear strength of …

Protective Effects Of Certain Lythraceae Alkaloids And Homologs In Croton Oil- And Carrageenan-Induced Inflammation, John Alan Byrne

University of the Pacific Theses and Dissertations

Cryogenine's immunosuppressive activity was first evaluated by Kosersky, et al. (21) who, impressed by the drug's ability to inhibit both the irritant- and immune- mediated phases of adjuvant-induced polyarthritis (11), quantitatively confirmed this activity and clearly differentiated the action of cryogenine from that displayed by 6-mercaptopurine. A definitive study by Watson and Malone (22) confirmed cryogenine's lack of immunosuppressive capacity at effective anti-inflammatory dose levels.

The molecular complexity of the lythraceae alkaloids suggests that several active centers may account for their unique pharmacological profile. To assess these potentially active sites, two standard models of acute inflammation were selected for use …