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Pharmacy and Pharmaceutical Sciences

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University of the Pacific Theses and Dissertations

1979

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Biofeedback Treatment Of A Drug Induced Tremor, Ralph Nitta Jan 1979

Biofeedback Treatment Of A Drug Induced Tremor, Ralph Nitta

University of the Pacific Theses and Dissertations

Two subjects exhibiting drug-induced hand tremor received EMG feedback from electrode sites above the forearm extensor muscles . EMG feedback resulted in reductions in muscle potentials for both subjects. However, self-report measures of tremor severity showed only general improvement in Subject l and little or no improvement in Subject 2. Behavioral measures of hand steadiness taken immediately after each treatment session showed slight changes across treatment conditions for both subjects. As indicated by a rapid increase in EMG measures during reversal, treatment effects appear transitory.


Investigation Of Lanolin Alcohol As A Film-Forming Delivery System: In Vitro Kinetics Of Triamcinolone Acetonide Release And Skin Penetration., Balasubramanian Venkataraman Iyer Jan 1979

Investigation Of Lanolin Alcohol As A Film-Forming Delivery System: In Vitro Kinetics Of Triamcinolone Acetonide Release And Skin Penetration., Balasubramanian Venkataraman Iyer

University of the Pacific Theses and Dissertations

The nonpolymeric high molecular weight substances such as lanolin alcohol, stearyl alcohol, and cetyl alcohol have been investigated for their film-forming potential. Furthermore, the application of this potential in the design of topical drug-delivery systems has also been explored. The utilization of such film-forming systems may offer certain unique advantages not associated with the polymeric systems.

Stearyl alcohol and cetyl alcohol do not form films of acceptable integrity. Lanolin alcohol forms thin films capable of being isolated. Inclusion of appropriate amounts of ethyl cellulose and propylene glycol or hexadecyl alcohol in lanolin alcohol was found to improve the integrity, hardness …