Medicine and Health Sciences Commons^™

Evaluating The Bioavailability Of Carbamazepine Using A Novel Snedds Formulation, Jinwon Byun, Derrick L. Chapman, Rebecca A. Kyper, Gina M. Mattes, Zachary A. Wallace, Elisha R. Injeti

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Central to the mechanism of how drugs work are the concepts of solubility and bioavailability. Drugs enter the body via absorption into the bloodstream, arrive at the target location, and bind to receptors to cause an effect. Drugs need to be soluble enough to pass through the cell membrane to enter and exit the bloodstream. Higher solubility generally correlates to higher bioavailability. Additionally, the smaller the particle size, the easier the drug will pass through the membrane into the blood plasma. Researchers have designed a system to categorize solubility class: Class I being high permeability and high solubility, Class II …

Effectiveness Of Clinical Scenarios In Improving Student Interprofessional Skills And Attitudes, Ashley Peterson, Mike Pelyhes, Laura Cummings, Phillip L. Thornton, Zachary N. Jenkins

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Background: “Interprofessional education (IPE) is defined as the process by which individuals from two or more health professions learn with, from, and about each other across the spectrum of their education to improve collaboration, practice, and the quality of health care.” [1] Interprofessional Education has recently gained interest as an important aspect of training in healthcare professions, attracting the attention and support of several key pharmacy organizations. Various models of IPE have been implemented to facilitate collaboration among medical, nursing, pharmacy, and social work students and professionals. One model found to be particularly effective among pharmacy students is a mock …

Access To Healthy Foods Across America, Aaron D. Le Poire, Ginger D. Cameron, Heather Evankow, Andrea Bashore, Jacob Farran, Jesse Hickey

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Research indicates that individuals who have access to healthy food tend to eat healthier. Food environments that do not have access to healthy food have been shown to be a leading cause of obesity in the United States. Major health consequences of obesity include cardiovascular disease, type 2 diabetes, hypertension, stroke, high cholesterol, gallbladder disease, osteoarthritis, and some cancers. The availability of healthy foods can be determined by median household income, with income levels being shown to affect access to healthy foods in local areas. However, no study has shown if this phenomenon is prevalent across the United States. Our …

The Pivotal Role Of The Pharmacist In A Primary Care Office, Julie Cummings, Olumami O. Amaye, Mckenzie Shenk, Cara Toms, Nathanael Smith, Thaddeus T. Franz, Tracy R. Frame

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Abstract

The profession of pharmacy has evolved from a dispensing role to an interdisciplinary clinical role in patient care. One area of patient care expertise is Medication Therapy Management (MTM), which includes services such as pharmacotherapy, medication therapy reviews, disease management, immunizations and other clinical services. In various studies, pharmacists conducting MTM have shown improved patient outcomes in community pharmacy and hospital settings. Amidst the valuable services all healthcare professionals are providing, increasing medical costs and consequences have become overwhelming, leading to negative patient outcomes. A lack of primary care physicians (PCPs) may contribute to these distressing facts. Gaps in …

Pharmacist Empathy In Smoking Cessation Counseling, Caleb Lyman, Megan Mcnicol, Maria Miller, Yevgeniy Solokha, Kelly J. Wright, Aleda M.H. Chen

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Cigarette smoking and nicotine addiction are prevalent in today’s society. Approximately 19% of American adults (43.8 million people) smoke cigarettes. Smoking is associated with health risks such as Chronic Obstructive Pulmonary Disease (COPD), infertility, low birth weight, respiratory symptoms, heart disease, and lung cancer and is responsible for roughly $96 billion in health care costs. Provider empathy has been proven effective in other treatments like cold and cancer; however, its effectiveness in smoking cessation has not yet been studied. Empathy is defined in two realms: cognitive and affective. In the cognitive domain, individuals have the ability to understand and view …

Efficacy Of Marketing Strategy For Reach Vitamins, Jessica Davis, Jordan Long, Megan Buck, Paul Bicknell, Melody L. Hartzler

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

According to the 2009 Global Report, Vitamin A supplementation in children reduces the death rate by 23% in populations at risk of deficiency. REACH Vitamins is a for-profit business that provides a one-year supply of vitamin A to children in underprivileged countries for each bottle of vitamins A, B, C, D, or the multivitamin purchased. The primary objective of this exploratory, qualitative study is to determine if there is a more appropriate marketing strategy for REACH Vitamins compared to the current marketing strategy used. The secondary objective is to determine if REACH Vitamins’ charity motivates consumers to purchase their products. …

The Impact Of Free Health Screenings At Community Pharmacies On Diabetes, Anna M. Smith, Nicholas C. Daniels, Jessica E. Amtower, Jeniffer George, Jacques N. Allou, Jeb Ballentine, Emily M. Laswell

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Title: The Impact of Free Health Screenings at Community Pharmacies on Diabetes

Authors: Jacques Allou, Jessica Amtower, Nicholas Daniels, Jeniffer George, Anna Smith, Jeb Ballentine, Pharm.D., and Emily Laswell, Pharm.D.

