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Full-Text Articles in Medicine and Health Sciences
Distribution, Quantification And Toxicity Of Cinnamaldehyde In Electronic Cigarette Refill Fluids And Aerosols, Rachel Z. Behar, Wentai Luo, Sabrina C. Lin, Yuhuan Wang, Jackelyn Valle, James F. Pankow, Prue Talbot
Distribution, Quantification And Toxicity Of Cinnamaldehyde In Electronic Cigarette Refill Fluids And Aerosols, Rachel Z. Behar, Wentai Luo, Sabrina C. Lin, Yuhuan Wang, Jackelyn Valle, James F. Pankow, Prue Talbot
Chemistry Faculty Publications and Presentations
Objective The aim of this study was to evaluate the distribution, concentration and toxicity of cinnamaldehyde in electronic cigarette (e-cigarette) refill fluids and aerosols.
Methods The distribution and concentration of cinnamaldehyde were determined in 39 e-cigarette refill fluids plus 6 duplicates using gas chromatography and mass spectrometry (GC/MS). A cinnamaldehyde toxicity profile was established for embryonic and adult cells using a live cell imaging assay, immunocytochemistry, the comet assay and a recovery assay.
Results Twenty of the 39 refill fluids contained cinnamaldehyde at concentrations that are cytotoxic to human embryonic and lung cells in the MTT assay. Cinnamon Ceylon aerosol …