Medicine and Health Sciences Commons^™

A Study Of Several Factors Incident To The Absorption Of Choline From The Small Intestine Of The Albino Rat, Ralph E. Purdy

University of the Pacific Theses and Dissertations

The substance choline, one of the quaternary nitrogen bases, has been the subject of a number of reviews and investigations. It has been described as a cholinergic agent, an inotropic agent, a vitamin, and perhaps in other ways. In spite of the interest shown in its action and uses, there is as yet very little information available as to the mechanism by which it is absorbed by the intestinal mucosa.

The studies referred to thus far leave the field open for additional investigation. No mention was found in the literature of studies on selective areas of absorption of choline in …

Studies On The Metabolism And Excretion Of Chlorine Chloride, John Thomas Mccloskey

University of the Pacific Theses and Dissertations

The organic base choline is of considerable interest to the physiologist because of its role in normal metabolic function, and to the pharmacologist because of its possible application in the treatment of several human diseases.

The overall function of choline in the biologic system must be seen as an equilibrium between its lipotropic activity as a whole molecule and its function as a source of methyl groups in biochemical reactions.

IV. Investigation Undertaken in This Study

Due to the long-standing and as yet unresolved question dealing with the relative merits of the path by which choline leaves the intestine, these …