Background: Health screenings can be beneficial when looking to detect diseases early on, thus making treatment easier. Free health screenings are typically performed in the community pharmacy setting. This makes it convenient because it is easily accessible and there is no appointment required. Diabetes is currently one of the most significant health issues faced today, with an estimated 7 million Americans going undiagnosed. Health screenings in community pharmacies are valuable …

Natural Products As Therapeutic Agents In Cancer Treatment, Eric Huseman, Lauren P. Williams, Brittany Santee, Trevor Stump, Chelsae Ward, Rachel Kunze, Denise S. Simpson, Samson Amos

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Cancer accounts for 25% of deaths in the United States, and brain tumors greatly contribute to this percentage. However, relative to other types of cancers, brain tumors prove difficult to treat because they are heterogeneous, highly proliferative, highly invasive, and resistant to the traditional cancer treatments of chemotherapy and radiotherapy. Past studies have shown that flavonoids and curcuminoids, two classes of compounds derived from natural sources, are effective in inhibiting the development and metastasis of breast and lung cancer cells. Research has also indicated that these compounds have potential for treating brain tumors.

The purpose of this research is to …

American College Of Clinical Pharmacy White Paper: Cultural Competency In Health Care And Its Implications For Pharmacy Part 3a: Emphasis On Pharmacy Education, Curriculums, And Future Directions, Mary Beth O'Connell, Magaly Rodriguez De Bittner, Therese Poirier, Lamis R. Karaoui, Margarita Echeverri, Aleda M.H. Chen, Shin-Yu Lee, Deepti Vyas, Christine K. O’Neil, Anita N. Jackson

Pharmacy Practice Faculty Publications

Culture influences patients' beliefs and behaviors toward health and illness. As the U.S. population becomes more diverse, a critical need exists for pharmacy education to incorporate patient-centered culturally sensitive health care knowledge and skills into the curriculum. Nursing was the first profession to incorporate this type of learning and training into its curriculums, followed by medicine. Pharmacy has also made great progress to revise curriculums, but inconsistency exists in depth, breadth, and methods across pharmacy colleges. This article addresses important aspects of pharmacy education such as curriculum development, incorporation of educational innovations and techniques into the teaching of patient-centered culturally …

The Impact Of Free Health Screenings At Community Pharmacies On Diabetes, Anna M. Staudt, Nicholas C. Daniels, Jessica E. Amtower, Jeniffer George, Jacques N. Allou, Jeb Ballentine, Emily M. Laswell

Pharmacy Practice Faculty Presentations

Background: Health screenings can be beneficial when looking to detect diseases early on, thus making treatment easier. Free health screenings are typically performed in the community pharmacy setting. This makes it convenient because it is easily accessible and there is no appointment required. Diabetes is currently one of the most significant health issues faced today, with an estimated 7 million Americans going undiagnosed. Health screenings in community pharmacies are valuable to detect high blood glucose levels for patients to be referred for diagnosis and treatment. Previous studies related to health screenings have focused on hypertension and cholesterol, and few have …

Heart Smart: Healthy Living And Prevention Of Chronic Disease, Ginger D. Cameron

Pharmacy Practice Faculty Presentations

No abstract provided.

A Light In The Pharmacy, Marc A. Sweeney

Pharmacy Faculty Publications

No abstract provided.

The Epidemic In Your Medicine Chest, Jeffrey D. Lewis

Pharmacy Practice Faculty Publications

No abstract provided.

Content Uniformity Of Over-The-Counter Melatonin, Calvin Anderson, Lauren Callahan, Jacob Coleman, Yeseul Kim, Elizabeth C. Ledbetter, Rebecca Widder, Melissa J. Beck

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Dietary supplements are loosely regulated in comparison to over-the-counter and prescription drugs. Numerous tests for safety and efficacy are required before drugs can be marketed. However, the Food and Drug Administration does not require thorough examination of supplements before they are sold. Dietary supplements generally adhere to the phrase, “safe, until proven unsafe,” with safety determined solely through post-market adverse event reports. Substandard regulation of supplement manufacturing leads to warranted doubt about the safety and efficacy of dietary supplements. Within the dietary supplement market there are regulatory bodies, such as the United States Pharmacopeia (USP), that provide optional verification services …

2013 White Coat Ceremony Invitation, School Of Pharmacy, Cedarville University

2013 White Coat Ceremony Documents

No abstract provided.

Pledge Of Professionalism, School Of Pharmacy, Cedarville University

2013 White Coat Ceremony Documents

No abstract provided.

