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Medicine and Health Sciences Commons

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Physical Sciences and Mathematics

Dissertations & Theses (Open Access)

2010

Measurement

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Benchmarking And Implementation Of A New Independent Monte Carlo Dose Calculation Quality Assurance Audit Tool For Clinical Trials, Scott E. Davidson Aug 2010

Benchmarking And Implementation Of A New Independent Monte Carlo Dose Calculation Quality Assurance Audit Tool For Clinical Trials, Scott E. Davidson

Dissertations & Theses (Open Access)

Introduction Commercial treatment planning systems employ a variety of dose calculation algorithms to plan and predict the dose distributions a patient receives during external beam radiation therapy. Traditionally, the Radiological Physics Center has relied on measurements to assure that institutions participating in the National Cancer Institute sponsored clinical trials administer radiation in doses that are clinically comparable to those of other participating institutions. To complement the effort of the RPC, an independent dose calculation tool needs to be developed that will enable a generic method to determine patient dose distributions in three dimensions and to perform retrospective analysis of radiation …