Medicine and Health Sciences Commons^™

Spatial And Temporal Variations Of Screening For Breast And Colorectal Cancer In The United States, 2008 To 2012, Xue Feng, Xi Tan, Ebtihag Alenzi, Pragya Rai, Jongwha Chang

Faculty & Staff Scholarship

Cancer screening tests are important tools to combat cancer-related morbidity and mortality. There is limited up-to-date research on spatial and temporal variations of colorectal and breast cancer screening in the United States.

County-level data of cancer screening adherence rates were generated from 2008 to 2012 Behavioral Risk Factor Surveillance System. We performed the univariate local indicators for spatial analyses (LISA) for the geographic differences of screening adherence rate and the differential LISA for the change of screening adherence rate from 2008 to 2012.

In the univariate LISA, low-to-low clusters were consistently identified in counties of New Mexico, Wyoming, and Mississippi …

Effect Of Soluble Epoxide Hydrolase On The Modulation Of Coronary Reactive Hyperemia: Role Of Oxylipins And Pparγ, Ahmad Hanif, Matthew L. Edin, Darryl C. Zeldin, Christophe Morisseau, Mohammed A. Nayeem

Faculty & Staff Scholarship

Coronary reactive hyperemia (CRH) is a physiological response to ischemic insult that prevents the potential harm associated with an interruption of blood supply. The relationship between the pharmacologic inhibition of soluble epoxide hydrolase (sEH) and CRH response to a brief ischemia is not known. sEH is involved in the main catabolic pathway of epoxyeicosatrienoic acids (EETs), which are converted into dihydroxyeicosatrienoic acids (DHETs). EETs protect against ischemia/reperfusion injury and have numerous beneficial physiological effects. We hypothesized that inhibition of sEH by t-AUCB enhances CRH in isolated mouse hearts through changing the oxylipin profiles, including an increase in EETs/DHETs ratio. Compared …

Depression Treatment Decreases Healthcare Expenditures Among Working Age Patients With Comorbid Conditions And Type 2 Diabetes Mellitus Along With Newly-Diagnosed Depression, Rituparna Bhattacharya, Chan Shen, Amy B. Wachholtz, Nilanjana Dwibedi, Usha Sambamoorthi

Faculty & Staff Scholarship

Background: There are many studies in the literature on the association between depression treatment and health expenditures. However, there is a knowledge gap in examining this relationship taking into account coexisting chronic conditions among patients with diabetes. We aim to analyze the association between depression treatment and healthcare expenditures among adults with Type 2 Diabetes Mellitus (T2DM) and newly-diagnosed depression, with consideration of coexisting chronic physical conditions.

Methods: We used multi-state Medicaid data (2000–2008) and adopted a retrospective longitudinal cohort design. Medical conditions were identified using diagnosis codes (ICD-9-CM and CPT systems). Healthcare expenditures were aggregated for each month for …