2013 White Coat Ceremony Program, School Of Pharmacy, Cedarville University

2013 White Coat Ceremony Documents

No abstract provided.

Class Of 2017, School Of Pharmacy, Cedarville University

2013 White Coat Ceremony Documents

No abstract provided.

Bile Acid Signal-Induced Phosphorylation Of Small Heterodimer Partner By Protein Kinase Cζ Is Critical For Epigenomic Regulation Of Liver Metabolic Genes, Sunmi Seok, Deepthi Kanamaluru, Zhen Xiao, Daniel Ryerson, Sung-E Choi, Kelly Suino-Powell, H. Eric Xu, Timothy D. Veenstra, Jongsook Kim Kemper

Pharmaceutical Sciences Faculty Publications

Bile acids (BAs) are recently recognized key signaling molecules that control integrative metabolism and energy expenditure. BAs activate multiple signaling pathways, including those of nuclear receptors, primarily farnesoid X receptor (FXR), membrane BA receptors, and FXR-induced FGF19 to regulate the fed-state metabolism. Small heterodimer partner (SHP) has been implicated as a key mediator of these BA signaling pathways by recruitment of chromatin modifying proteins, but the key question of how SHP transduces BA signaling into repressive histone modifications at liver metabolic genes remains unknown. Here we show that protein kinase Cζ (PKCζ) is activated by BA or FGF19 and phosphorylates …

Free Clinic Service: An Opportunity For Pharmacists Too, Kelly J. Wright

Pharmacy Practice Faculty Publications

No abstract provided.

Dsg3 As A Biomarker For The Ultrasensitive Detection Of Cccult Lymph Node Metastasis In Oral Cancer Using Nanostructured Immunoarrays, Vyomesh Patel, Daniel Martin, Ruchika Malhotra, Christina A. Marsh, Colleen L. Doçi, Timothy D. Veenstra, Cherie-Ann O. Nathan, Uttam K. Sinha, Bhuvanesh Singh, Alfredo A. Molinolo, James F. Rusling, J. Silvio Gutkind

Pharmaceutical Sciences Faculty Publications

OBJECTIVES: The diagnosis of cervical lymph node metastasis in head and neck squamous cell carcinoma (HNSCC) patients constitutes an essential requirement for clinical staging and treatment selection. However, clinical assessment by physical examination and different imaging modalities, as well as by histological examination of routine lymph node cryosections can miss micrometastases, while false positives may lead to unnecessary elective lymph node neck resections. Here, we explored the feasibility of developing a sensitive assay system for desmoglein 3 (DSG3) as a predictive biomarker for lymph node metastasis in HNSCC.

MATERIALS AND METHODS: DSG3 expression was determined in multiple general cancer- and …

Development Of A Novel Aspirin Suppository Formulation And Evaluation Of The Acetylation Of Cox-1 Via A Ht-29/Caco-2 Cell Absorption Assay Used To Detect The Absorption Of Aspirin Formulated With Various Bases And Excipients, Tiffany J. Zehel, Danielle L. Eaton, Sarah A. Myers, Mallory J. Martin, Joseph D. Newman, Rocco J. Rotello, Miriam A. Ansong

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

As the baby-boomer population ages, hospitalization rates will rise, increasing the number of patients who are NPO. Research indicates that aspirin use also increases with advanced age. With the increased prevalence of this demographic, there continues to be a growing need for alternative dosage forms for aspirin administration. A common and limited-risk alternative is rectally administered aspirin. However, there appears to be only one commercially available aspirin suppository and it has yielded erratic results as shown in previous research.

Aspirin is considered a pro-drug; once it is inside the body, the acidic environment cleaves the aspirin molecule down to salicylic …

Health Literacy Influences Heart Failure Knowledge Attainment But Not Self-Efficacy For Self-Care Or Adherence To Self-Care Over Time, Aleda M.H. Chen, Karen S. Yehle, Nancy M. Albert, Kenneth F. Ferraro, Holly L. Mason, Matthew M. Murawski, Kimberly S. Plake

Pharmacy Practice Faculty Publications

Background. Inadequate health literacy may be a barrier to gaining knowledge about heart failure (HF) self-care expectations, strengthening self-efficacy for self-care behaviors, and adhering to self-care behaviors over time. Objective. To examine if health literacy is associated with HF knowledge, self-efficacy, and self-care adherence longitudinally. Methods. Prior to education, newly referred patients at three HF clinics (, age: years) completed assessments of health literacy, HF knowledge, self-efficacy, and adherence to self-care at baseline, 2, and 4 months. Repeated measures analysis of variance with Bonferroni-adjusted alpha levels was used to test longitudinal outcomes. Results. Health literacy was associated with HF knowledge …