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Pharmacy and Pharmaceutical Sciences
Manipal Academy of Higher Education
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Full-Text Articles in Medicine and Health Sciences
Formulations And Evaluation Of Mucoadhesive Buccal Tablets Of Anti-Histamine Drug Using Natural Polymers, Shardor Ambarish Ghalappa Shardor Mr, Siddramappa Basavaraj Shirsand Dr, Shailashri Siddramappa Shirsand Mrs, Chandrakant C. Patil Dr
Formulations And Evaluation Of Mucoadhesive Buccal Tablets Of Anti-Histamine Drug Using Natural Polymers, Shardor Ambarish Ghalappa Shardor Mr, Siddramappa Basavaraj Shirsand Dr, Shailashri Siddramappa Shirsand Mrs, Chandrakant C. Patil Dr
Manipal Journal of Nursing and Health Sciences
Introduction: The present investigation highlights the formulation of buccoadhesive tablets of Ketotifen fumarate, a second-generation H1-antihistamine and mast cell stabilizer. The properties of Ketotifen may contribute to its antiallergic activity. Method: The mucoadhesive buccal tablets of Ketotifen fumarate were prepared by direct compression method using natural polymers like sodium alginate, xanthan gum, karaya gum, and gaur gum along with carbopol 934P in different ratios. Ethyl cellulose is used as a backing layer to promote the unidirectional flow of drugs in the buccal region. Results: After examining the flow properties of the powder blends the results were found to be within …