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Design And Evaluation Of Peptide Lipid-Associated Nucleic Acids (Planas) For Sirna And Crispr/Cas9 Delivery And Protein Silencing, Ryley Hall
Pharmaceutical Sciences (MS) Theses
Breast cancer affects 1 in 8 women in the United States. The American Cancer Society has estimated that in 2020 about 276,480 new cases of invasive breast cancer will be diagnosed in women. Cancer research has taken a turn in the last several decades to focus on new approaches to combat the disease. This project focuses on two approaches, siRNA and CRISPR/Cas9 that can have potential applications in cancer research.
The first approach is a specific type of RNA interference (RNAi) that has been pursued due to its therapeutic potential in cancer research. In short, siRNA delivery is a method …