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Full-Text Articles in Medicine and Health Sciences
35ci Solid-State Nmr Characterization Of Polymorphs And Cocrystals Of Xylazine Hci, Louae M. Abdulla
35ci Solid-State Nmr Characterization Of Polymorphs And Cocrystals Of Xylazine Hci, Louae M. Abdulla
Electronic Theses and Dissertations
Xylazine HCl (X), a common veterinary analgesic, has four reported polymorphs that are stable under ambient conditions, Form A (Xa), Form X (Xx), Form Z (Xz), and Form M (Xm), and one monohydrate (Xh). A commercial sample of X was found to contain mixtures of polymorphs and previous synthetic approaches proved unreliable and/or unsuccessful for the production of pure phases in high yields. Herein, we report methods for the reliable preparation and interconversion of polymorphs of X (including mechanochemical synthetic pathways), the discovery of a novel polymorph (Xy), and synthesis of three novel cocrystals with coformers containing amide and carboxylic …
Health Insurance Plan Design And Chronic Disease Management, Daniel E. Feldman
Health Insurance Plan Design And Chronic Disease Management, Daniel E. Feldman
Electronic Theses and Dissertations
Each year, Americans spend more money on health care than any other industrialized nation, despite comparable mortality rates for people with risk factors for heart disease. The reasons for this lack of health care value in the US are numerous and complex – including market distortions like supplier-inflated pricing and regulatory structures that enable consumers to utilize ubiquitous, high-cost medical technologies that yield uncertain benefits. Health insurance, once thought to be an insignificant contributor to rising health spending, has changed considerably in the past few decades in ways that make it more accessible and more generous in coverage. Health insurance …