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2019

Articles 1 - 5 of 5

Full-Text Articles in Medicine and Health Sciences

Pathological Comparisons Of The Hippocampal Changes In The Transient And Permanent Middle Cerebral Artery Occlusion Rat Models, Fawad Ali Shah, Tao Li, Lina Tariq Al Kury, Alam Zeb, Shehla Khatoon, Gongping Liu, Xifei Yang, Fang Liu, Huo Yao, Arif Ullah Khan, Phil Ok Koh, Yuhua Jiang, Shupeng Li Nov 2019

Pathological Comparisons Of The Hippocampal Changes In The Transient And Permanent Middle Cerebral Artery Occlusion Rat Models, Fawad Ali Shah, Tao Li, Lina Tariq Al Kury, Alam Zeb, Shehla Khatoon, Gongping Liu, Xifei Yang, Fang Liu, Huo Yao, Arif Ullah Khan, Phil Ok Koh, Yuhua Jiang, Shupeng Li

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© Copyright © 2019 Shah, Li, Kury, Zeb, Khatoon, Liu, Yang, Liu, Yao, Khan, Koh, Jiang and Li. Ischemic strokes are categorized by permanent or transient obstruction of blood flow, which impedes delivery of oxygen and essential nutrients to brain. In the last decade, the therapeutic window for tPA has increased from 3 to 5–6 h, and a new technique, involving the mechanical removal of the clot (endovascular thrombectomy) to allow reperfusion of the injured area, is being used more often. This last therapeutic approach can be done until 24 h after stroke onset. Due to this fact, more acute …

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Follow-Up Decision Support Tool For Public Healthcare: A Design Research Perspective, Shah J. Miah, Najmul Hasan, John Gammack Oct 2019

Follow-Up Decision Support Tool For Public Healthcare: A Design Research Perspective, Shah J. Miah, Najmul Hasan, John Gammack

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© 2019, Korean Society of Medical Informatics. All rights reserved. Objectives: Mobile health (m-Health) technologies may provide an appropriate follow-up support service for patient groups with post-treatment conditions. While previous studies have introduced m-Health methods for patient care, a smart system that may provide follow-up communication and decision support remains limited to the management of a few specific types of diseases. This paper introduces an m-Health solution in the current climate of increased demand for electronic information exchange. Methods: Adopting a novel design science research approach, we developed an innovative solution model for post-treatment follow-up decision support interaction for use …

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The Security Of Big Data In Fog-Enabled Iot Applications Including Blockchain: A Survey, Noshina Tariq, Muhammad Asim, Feras Al-Obeidat, Muhammad Zubair Farooqi, Thar Baker, Mohammad Hammoudeh, Ibrahim Ghafir Apr 2019

The Security Of Big Data In Fog-Enabled Iot Applications Including Blockchain: A Survey, Noshina Tariq, Muhammad Asim, Feras Al-Obeidat, Muhammad Zubair Farooqi, Thar Baker, Mohammad Hammoudeh, Ibrahim Ghafir

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© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The proliferation of inter-connected devices in critical industries, such as healthcare and power grid, is changing the perception of what constitutes critical infrastructure. The rising interconnectedness of new critical industries is driven by the growing demand for seamless access to information as the world becomes more mobile and connected and as the Internet of Things (IoT) grows. Critical industries are essential to the foundation of today’s society, and interruption of service in any of these sectors can reverberate through other sectors and even around the globe. In today’s hyper-connected world, the …

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Methodologies For Designing Healthcare Analytics Solutions: A Literature Analysis, Shah J. Miah, John Gammack, Najmul Hasan Jan 2019

Methodologies For Designing Healthcare Analytics Solutions: A Literature Analysis, Shah J. Miah, John Gammack, Najmul Hasan

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© The Author(s) 2019. Healthcare analytics has been a rapidly emerging research domain in recent years. In general, healthcare solution design studies focus on developing analytic solutions that enhance product, process and practice values for clinical and non-clinical decision support. The objective of this study is to explore the scope of healthcare analytics research and in particular its utilisation of design and development methodologies. Using six prominent electronic databases, qualifying articles between 2010 and mid-2018 were sourced and categorised. A total of 52 articles on healthcare analytics solutions were selected for relevant content on public healthcare. The research team scrutinised …

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Neuroprotective Effects Of Melatonin And Celecoxib Against Ethanol-Induced Neurodegeneration: A Computational And Pharmacological Approach, Lina T. Al Kury, Alam Zeb, Zain Ul Abidin, Nadeem Irshad, Imran Malik, Arooj Mohsin Alvi, Atif Ali Khan Khalil, Sareer Ahmad, Muhammad Faheem, Arif Ullah Khan, Fawad Ali Shah, Shupeng Li Jan 2019

Neuroprotective Effects Of Melatonin And Celecoxib Against Ethanol-Induced Neurodegeneration: A Computational And Pharmacological Approach, Lina T. Al Kury, Alam Zeb, Zain Ul Abidin, Nadeem Irshad, Imran Malik, Arooj Mohsin Alvi, Atif Ali Khan Khalil, Sareer Ahmad, Muhammad Faheem, Arif Ullah Khan, Fawad Ali Shah, Shupeng Li

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© 2019 Al Kury et al. This work is published and licensed by Dove Medical Press Limited. Purpose: Melatonin and celecoxib are antioxidants and anti-inflammatory agents that exert protective effects in different experimental models. In this study, the neuroprotective effects of melatonin and celecoxib were demonstrated against ethanol-induced neuronal injury by in silico, morphological, and biochemical approaches. Methods: For the in silico study, 3-D structures were constructed and docking analysis performed. For in vivo studies, rats were treated with ethanol, melatonin, and celecoxib. Brain samples were collected for biochemical and morphological analysis. Results: Homology modeling was performed to build 3-D …

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