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Does Early Physical Therapy Intervention Reduce Opioid Burden And Improve Functionality In The Management Of Chronic Lower Back Pain?, Shedrick Martin, Kimberly Tallian, Victoria T Nguyen, Jason Van Dyke, Harminder Sikand

Articles, Abstracts, and Reports

Introduction: Chronic lower back pain is a leading cause of disability in US adults. Opioid use continues to be controversial despite the Centers for Disease Control and Prevention guidance on chronic pain management to use nonpharmacologic and nonopioid pharmacologic interventions. The objectives of the study were to assess the impact of early physical therapy (PT) intervention on improving functionality and reducing opioid burden in patients with chronic lower back pain.

Methods: A single-center, retrospective chart review of patients receiving ≥6 PT visits and treated with either opioids first (OF) or PT first (PTF) therapy for chronic lower back pain were …

Medication Use, Renin-Angiotensin System Inhibitors, And Acute Care Utilization After Hospitalization In Patients With Chronic Kidney Disease., Joshua J Neumiller, Kenn Daratha, Radica Alicic, Robert A Short, Haleigh Miller, Liza Gregg, Brian J Gates, Cynthia F Corbett, Sterling M Mcpherson, Katherine Tuttle

Articles, Abstracts, and Reports

OBJECTIVES: The aims of this secondary analysis were to: (a) characterize medication use following hospital discharge for patients with chronic kidney disease (CKD), and (b) investigate relationships of medication use with the primary composite outcome of acute care utilization 90 days after hospitalization.

METHODS: The CKD-Medication Intervention Trial (CKD-MIT) enrolled acutely ill hospitalized patients with CKD stages 3-5 not dialyzed (CKD 3-5 ND). In this post hoc analysis, data for medication use were characterized, and the relationship of medication use with the primary outcome was evaluated using Cox proportional hazards models.

RESULTS: Participants were taking a mean of 12.6 (standard …