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Pharmacy and Pharmaceutical Sciences

Nova Southeastern University

Tissue engineering

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Full-Text Articles in Medicine and Health Sciences

Bioinspired Polymers: Transformative Applications In Biomedicine And Regenerative Medicine., Hossein Omidian, Renae L. Wilson, Niloofar Babanejad Aug 2023

Bioinspired Polymers: Transformative Applications In Biomedicine And Regenerative Medicine., Hossein Omidian, Renae L. Wilson, Niloofar Babanejad

HPD Articles

Bioinspired polymers have emerged as a promising field in biomaterials research, offering innovative solutions for various applications in biomedical engineering. This manuscript provides an overview of the advancements and potential of bioinspired polymers in tissue engineering, regenerative medicine, and biomedicine. The manuscript discusses their role in enhancing mechanical properties, mimicking the extracellular matrix, incorporating hydrophobic particles for self-healing abilities, and improving stability. Additionally, it explores their applications in antibacterial properties, optical and sensing applications, cancer therapy, and wound healing. The manuscript emphasizes the significance of bioinspired polymers in expanding biomedical applications, addressing healthcare challenges, and improving outcomes. By highlighting these …


Advancements And Applications Of Injectable Hydrogel Composites In Biomedical Research And Therapy., Hossein Omidian, Sumana Dey Chowdhury Jun 2023

Advancements And Applications Of Injectable Hydrogel Composites In Biomedical Research And Therapy., Hossein Omidian, Sumana Dey Chowdhury

HPD Articles

Injectable hydrogels have gained popularity for their controlled release, targeted delivery, and enhanced mechanical properties. They hold promise in cardiac regeneration, joint diseases, postoperative analgesia, and ocular disorder treatment. Hydrogels enriched with nano-hydroxyapatite show potential in bone regeneration, addressing challenges of bone defects, osteoporosis, and tumor-associated regeneration. In wound management and cancer therapy, they enable controlled release, accelerated wound closure, and targeted drug delivery. Injectable hydrogels also find applications in ischemic brain injury, tissue regeneration, cardiovascular diseases, and personalized cancer immunotherapy. This manuscript highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research. Moreover, it includes a perspective …


Cryogels: Advancing Biomaterials For Transformative Biomedical Applications., Hossein Omidian, Sumana Dey Chowdhury, Niloofar Babanejad Jun 2023

Cryogels: Advancing Biomaterials For Transformative Biomedical Applications., Hossein Omidian, Sumana Dey Chowdhury, Niloofar Babanejad

HPD Articles

Cryogels, composed of synthetic and natural materials, have emerged as versatile biomaterials with applications in tissue engineering, controlled drug delivery, regenerative medicine, and therapeutics. However, optimizing cryogel properties, such as mechanical strength and release profiles, remains challenging. To advance the field, researchers are exploring advanced manufacturing techniques, biomimetic design, and addressing long-term stability. Combination therapies and drug delivery systems using cryogels show promise. In vivo evaluation and clinical trials are crucial for safety and efficacy. Overcoming practical challenges, including scalability, structural integrity, mass transfer constraints, biocompatibility, seamless integration, and cost-effectiveness, is essential. By addressing these challenges, cryogels can transform biomedical …


Exploring The Potential Of Nanotechnology In Pediatric Healthcare: Advances, Challenges, And Future Directions., Hossein Omidian, Kwadwo Mfoafo May 2023

Exploring The Potential Of Nanotechnology In Pediatric Healthcare: Advances, Challenges, And Future Directions., Hossein Omidian, Kwadwo Mfoafo

HPD Articles

The utilization of nanotechnology has brought about notable advancements in the field of pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and tissue engineering. Nanotechnology involves the manipulation of materials at the nanoscale, resulting in improved drug effectiveness and decreased toxicity. Numerous nanosystems, including nanoparticles, nanocapsules, and nanotubes, have been explored for their therapeutic potential in addressing pediatric diseases such as HIV, leukemia, and neuroblastoma. Nanotechnology has also shown promise in enhancing disease diagnosis accuracy, drug availability, and overcoming the blood-brain barrier obstacle in treating medulloblastoma. It is important to acknowledge that while nanotechnology offers significant opportunities, there …