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Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

Physical Sciences and Mathematics

Laura B. Balzer

Selected Works

2017

Articles 1 - 4 of 4

Full-Text Articles in Medicine and Health Sciences

Sustainable East Africa Research In Community Health (Search): A Community Cluster Randomized Study Of Hiv "Test And Treat" Using Multi-Disease Approach In Rural Uganda And Kenya, Laura Balzer, Diane V. Havlir, Joshua Schwab, Mark J. Van Der Laan, Maya Petersen Nov 2017

Sustainable East Africa Research In Community Health (Search): A Community Cluster Randomized Study Of Hiv "Test And Treat" Using Multi-Disease Approach In Rural Uganda And Kenya, Laura Balzer, Diane V. Havlir, Joshua Schwab, Mark J. Van Der Laan, Maya Petersen

Laura B. Balzer

This document provides the analytic plan for evaluating adult HIV incidence, health, and implementation outcomes for the first phase of the SEARCH Study. Locked: November 27, 2017. Embargoed until July 25, 2018.

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Causal Inference In A Big Data World: The Roadmap, Laura Balzer Sep 2017

Causal Inference In A Big Data World: The Roadmap, Laura Balzer

Laura B. Balzer

No abstract provided.

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Constrained Binary Classification Using Ensemble Learning: An Application To Cost-Efficient Targeted Prep Strategies, Wenjing Zheng, Laura Balzer, Mark J. Van Der Laan, Maya Petersen, Search Collaboration Feb 2017

Constrained Binary Classification Using Ensemble Learning: An Application To Cost-Efficient Targeted Prep Strategies, Wenjing Zheng, Laura Balzer, Mark J. Van Der Laan, Maya Petersen, Search Collaboration

Laura B. Balzer

Binary classification problems are ubiquitous in health and social sciences. In many cases, one wishes to balance two competing optimality considerations for a binary classifier. For instance, in resource-limited settings, an human immunodeficiency virus prevention program based on offering pre-exposure prophylaxis (PrEP) to select high-risk individuals must balance the sensitivity of the binary classifier in detecting future seroconverters (and hence offering them PrEP regimens) with the total number of PrEP regimens that is financially and logistically feasible for the program. In this article, we consider a general class of constrained binary classification problems wherein the objective function and the constraint …

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Evaluation Of Progress Towards The Unaids 90-90-90 Hiv Care Cascade: A Description Of Statistical Methods Used In An Interim Analysis Of The Intervention Communities In The Search Study, Laura Balzer, Joshua Schwab, Mark J. Van Der Laan, Maya L. Petersen Feb 2017

Evaluation Of Progress Towards The Unaids 90-90-90 Hiv Care Cascade: A Description Of Statistical Methods Used In An Interim Analysis Of The Intervention Communities In The Search Study, Laura Balzer, Joshua Schwab, Mark J. Van Der Laan, Maya L. Petersen

Laura B. Balzer

WHO guidelines call for universal antiretroviral treatment, and UNAIDS has set a global target to virally suppress most HIV-positive individuals. Accurate estimates of population-level coverage at each step of the HIV care cascade (testing, treatment, and viral suppression) are needed to assess the effectiveness of "test and treat" strategies implemented to achieve this goal. The data available to inform such estimates, however, are susceptible to informative missingness: the number of HIV-positive individuals in a population is unknown; individuals tested for HIV may not be representative of those whom a testing intervention fails to reach, and HIV-positive individuals with a viral …

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