Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Are First Generation Immigrants More Inclined To Participate In Clinical Research?, Aisha Farha
Are First Generation Immigrants More Inclined To Participate In Clinical Research?, Aisha Farha
Master's Theses and Doctoral Dissertations
The number of immigrants entering the United States has increased dramatically in the past 30 years, but minorities and ethnic groups are underrepresented in research studies. This study examined first- and second-generation Arab American immigrants in Dearborn, Michigan, using a survey from 65 participants to determine the impact of generation on clinical research participation. Fifty-one (78%) of the respondents were first-generation immigrants, and 14 (22%) were second generation. There was no statistical difference between first- and second-generation immigrants in their willingness to participate in clinical research. Further research with a larger and more diverse population is needed to evaluate willingness …
Regulatory Issues Concerning The Preclinical Testing Of Synthetic Peptides, Vamsi Vardhan Niraghatam
Regulatory Issues Concerning The Preclinical Testing Of Synthetic Peptides, Vamsi Vardhan Niraghatam
Master's Theses and Doctoral Dissertations
Any new drug or biological product undergoes rigorous testing in animals and humans for review by the United States Food and Drug Administration (FDA) before it becomes available for human use. A sponsor files an investigational new drug (IND) application with the FDA with supporting animal data, after which testing is continued with humans. There is sufficient guidance from the FDA on new small molecules and biological products as to which preclinical studies are to be conducted. Synthetic peptides present a unique scenario in which a case-by-case approach is needed for the conduct of preclinical studies. For peptides containing components …
Are Clinical Research Professionals More Inclined To Participate In Clinical Trials?, Rania Mohammad Felemban
Are Clinical Research Professionals More Inclined To Participate In Clinical Trials?, Rania Mohammad Felemban
Master's Theses and Doctoral Dissertations
The objective of this study was to identify the impact of professional knowledge and education on a willingness to participate in clinical trials. It hypothesized that there is no statistical difference in the median rank score between clinical research professionals and other post-graduate educated participants. The research question asked whether the clinical research program graduates were more inclined to participate in clinical trials than other groups with a post-graduate education. A cross-sectional quantitative study of 83 clinical research professionals was conducted. All participants were invited to complete a shortened version of the Center for Information and Study on Clinical Research …