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Zucker School of Medicine at Hofstra/Northwell
Alpha enolase;; antigen;; aquaporin 4;; beta arrestin;; carboxypeptidase H;; chaperonin 60;; chromogranin A;; collagen type 2;; double stranded DNA;; glutamate decarboxylase;; glutamate decarboxylase 65;; insulin;; La antigen;; myelin basic protein;; protein S100B;; proteolipid protein;; antigen based immunotherapy;; article;; autoimmune disease;; celiac disease;; clinical trial (topic);; dendritic cell;; drug safety;; drug targeting;; human;; immunotherapy;; insulin dependent diabetes mellitus;; multiple sclerosis;; nonhuman;; rheumatoid arthritis;; systemic lupus erythematosus
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Full-Text Articles in Medicine and Health Sciences
Antigen-Based Immunotherapy For Autoimmune Disease: Current Status, D. L. Hirsch, P. Ponda
Antigen-Based Immunotherapy For Autoimmune Disease: Current Status, D. L. Hirsch, P. Ponda
Journal Articles
Autoimmune diseases are common chronic disorders that not only have a major impact on the quality of life but are also potentially life-threatening. Treatment modalities that are currently favored have conferred signifcant clinical benefts, but they may have considerable side effects. An optimal treatment strategy for autoimmune disease would specifcally target disease-associated antigens and limit systemic side effects. Similar to allergen-specifc immunotherapy for allergic rhinitis, antigen-specifc immunotherapy for autoimmune disease aims to induce immune deviation and promote tolerance to specifc antigens. In this review, we present the current status of studies and clinical trials in both human and animal hosts …